Confirmation of lung adenocarcinoma as the primary cancer with detection of EML4-ALK rearrangement using next-generation sequencing: a case study

This study suggested that NGS be recommended to detect ALK rearrangement in the patients with carcinoma of unknown primary site, and that resistance to targeted therapy with ALK inhibitors should be considered for personalized precision medicine.PMID:36099717 | DOI:10.1016/j.prp.2022.154105

Source: Pathology, Research and Practice - September 13, 2022 Category: Pathology Authors: Yijun Mo Lina Lin Jianhua Zhang Yan Zhong Tao Zhang Chenghua Zhong Jun Yan Jun Kuang Quanwei Guo Jianfeng Tan Dongfang Li Mengxi Wu Source Type: research