Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF- α-induced inflammatory activation of synovial fibroblasts
This study identified a novel role of Sulf-2 in TNF-α signaling and the activation of RA synoviocytes, providing the rationale for evaluating the therapeutic targeting of Sulf-2 in preclinical models of RA.PMID:36068294 | DOI:10.1038/s41423-022-00913-x
Source: Cellular and Molecular Immunology - Category: Molecular Biology Authors: Ruby J Siegel Anil K Singh Paul M Panipinto Farheen S Shaikh Judy Vinh Sang U Han H Mark Kenney Edward M Schwarz Cynthia S Crowson Sadik A Khuder Basil S Khuder David A Fox Salahuddin Ahmed Source Type: research
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