In the wake of the pandemic: preparing for long Covid
World Health Organization Europe -This policy brief highlights areas where policy-makers can take action to meet the challenge of post-Covid conditions based on what is currently known. It addresses the need for multidisciplinary, multispecialty approaches to assessment and management; development of new care pathways and contextually appropriate guidelines for health professionals; and the creation of appropriate services, including rehabilitation and online support tools.Policy briefWorld Health Organization Europe - news (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - February 25, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Covid-19 Source Type: blogs

The Feds ’ Sorry Record on COVID-19
David BoazThey say journalism is the first rough draft of history. With the Covid pandemic now a year old, we are starting to seebooks on the topic. And variouslibertarianstudies andarticles, critically examining government andprivate-sector responses to the crisis, have appeared. But some of those rough drafts in the major media add up to a pretty strong critique of government failure by themselves. Just consider the disappointing, even tragic, analyses that have been appearing over the past year:The federal government hadreports andwarnings andwar games aboutpandemic danger at least as far back as 2001, butwas apparently...
Source: Cato-at-liberty - February 24, 2021 Category: American Health Authors: David Boaz Source Type: blogs

Fight Aging! Newsletter, February 22nd 2021
In conclusion, long term LRIC could decrease blood pressure and ameliorate vascular remodeling via inflammation regulation. The Damage of a Heart Attack Causes the Immune System to Overreact https://www.fightaging.org/archives/2021/02/the-damage-of-a-heart-attack-causes-the-immune-system-to-overreact/ Researchers here note a mechanism that causes T cells of the adaptive immune system to spur chronic inflammation and tissue damage following a heart attack. As the researchers note, not all inflammation is the same. Some is maladaptive, and this is particularly the case in older individuals. The aged immun...
Source: Fight Aging! - February 21, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

New drug development: the case of antibiotics
This article in Clinical Infectious Diseases explains the problem and also why drug companies are not doing enough to develop new classes of antibotics.Antimicrobial resistance is a profound global health threat of the 21st century. The United Kingdom ’s AMR Review estimates that by 2050 as many as 10 million persons a year will die of drug-resistant infections if solutions are not found [1]. The World Bank projects that, without containment of antimicrobial resistance, annual global gross domestic product will decrease by 1%, that is,>$1 trillion annually from 2030, and the hardest hit will be persons in low-income c...
Source: Stayin' Alive - February 19, 2021 Category: American Health Source Type: blogs

Grandparenting: Anticipating March 11
March 11th, 2020 — or was it March 12th, or a few days before or beyond that? Each of us has a date and time etched in our minds when we knew that the COVID-19 pandemic was upon us. Now, the anniversary of that date is fast approaching. What, if anything, do we do to mark it? And how do we convey our thoughts and feelings about this milestone to our grandchildren? Anyone who has reached grandparenthood has collected anniversaries along the way. There are anniversaries of joyful occasions, and ones that serve as painful reminders of loss. There are the personal anniversaries — the births and deaths of loved ones — and...
Source: Harvard Health Blog - February 15, 2021 Category: Consumer Health News Authors: Ellen S. Glazer, LICSW Tags: Adolescent health Children's Health Mental Health Parenting Relationships Source Type: blogs

Immunosenescence and COVID-19
It is very clear from the data, as is the case for influenza, the mortality of the COVID-19 pandemic is suffered near entirely by the old. This is because the aged immune system is less capable of fighting off pathogens, but also because the state of chronic inflammation and other dysfunctions resulting from immune system aging makes the cytokine storm of a severe SARS-Cov-2 viral infection that much more likely and that much more severe. Patients with inflammatory age-related conditions, or conditions associated with obesity, a prominent cause of chronic inflammation, are much more likely to die from SARS-Cov-2 infection....
Source: Fight Aging! - February 15, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The World Health Organization in Global Health Law
Benjamin Mason Meier (University of North Carolina), Allyn Taylor (University of Washington), Mark Eccleston-Turner (Keele University), Roojin Habibi (York University), Sharifah Sekalala (University of Warwick), Lawrence O. Gostin (Georgetown University), The World Health Organization in Global Health Law, 48(4) J.... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - February 14, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

A health librarian at church: clean hands
At church, we had alreadytwinned our toilets through Tear Fund.   So our loos have a picture of our twin toilet, and the church gave money to Tear Fund for the work their partner churches to do provide toilets in areas that do not have them, and health education materials so that people know the health benefits of using them.And nowHillsborough Tabernacle in Sheffield hastwinned its taps, to provide clean running water to a community that has none.  Washing your hands frequently, as per COVID guidance, is of course impossible if you have no clean water.  And if you don ' t, of course, tha...
Source: Browsing - February 13, 2021 Category: Databases & Libraries Tags: water Source Type: blogs

Fight Aging! Newsletter, February 1st 2021
In this study, we characterize age-related phenotypes of human hematopoietic stem cells (HSCs). We report increased frequencies of HSC, hematopoetic progenitor cells (HPC), and lineage negative cells in the elderly but a decreased frequency of multi-lymphoid progenitors. Aged human HSCs further exhibited a delay in initiating division ex vivo though without changes in their division kinetics. The activity of the small RhoGTPase Cdc42 was elevated in aged human hematopoietic cells and we identified a positive correlation between Cdc42 activity and the frequency of HSCs upon aging. The frequency of human HSCs polar fo...
Source: Fight Aging! - January 31, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

One Cannot be " Fat But Healthy "
Extensive human evidence strongly supports the conjecture that excess fat tissue is simply harmful. That harm cannot be evaded by exercise: one cannot be "fat but healthy". Visceral fat packed around the abdominal organs generates chronic inflammation, a raised burden of senescent cells, and all sorts of other issues. It pushes fat into the organs themselves; in the case of the pancreas that excess fat is the primary cause of type 2 diabetes. In the liver, it leads to fatty liver disease. Even modest amounts of excess fat tissue raise mortality rates and shorten life expectancy. A large study finds that physical a...
Source: Fight Aging! - January 29, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Understanding Leprosy on World Leprosy Day
Leprosy is a chronic and progressive disease that primarily affects the skin and peripheral nervous system. Leprosy has been with us for thousands of years. There is evidence of the disease as far back as 4000 BC, in ancient Egypt.[1] In 1873, Norwegian physician Dr. Gerhard Armauer Hansen discovered that leprosy was caused by a bacterium. [2] Today, we call this bacterium Mycobacterium leprae, and we often refer to leprosy as Hansen’s Disease, in honor of Dr. Hansen. While leprosy caused significant morbidity and mortality in the past, cases today are rare and are curable with proper treatment. How Is Leprosy Transmitte...
Source: GIDEON blog - January 28, 2021 Category: Databases & Libraries Authors: Uri Blackman Tags: News Leprosy Source Type: blogs

UK vaccination policy
House of Commons Library - This briefing provides an overview of UK vaccination policy. It includes an introduction to the science of vaccination and covers UK vaccination programmes, as well as considering the response of the government to the UK's loss of the World Health Organization's measles elimination status. BriefingSummary (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - January 21, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Public health and health inequalities Source Type: blogs

Fight Aging! Newsletter, January 18th 2021
In this study, Desferal, deferoxamine mesylate for injection, which is approved for the treatment of acute iron intoxication and chronic iron overload, was used to explore the beneficial effects on preventing aging-induced bone loss and mitigating dysfunction of aged BMSCs. High-dose Desferal significantly prevented bone loss in aged rats. Compared with controls, the ex vivo experiments showed that short-term Desferal administration could promote the potential of BMSC growth and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs and revise the expression of stemness/se...
Source: Fight Aging! - January 17, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

All you need to know about waterborne diseases
  Waterborne diseases are contracted through exposure to contaminated water including drinking water, water used in food preparation, and swimming water.  They can be caused by bacteria, viruses, and parasites. Below is a partial list of waterborne disease pathogens, their microbial classification, and their resulting illnesses. Classification Microorganism Disease Bacterium Campylobacter spp. Campylobacteriosis Bacterium Escherichia coli E. Coli Diarrhea Bacterium Legionella pneumophila Legionnaires’ Disease Bacterium Salmonella enterica Salmonellosis Bacterium Salmonella typhi Typhoid fever ...
Source: GIDEON blog - January 14, 2021 Category: Databases & Libraries Authors: Kristina Symes Tags: Microbiology News Tips Source Type: blogs

Thoughts on the Road to Greater Human Longevity
I recently noticed this scientific commentary, published in a journal not specifically focused on aging. The author is far from the only person to have noticed that priorities in medical research and development do not seem to match up with the major causes of death all that well. It can't hurt to keep on pointing out that research into the most harmful biological processes in the world, meaning the mechanisms that cause aging, is very poorly funded and investigated in comparison to the vast and ongoing toll of death that results. Until aging is defeated, more funding for research into rejuvenation therapies will continue ...
Source: Fight Aging! - January 12, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs