Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons
This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8). Morphine sulfate was administered chronically. The treatment groups were given Ach aqueous extract (100, 250, and 500 mg/kg), orally, each day. After 28 days, the Morris water maze test was performed on all subjects. Caspase‑3, Bax, and Bcl‑2 proteins expression in the CA1 region of hippocampal tissue was analyzed usi...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Nazanin Mozafari Jalal Hassanshahi Hamid Ostadebrahimi Ali Shamsizadeh Fatemeh Ayoobi Elham Hakimizadeh Mohammad Pak-Hashemi Ayat Kaeidi Source Type: research
