Increased Th17 and Treg levels in peripheral blood positively correlate with minimal residual disease in acute myeloid leukaemia
CONCLUSION: Increased Th17 and Treg cell levels were positively correlated with onset of AML, poor remission, and MRD.PMID:38682816 | DOI:10.1080/16078454.2024.2346971 (Source: Hematology)
Source: Hematology - April 29, 2024 Category: Hematology Authors: Zhimin Wang Tangxia Liu Yanru Li Zunchang Li Kehong Bi Source Type: research

Combination of venetoclax and azacitidine in relapsed/refractory acute B-cell lymphoblastic leukemia: a case series from a single center
CONCLUSIONS: The combined regimen of venetoclax and azacitidine may be beneficial for patients with R/R B-ALL.PMID:38666535 | DOI:10.1080/16078454.2024.2344998 (Source: Hematology)
Source: Hematology - April 26, 2024 Category: Hematology Authors: Ziyi Hao Yingying Fei Juan Chen Sailan Huang Li Wang Youhuan Yu Meiru Bian Yejun Si Xingxia Zhang Xiaotian Yang Bing Zhang Yan Wan Yanming Zhang Guoqiang Lin Source Type: research

Identification of a novel splice variant in < em > SEC23B < /em > gene in a patient with concomitant presence of congenital dyserythropoietic anemia II and Gilbert's syndrome
CONCLUSION: Identification of the novel splice variant in this study further expands the spectrum of known SEC23B gene mutations. Molecular genetic approaches can lead to accurate diagnosis and management of CDA Ⅱ patients, particularly for those with GS coexisting.PMID:38655690 | DOI:10.1080/16078454.2024.2343163 (Source: Hematology)
Source: Hematology - April 24, 2024 Category: Hematology Authors: Woori Jang Dong Jun Ha Chung Hyun Nahm Jisun Park Su Jin Kim Ji-Eun Lee Yeonsook Moon Source Type: research

Tandem autologous hematopoietic stem cell transplantation for patients with multiple myeloma: a systematic review and meta-analysis
Hematology. 2024 Dec;29(1):2343164. doi: 10.1080/16078454.2024.2343164. Epub 2024 Apr 23.ABSTRACTTo evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of Science and Cochrane Library databases were systematically searched, and 10 eligible studies were included after data extraction and quality evaluation. Meta-analysis showed that compared to single autologous hematopoietic stem cell transplantation, tandem auto-HSCT does not improve OS, EFS or efficacy in MM patients, and may even lead to higher treatment-relate...
Source: Hematology - April 23, 2024 Category: Hematology Authors: Hongtao Li Yaxin Zheng Kehai Gao Chen Tian Source Type: research

Nomogram establishment for short-term survival prediction in ICU patients with aplastic anemia based on the MIMIC-IV database
CONCLUSION: The nomogram model of the short-term survival rate of AA patients was built based on clinical characteristics, and early mechanical ventilation could help improve the short-term survival rate of patients.PMID:38625693 | DOI:10.1080/16078454.2024.2339778 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Yan Tu Jingcheng Zhang Mingzhe Zhao Fang He Source Type: research

Real-world status of treatment for lymphoid neoplasms developed during the course of myeloproliferative neoplasms in Japan
CONCLUSION: Our data indicate that if aggressive lymphoid neoplasms develop during the course of treatment in patients with MPNs, it is acceptable to prioritize chemotherapy for lymphoma.PMID:38626148 | DOI:10.1080/16078454.2024.2340149 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Yoko Edahiro Tomonori Ochiai Yoshinori Hashimoto Michiko Ichii Takeshi Okatani Hiromi Omura Kei Nakajima Makoto Sasaki Jun Ando Tomoiku Takaku Michiaki Koike Koh Izumiyama Junji Hiraga Tomofumi Yano Kensuke Usuki Eiichi Ohtsuka Kenji Yokoyama Tatsuo Oyake Source Type: research

Hb H disease associated with compound heterozygosity for -- < sup > SEA < /sup > deletion and a novel alpha globin chain variant ( < em > HBA2 < /em > :c.175C & gt;A) on the distal histidine in a Chinese family
CONCLUSION: This rare case highlighted the importance of identifying rare haemoglobin variant during prenatal screening. The clinical and genetic data provides useful information on the pathogenicity of this variant and further insight into the role of distal histidine residue of α-globin.PMID:38626234 | DOI:10.1080/16078454.2024.2339559 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Manna Sun Jiwu Lou Wang Xinghe Ying Zhao Yunshi Dai Shuangai Liu Tizhen Yan Source Type: research

Nomogram establishment for short-term survival prediction in ICU patients with aplastic anemia based on the MIMIC-IV database
CONCLUSION: The nomogram model of the short-term survival rate of AA patients was built based on clinical characteristics, and early mechanical ventilation could help improve the short-term survival rate of patients.PMID:38625693 | DOI:10.1080/16078454.2024.2339778 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Yan Tu Jingcheng Zhang Mingzhe Zhao Fang He Source Type: research

Real-world status of treatment for lymphoid neoplasms developed during the course of myeloproliferative neoplasms in Japan
CONCLUSION: Our data indicate that if aggressive lymphoid neoplasms develop during the course of treatment in patients with MPNs, it is acceptable to prioritize chemotherapy for lymphoma.PMID:38626148 | DOI:10.1080/16078454.2024.2340149 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Yoko Edahiro Tomonori Ochiai Yoshinori Hashimoto Michiko Ichii Takeshi Okatani Hiromi Omura Kei Nakajima Makoto Sasaki Jun Ando Tomoiku Takaku Michiaki Koike Koh Izumiyama Junji Hiraga Tomofumi Yano Kensuke Usuki Eiichi Ohtsuka Kenji Yokoyama Tatsuo Oyake Source Type: research

Hb H disease associated with compound heterozygosity for -- < sup > SEA < /sup > deletion and a novel alpha globin chain variant ( < em > HBA2 < /em > :c.175C & gt;A) on the distal histidine in a Chinese family
CONCLUSION: This rare case highlighted the importance of identifying rare haemoglobin variant during prenatal screening. The clinical and genetic data provides useful information on the pathogenicity of this variant and further insight into the role of distal histidine residue of α-globin.PMID:38626234 | DOI:10.1080/16078454.2024.2339559 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Manna Sun Jiwu Lou Wang Xinghe Ying Zhao Yunshi Dai Shuangai Liu Tizhen Yan Source Type: research

Nomogram establishment for short-term survival prediction in ICU patients with aplastic anemia based on the MIMIC-IV database
CONCLUSION: The nomogram model of the short-term survival rate of AA patients was built based on clinical characteristics, and early mechanical ventilation could help improve the short-term survival rate of patients.PMID:38625693 | DOI:10.1080/16078454.2024.2339778 (Source: Hematology)
Source: Hematology - April 16, 2024 Category: Hematology Authors: Yan Tu Jingcheng Zhang Mingzhe Zhao Fang He Source Type: research