Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Chronic Inflammation in Age-Related Anemia
In this study, low Hb concentration was observed to be associated with subclinical, chronic inflammation, exhibited by high levels of IL-1β and TNFα. In the large InCHIANTI study, the unexplained anemia cohort (36% of all the anemic population) was found to have higher levels of pro-inflammatory markers and higher resistance of bone marrow erythroid progenitors to erythropoietin compared to non-anemic controls. The mechanisms underlying low Hb levels in older adults are multifactorial and complex. Our study suggested that the underlying mechanisms involve subclinical chronic low-grade inflammation, bone marrow resistance...
Source: Fight Aging! - June 8, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Masked Hypertension: Your Silent Health Threat
Conclusion
Masked hypertension is a silent threat that occurs when normal blood pressure readings at the doctor’s office conceal high readings at home or elsewhere.
Although the precise cause remains uncertain, factors like smoking, excessive alcohol, and work-related stress appear to play a role.
Despite the symptomless nature of this condition, regular monitoring of blood pressure can help detect and manage it effectively, preventing serious complications.
Regular lifestyle modifications and prescribed medications can help keep this masked menace at bay.
References
Cuspidi, C., et al. (2023). Masked hy...
Source: The EMT Spot - May 30, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Health Equity In The AI And Digital Health Era: Promise or Peril?
This report estimated that poor health reduces global GDP by 15% each year.
On the flip side, equalizing healthcare access and quality has healthful effects on the economy at large. Digital technology could narrow the health equity gap by simplifying complex medical processes and removing travel barriers to healthcare access.
Figures indicate that underrepresented and/or disadvantaged (poor, rural, minority, women, LGBTQ, etc) groups have significantly less access to all the cutting-edge solutions digital health offers. Thus the gap is not only not closing, but it’s rather further widening right now.
W...
Source: The Medical Futurist - May 30, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine Health Sensors & Trackers Personalized Medicine Telemedicine & Smartphones digital health literacy health equity digital health equity AI Source Type: blogs
Can You Take Birth Control Pills With Hypertension?
Navigating birth control options when living with hypertension can be challenging. This comprehensive overview explores the complex relationship between birth control pills and high blood pressure, addressing scientific research, potential risks, and viable alternatives. It underscores the importance of personalized medical advice in making safe and informed contraceptive choices.
Quick Summary
Combined oral contraceptives can potentially raise blood pressure levels, making them a risk for women already diagnosed with hypertension.
Alternatives such as progestin-only pills, IUDs, barrier methods, and contrace...
Source: The EMT Spot - May 25, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Can You Donate Blood With Hypertension?
Conclusion
In conclusion, high blood pressure doesn’t exclude you from the act of donating blood.
It’s all about ensuring your blood pressure is well-controlled and taking the necessary precautions before and during the process.
As the World Health Organization notes:
“Every blood donor is a life saver”.
And that journey of saving lives starts with taking good care of your own health.
References
Requirements by Donation Type: https://www.redcrossblood.org/donate-blood/how-to-donate/eligibility-requirements.html
Blood safety and availability: https://www.who.int/news-room/fa...
Source: The EMT Spot - May 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
AI is Bright, But Can Also Be Dark
BY KIM BELLARD
If you’ve been following artificial intelligence (AI) lately – and you should be – then you may have started thinking about how it’s going to change the world. In terms of its potential impact on society, it’s been compared to the introduction of the Internet, the invention of the printing press, even the first use of the wheel. Maybe you’ve played with it, maybe you know enough to worry about what it might mean for your job, but one thing you shouldn’t ignore: like any technology, it can be used for both good and bad.
If you thought cyberattacks/cybercrimes were bad when done by human...
Source: The Health Care Blog - May 23, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Artificial intelligence Dark Web DarkBERT Kim Bellard Source Type: blogs
Should doctors prescribe lecanemab (Leqembi) to women? The answer, given available evidence, is probably No
This article is an edited combination of two previous blog posts by him at www.skin2neuron.org.
News in Context:
CMS: anti-amyloid drug Leqembi (lecanemab) doesn’t meet the “reasonable and necessary” standard required for wider Medicare coverage
The post Should doctors prescribe lecanemab (Leqembi) to women? The answer, given available evidence, is probably No appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - May 10, 2023 Category: Neuroscience Authors: Prof. Michael Valenzuela Tags: Brain/ Mental Health amyloid amyloid antibodies amyloid removal CLARITY trial Clinical Dementia Rating immunotherapy lecanemab Leqembi women Source Type: blogs
Long Phone Calls Linked To Hypertension: Surprising Risk Revealed
Conclusion
This study suggests that talking on mobile phones for more than 30 minutes per week may increase the risk of developing hypertension.
While more research is needed to validate these findings, it is wise to be mindful of our mobile phone usage and prioritize heart health.
As Dr. Xianhui Qin recommended, reducing the time spent on phone calls could be a crucial step towards preserving our heart health.
References
Ye Z, Zhang Y, Zhang Y, et al. Mobile phone calls, genetic susceptibility and new-onset hypertension: results from 212,046 UK Biobank participants. Eur Heart J Digit Health. 2023. doi:10.109...
Source: The EMT Spot - May 7, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Fight Aging! Newsletter, May 8th 2023
In conclusion, NAT mitigated age-associated cerebral injury in mice through gut-brain axis. The findings provide novel evidence for the effect of NAT on anti-aging, and highlight the potential application of NAT as an effective intervention against age-related diseases.
Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study
https://www.fightaging.org/archives/2023/05/retinal-cell-reprogramming-restores-vision-in-non-human-primate-study/
Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system...
Source: Fight Aging! - May 7, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A List of Trials of Stem Cell Therapies Aimed at Slowing Aging
To what degree can the current panoply of stem cell therapies slow the progression of aging? A great many trials have been conducted, largely of cell therapies wherein the principle mode of action is reduction of chronic inflammatory signaling. This has value, but it remains the case that the original vision of greatly enhanced regeneration and transplanted cells surviving to support tissue for the long term has yet to be realized. The paper here provides a concrete list of trials and various different strategies for the production of first generation stem cell therapies; good reading for those interested in seeking out th...
Source: Fight Aging! - May 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Finally A Good Wearable Blood Pressure Monitor: Aktiia Bracelet Review
The digital health revolution has been lagging behind in at least one major field: blood pressure monitoring. For a very long time, there were no better solutions in the market than traditional cuffs. Even the first smartwatches (like the one I tested from Omron), were big and uncomfortable to wear. So it was time for companies to realise the future of BP monitoring lies in Photoplethysmography (PPG).
PPG is a non-invasive optical technique used to measure blood volume changes in the microvascular bed of tissue. It works by shining a light onto the skin and then measuring the variations in light intensity that result fr...
Source: The Medical Futurist - May 2, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Health Sensors & Trackers Aktiia review blood pressure wearable blood pressure monitor non-invasive blood pressure monitor blood pressure bracelet digital health sensors Source Type: blogs
Weekly Roundup – April 22, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week.
Hal Wolf on HIMSS 2023: “It Feels Like We Are All Back.” In a press briefing, the HIMSS CEO said attendance for this year’s event is 35,000 – less than 2019 but a significant increase from 2021 and 2022. Wolf also briefly discussed how HIMSS would continue to invest in emerging markets and build its ongoing relationship with the World...
Source: EMR and HIPAA - April 22, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs
Can Negotiations at the World Health Organization Lead to a Just Framework for the Prevention, Preparedness and Response to Pandemics as Global Public Goods?
Viviana Munoz Tellez (South Centre), Can Negotiations at the World Health Organization Lead to a Just Framework for the Prevention, Preparedness and Response to Pandemics as Global Public Goods? (2022): This paper advances that WHO Member States, having agreed to... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - April 9, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Aiberry Secures $8M in Seed Funding to Accelerate AI-Powered Mental Health Screenings
CCG-led round will be used to drive rapid adoption of new digital platform that eliminates inaccuracy and bias in identification of people suffering from mental health disorders
Artificial intelligence (AI)-powered mental health screening pioneer Aiberry (pronounced “I” + “berry”) today announced that it has secured $8 million in seed funding led by Confluence Capital Group, Inc. (CCG) with participation from the VC fund Ascension AI. The new funds, which bring total funding to $10M, will be used to accelerate adoption of the Aiberry platform, which uses an AI-powered therapeutic assistant to conduct a conversatio...
Source: EMR and HIPAA - March 16, 2023 Category: Information Technology Authors: Healthcare IT News Tags: AI/Machine Learning Health IT Company Healthcare IT Aiberry Artificial Intelligence Ascension AI CCG Confluence Capital Group Confluence Capital Group Inc. Dr. Newton Howard Dr. Tammy Malloy Futures Recovery Healthcare Georgetown U Source Type: blogs
