What Are the Drivers of Readmission for Serious Venous Thromboembolic Events after Primary Total Knee Arthroplasty? An Analysis of 862,915 Patients

This study examines the patient and hospital characteristics associated with readmission for serious VTE after TKA. The National Readmission Database (NRD) from the Agency of Healthcare Research and Quality (AHRQ) was queried for patients who underwent primary TKA from January 2016-December 2018. The study population consisted of patients who were readmitted within 90 days following primary TKA with a primary diagnosis of VTE. Multivariable regression models were constructed to evaluate patient characteristics (age, sex, insurance, elective nature of procedure, hospital characteristics, discharge status, income, and comorbidities) associated with higher risk of developing readmission-requiring VTE. Readmission rates for VTE exhibited a higher incidence in patients older than 61 (compared with 40 and under), males (OR:1.08, 95%CI [1.03–1.14]), patients with nonelective procedures (OR:20.21, 95% CI [19.16–21.32]), patients at large hospitals(OR:1.17, 95% CI [1.09–1.25]), patients at private hospitals (OR:1.19, 95% CI [1.09–1.29]), and patients with non-home discharge statuses. Comorbidities of paralysis (OR:1.52, 95% CI [1.19–1.94]), neurological disorders (OR:1.12, 95% CI [1.02–1.23]), metastatic cancer (OR:1.48, 95% CI [1.01–2.17]), obesity (OR:1.11, 95% CI [1.06–1.17]), fluid and electrolyte imbalance (OR:1.28, 95% CI [1.18–1.38]), blood loss anemia (OR:1.29, 95% CI [1.02–1.64]), and iron deficiency anemia (OR:1.24, 95 % CI [1.15–1.33]) increased risk o...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research