Indications of younger age at menarche in Greek adolescents but with no relation to body mass index
CONCLUSION: The timing of pubertal stages in the Greek female sample studied followed the recent international downward trends. Younger age at menarche was not related to BMI.PMID:38647964 | DOI:10.1007/s42000-024-00557-8 (Source: Hormones)
Source: Hormones - April 22, 2024 Category: Endocrinology Authors: Anastasia Papageorgiou Evangelia Charmandari Vasiliki Efthymiou Dimitrios Vlachakis Flora Bacopoulou Source Type: research

The effect of GnRH-a on the angiogenesis of endometriosis
CONCLUSIONS: GnRH-a administration does affect some pathways of angiogenesis in endometriotic lesions, but not all of them. Therefore, supplementary treatments that affect the SP1 pathway of angiogenesis should be developed to enhance the antiangiogenetic effect of GnRH-a in patients with endometriosis.TRIAL REGISTRATION: Clinicaltrial.gov ID: NCT06106932.PMID:38639888 | DOI:10.1007/s42000-024-00559-6 (Source: Hormones)
Source: Hormones - April 19, 2024 Category: Endocrinology Authors: Theodoros Filindris Efthymia Papakonstantinou Maria Keramida Eleftherios Panteris Sotiris Kalogeropoulos Neoklis Georgopoulos Fuminori Taniguchi George Adonakis Tasuku Harada Apostolos Kaponis Source Type: research

Illness stress-induced transient hyperglycemia in a patient with a novel YIPF5 homozygous missense variant: expanding the phenotype
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00552-z. Online ahead of print.ABSTRACTA recently described type of neonatal diabetes mellitus is caused by mutations in the YIPF5 gene and is combined with manifestations from the central nervous system, including developmental delay, epilepsy, and microcephaly. The molecular pathophysiology behind this phenotype involves the breakdown of the endoplasmic reticulum stress response due to the loss of protein folding capacity. This results in overt diabetes present from very early in life. Herein, we describe a patient with a newly reported variant in the YIPF5 gene, wh...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Aristeidis Giannakopoulos Dionisios Chrysis Source Type: research

"Female" and "male" hormones in Greek secondary education biology textbooks
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00554-x. Online ahead of print.NO ABSTRACTPMID:38632214 | DOI:10.1007/s42000-024-00554-x (Source: Hormones)
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Anastasia Armeni Georgios Ampatzidis Source Type: research

Once upon a time in Anatolia: the kings with bulging eyes
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00561-y. Online ahead of print.ABSTRACTThe Hittite Empire, formed by the Hittites who settled in central Anatolia at the beginning of the second millennium BC, has left behind rich archeological remains. In this historical review, statues of the Hittite priest-kings, King Idrimi, King Šuppiluliuma, and King Tarhunza, who ruled in these lands in ancient times, are analyzed. Graves' disease (GD) is the most common cause of hyperthyroidism. Patients with GD are also at risk of developing Graves' orbitopathy (GO). Upper eyelid retraction and exophthalmos (bulging eyes) a...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Hulya Elbe Source Type: research

Evaluation of the relation between subclinical systolic dysfunction defined by four-dimensional speckle-tracking echocardiography and growth differentiation factor-15 levels in patients with acromegaly
CONCLUSION: Our study demonstrates that while LVEF was within normal limits, global strain parameters (GLS, GCS, GAS, and GRS) measured by using a novel imaging technique, 4DSTE, were lower in patients with acromegaly, suggesting the presence of subclinical systolic dysfunction in patients with acromegaly. GDF-15 can be a potential predictor of cardiovascular risk in patients with acromegaly.PMID:38632216 | DOI:10.1007/s42000-024-00558-7 (Source: Hormones)
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Busra Firlatan Ugur Nadir Karakulak Vedat Hekimsoy Burcin Gonul Iremli Incilay Lay Deniz Yuce Selcuk Dagdelen Giray Kabakci Tomris Erbas Source Type: research

Illness stress-induced transient hyperglycemia in a patient with a novel YIPF5 homozygous missense variant: expanding the phenotype
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00552-z. Online ahead of print.ABSTRACTA recently described type of neonatal diabetes mellitus is caused by mutations in the YIPF5 gene and is combined with manifestations from the central nervous system, including developmental delay, epilepsy, and microcephaly. The molecular pathophysiology behind this phenotype involves the breakdown of the endoplasmic reticulum stress response due to the loss of protein folding capacity. This results in overt diabetes present from very early in life. Herein, we describe a patient with a newly reported variant in the YIPF5 gene, wh...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Aristeidis Giannakopoulos Dionisios Chrysis Source Type: research

"Female" and "male" hormones in Greek secondary education biology textbooks
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00554-x. Online ahead of print.NO ABSTRACTPMID:38632214 | DOI:10.1007/s42000-024-00554-x (Source: Hormones)
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Anastasia Armeni Georgios Ampatzidis Source Type: research

Once upon a time in Anatolia: the kings with bulging eyes
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00561-y. Online ahead of print.ABSTRACTThe Hittite Empire, formed by the Hittites who settled in central Anatolia at the beginning of the second millennium BC, has left behind rich archeological remains. In this historical review, statues of the Hittite priest-kings, King Idrimi, King Šuppiluliuma, and King Tarhunza, who ruled in these lands in ancient times, are analyzed. Graves' disease (GD) is the most common cause of hyperthyroidism. Patients with GD are also at risk of developing Graves' orbitopathy (GO). Upper eyelid retraction and exophthalmos (bulging eyes) a...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Hulya Elbe Source Type: research

Evaluation of the relation between subclinical systolic dysfunction defined by four-dimensional speckle-tracking echocardiography and growth differentiation factor-15 levels in patients with acromegaly
CONCLUSION: Our study demonstrates that while LVEF was within normal limits, global strain parameters (GLS, GCS, GAS, and GRS) measured by using a novel imaging technique, 4DSTE, were lower in patients with acromegaly, suggesting the presence of subclinical systolic dysfunction in patients with acromegaly. GDF-15 can be a potential predictor of cardiovascular risk in patients with acromegaly.PMID:38632216 | DOI:10.1007/s42000-024-00558-7 (Source: Hormones)
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Busra Firlatan Ugur Nadir Karakulak Vedat Hekimsoy Burcin Gonul Iremli Incilay Lay Deniz Yuce Selcuk Dagdelen Giray Kabakci Tomris Erbas Source Type: research

Thyroid dysfunction due to trace element deficiency-not only selenium but also zinc
CONCLUSION: It is important to consider Se and Zn deficiencies when TSH and FT4 levels are elevated. It should also be noted that transient TSH elevation may be observed with Se supplementation.PMID:38625626 | DOI:10.1007/s42000-024-00550-1 (Source: Hormones)
Source: Hormones - April 16, 2024 Category: Endocrinology Authors: Kohei Nagano Yuma Motomura Hironori Bando Masaaki Yamamoto Keitaro Kanie Kei Yoshino Yushi Hirota Tomoko Yamada Michiko Takahashi Hidenori Fukuoka Wataru Ogawa Source Type: research

Synergistic neuroprotective action of prolactin and 17 β-estradiol on kainic acid-induced hippocampal injury and long-term memory deficit in ovariectomized rats
CONCLUSION: Taken together, these results point to a synergic effect of E2 and PRL in the hippocampus to produce their behavioral, proliferative, and neuroprotective effects.PMID:38625627 | DOI:10.1007/s42000-024-00551-0 (Source: Hormones)
Source: Hormones - April 16, 2024 Category: Endocrinology Authors: Karen De la Torre Marco Antonio Cerb ón Gladys Molina-Salinas Jos é Eduardo Suárez-Santiago Jean-Pascal Morin Gabriel Rold án-Roldán Ofir Picazo Source Type: research

Thyroid dysfunction due to trace element deficiency-not only selenium but also zinc
CONCLUSION: It is important to consider Se and Zn deficiencies when TSH and FT4 levels are elevated. It should also be noted that transient TSH elevation may be observed with Se supplementation.PMID:38625626 | DOI:10.1007/s42000-024-00550-1 (Source: Hormones)
Source: Hormones - April 16, 2024 Category: Endocrinology Authors: Kohei Nagano Yuma Motomura Hironori Bando Masaaki Yamamoto Keitaro Kanie Kei Yoshino Yushi Hirota Tomoko Yamada Michiko Takahashi Hidenori Fukuoka Wataru Ogawa Source Type: research

Synergistic neuroprotective action of prolactin and 17 β-estradiol on kainic acid-induced hippocampal injury and long-term memory deficit in ovariectomized rats
CONCLUSION: Taken together, these results point to a synergic effect of E2 and PRL in the hippocampus to produce their behavioral, proliferative, and neuroprotective effects.PMID:38625627 | DOI:10.1007/s42000-024-00551-0 (Source: Hormones)
Source: Hormones - April 16, 2024 Category: Endocrinology Authors: Karen De la Torre Marco Antonio Cerb ón Gladys Molina-Salinas Jos é Eduardo Suárez-Santiago Jean-Pascal Morin Gabriel Rold án-Roldán Ofir Picazo Source Type: research