Whooping Cough (Pertussis) Vaccine Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Coverage with Selected Vaccines and Exemption from School Vaccine Requirements Among Children in Kindergarten - United States, 2022-23 School Year
MMWR Morb Mortal Wkly Rep. 2023 Nov 10;72(45):1217-1224. doi: 10.15585/mmwr.mm7245a2.ABSTRACTU.S. states and local jurisdictions set vaccination requirements for school attendance and conditions and procedures for exemptions from these requirements. States annually report data to CDC on the number of children in kindergarten who meet, are exempt from, or are in the process of meeting requirements. National- and state-level estimates for complete vaccination with measles, mumps, and rubella vaccine (MMR); diphtheria, tetanus, and acellular pertussis vaccine (DTaP); poliovirus vaccine (polio); and varicella vaccine (VAR); ex...
Source: MMWR Morb Mortal Wkl... - November 9, 2023 Category: Epidemiology Authors: Ranee Seither Oyindamola Bidemi Yusuf Devon Dramann Kayla Calhoun Agnes Mugerwa-Kasujja Cynthia L Knighton Source Type: research

Quantitative mechanistic model reveals key determinants of placental IgG transfer and informs prenatal immunization strategies
by Remziye E. Wessel, Sepideh Dolatshahi Transplacental antibody transfer is crucially important in shaping neonatal immunity. Recently, prenatal maternal immunization has been employed to boost pathogen-specific immunoglobulin G (IgG) transfer to the fetus. Multiple factors have been implicated in antibody transfer, but how these key dynamic regulators work together to elicit the observed selectivity is pertinent to engineering vaccines for mothers to optimally immunize their newborns. Here, we present the first quantitative mechanistic model to uncover the determinants of placental antibody transfer and inform personali...
Source: PLoS Computational Biology - November 7, 2023 Category: Biology Authors: Remziye E. Wessel Source Type: research

Antibody and B-cell immune responses against Bordetella pertussis following infection and immunization
J Mol Biol. 2023 Nov 3:168344. doi: 10.1016/j.jmb.2023.168344. Online ahead of print.ABSTRACTNeither immunization nor recovery from natural infection provides life-long protection against Bordetella pertussis. Replacement of a whole-cell pertussis (wP) vaccine with an acellular pertussis (aP) vaccine, mutations in B. pertussis strains, and better diagnostic techniques, contribute to resurgence of number of cases especially in young infants. Development of new immunization strategies relies on a comprehensive understanding of immune system responses to infection and immunization and how triggering these immune components wo...
Source: Mol Biol Cell - November 5, 2023 Category: Molecular Biology Authors: Bahaa Abu-Raya Mirjam J Esser Eve Nakabembe Jes ús Reiné Kyle Amaral Annieck M Diks Esther Imede Sing Sing Way Ali M Harandi Andrew Gorringe Kirsty Le Doare Scott A Halperin Magdalena A Berkowska Manish Sadarangani Source Type: research

Association between women ’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data
ConclusionsThere was no significant association between a woman ’s exposure to domestic violence and whether her child was fully vaccinated. Further work is needed to understand the contextual factors which may explain potential variations between countries. (Source: PLoS One)
Source: PLoS One - November 2, 2023 Category: Biomedical Science Authors: Toluwalogo Daramola Source Type: research

The inclusion of pregnant women in vaccine clinical trials: An overview of late-stage clinical trials' records between 2018 and 2023
This study can inform future demands for increased inclusion, especially in industry-sponsored trials, as it provides an overview of the current vaccine trials scene.PMID:37903681 | DOI:10.1016/j.vaccine.2023.10.057 (Source: Vaccine)
Source: Vaccine - October 30, 2023 Category: Allergy & Immunology Authors: Maha Salloum Antea Paviotti Hilde Bastiaens Jean-Pierre Van Geertruyden Source Type: research

Background rates for severe cutaneous reactions in the US: Contextual support for safety assessment of COVID-19 vaccines and novel biologics
Vaccine. 2023 Oct 25:S0264-410X(23)01208-2. doi: 10.1016/j.vaccine.2023.10.025. Online ahead of print.ABSTRACTThe global COVID-19 public health crisis has resulted in extraordinary collaboration to expeditiously develop vaccines and therapeutics. The safety of these biologics is closely monitored by the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Novel products may have limited safety data, and although serious medical outcomes associated with vaccination are rare, knowledge of background incidence rates of medical conditions in the US population puts reported adverse eve...
Source: Vaccine - October 27, 2023 Category: Allergy & Immunology Authors: Diane Gubernot Mikhail Menis Barbee Whitaker Source Type: research

Burden of hospitalized adult pertussis in France, 2008-2020
Recent epidemiology of pertussis in Europe has showed adults now represent a major proportion of cases. Yet, in most countries, the disease is largely under-recognized in adults and its burden is not well understood. We aimed to estimate the incidence of hospitalized pertussis among adults in France in recent years.This retrospective cohort study among French residents ≥18 years-old over 2008-2020 used the French healthcare claims database (SNDS). Hospitalized pertussis cases were identified by ICD-10 codes A37, stratified by age and presence of asthma and/or chronic obstructive pulmonary disease (COPD) algorithmically ...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Macina, D., Arnaud, M., Despres, J., Antunes, A., Verdier, R., Vargas Zambrano, J. C. Tags: Respiratory infections and bronchiectasis Source Type: research

Routine Vaccination Coverage - Worldwide, 2022
This report reviews trends in World Health Organization and UNICEF immunization coverage estimates at global, regional, and national levels through 2022 and documents progress toward improving coverage with respect to the IA2030 strategy, which aims to reduce the number of children who have not received the first dose of a diphtheria-tetanus-pertussis-containing vaccine (DTPcv1) worldwide by 50% and to increase coverage with 3 diphtheria-tetanus-pertussis-containing vaccine doses (DTPcv3) to 90%. Worldwide, coverage ≥1 dose of DTPcv1 increased from 86% in 2021 to 89% in 2022 but remained below the 90% coverage achieved i...
Source: MMWR Morb Mortal Wkl... - October 26, 2023 Category: Epidemiology Authors: Gurpreet Kaur M Carolina Danovaro-Holliday George Mwinnyaa Marta Gacic-Dobo Lauren Francis Jan Grevendonk Samir V Sodha Ciara Sugerman Aaron Wallace Source Type: research