The effect of GnRH-a on the angiogenesis of endometriosis

CONCLUSIONS: GnRH-a administration does affect some pathways of angiogenesis in endometriotic lesions, but not all of them. Therefore, supplementary treatments that affect the SP1 pathway of angiogenesis should be developed to enhance the antiangiogenetic effect of GnRH-a in patients with endometriosis.TRIAL REGISTRATION: Clinicaltrial.gov ID: NCT06106932.PMID:38639888 | DOI:10.1007/s42000-024-00559-6

Source: Hormones - April 19, 2024 Category: Endocrinology Authors: Theodoros Filindris Efthymia Papakonstantinou Maria Keramida Eleftherios Panteris Sotiris Kalogeropoulos Neoklis Georgopoulos Fuminori Taniguchi George Adonakis Tasuku Harada Apostolos Kaponis Source Type: research