Dual inhibition of autophagy and PI3K/mTOR pathway as a potential therapeutic strategy against laryngeal squamous cell carcinoma

CONCLUSIONS: NVP-BEZ235 exerted potent antitumor effects on LSCC, especially when combined with the autophagy inhibitor both in vitro and vivo, providing convincing experimental data for new molecular targeted therapy for LSCC.PMID:35706786 | PMC:PMC9189222 | DOI:10.21037/tcr-21-2325

Source: Cell Research - June 16, 2022 Category: Cytology Authors: Hui-Ying Huang Ke-Nan Li Hui-Ching Lau Chi-Yao Hsueh Ning Cong Ming Zhang Source Type: research