Brain microstructural abnormalities in patients with Wilson ’s disease: A systematic review of diffusion tenor imaging studies

ConclusionsDTI allows early detection of brain abnormalities associated with WD, prior to the occurrence of morphological brain changes by MRI. Correlations with treatment outcomes and clinical severity may provide objective and quantitative assessment of early and ongoing treatment response. Future studies are required to elucidate the role of DTI in WD clinical practice and find the most consistent DTI markers that may improve clinical outcome.
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research