Development and Function of Dendritic Cells in the Immune Response
Immunonology IG Seminar Dr. Ken Murphy obtained his MD and PhD from the Johns Hopkins University School of Medicine. In 1984, he began a residency in Pathology at Washington University School of Medicine in St. Louis. After this, he did postdoctoral work in molecular immunology with Dr. Dennis Loh, where he generated the DO11.10 TCR transgenic mouse used in studies of self-tolerance, and later in studies of Th1/Th2 development. In 1990, he joined the Pathology and Immunology Department at Washington University, where he is now full professor and an investigator of the Howard Hughes Medical Institute. His work has focused o...
Source: Videocast - All Events - April 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Butterfly cam catches cancer!
NSFfunded researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis have developed a surgical camera inspired by the eye of the Morpho butterfly to more accurately find lurking cancer.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - April 26, 2018 Category: Science Source Type: video

Macrophages and lymphatics: guardians of the tissue microenvironment
Immunonology IG Seminar Gwen Randolph received her PhD in Cellular and Molecular Pathology from SUNY, Stonybrook, and completed post-doctoral training at the Rockefeller University and Cornell University Medical Center under the mentorship of Ralph Steinman and William Muller. She joined the faculty at Cornell/Weill Medical College Cornell, and then spent 11 years at Mount Sinai School of Medicine, before moving to Washington University in 2011, where she is now an endowed professor, and head of the immunology graduate program in the Department of Pathology and Immunology. Dr. Randolph has made many major contributions to ...
Source: Videocast - All Events - February 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Translating from Chemistry to Clinic with Deep Learning
NLM Informatics and Data Science Lecture Series Many medicines become toxic only after bioactivation by metabolizing enzymes. Often, metabolic enzymes transformed them into chemically reactive species, which subsequently conjugate to proteins and cause adverse events. For example, carbamazepine is epoxidized by P450 enzymes in the liver, but then conjugates to proteins, causing Stevens Johnson Syndrome in some patients. The most difficult to predict drug reactions, idiosyncratic adverse drug reactions, often depend on bioactivation. Our group has been using deep learning to model the metabolism of diverse chemicals, and th...
Source: Videocast - All Events - February 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Secrets of butterfly wings revealed!
How do genes shape and color a butterfly’s wings? George Washington University evolutionary geneticist Arnaud Martin is using CRISPR Cas9, a gene editing technique, to determine how changes in the 'painting gene' WntA result in different wing shapes and patterns in butterflies. This research ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - December 21, 2017 Category: Science Source Type: video

Exposure to language improves "invented spellings" of children ages 3 to 5 years
New research from Washington University in St. Louis suggests that children as young as 3 already are beginning to recognize and follow important rules and patterns governing how letters in the English language fit together to make words. The study provides new evidence that children start to ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - August 11, 2017 Category: Science Source Type: video

The gut microbiome: a master regulator of metabolism
Immunology Interest Group Seminar Series Humans and many other animals are home to enormous numbers of beneficial bacteria that profoundly influence health. The existence of beneficial resident microorganisms was first recognized in the late 1800's by Louis Pasteur, who founded the field of medical microbiology. However, we ’ ve only recently begun to acquire a molecular understanding of how resident microorganisms contribute to our health. The Hooper lab has spent more than a decade studying how resident bacteria of the gut communicate with our own cells to shape our physiology, our development, and our ability to fight...
Source: Videocast - All Events - March 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Brain imaging links Alzheimer’s decline to tau protein
Scientists at Washington University are collaborating with the pharmaceutical companies AbbVie, Biogen and Eli Lilly & Company to investigate the buildup and clearance of tau protein in the brains of patients with Alzheimer’s disease. The positron emission tomography image on the left shows the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - January 25, 2017 Category: Science Source Type: video

DDM Seminar Series: How to Say Anything to Anyone
Deputy Director for Management (DDM) Seminar Series The first installment of the FY2017 DDM Seminar Series. To receive credit for watching the LIVE Videocast, you need to register for the event in LMS on the morning of the event. Archived Videocast registration is also available in LMS approximately 10 days after the event. This first seminar features Shari Harley presenting on candor, and how to say anything to anyone and have it be easy. Shari Harley, MA and Certified Speaking Professional, is the founder and president of Candid Culture, an international training and consulting firm helping corporations, associations, go...
Source: Videocast - All Events - December 5, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

New Insights into Flavivirus Pathogenesis and Immunity: Yes, that Includes Zika Virus.
Dr. Michael Diamond received a B.A. degree in political science at Columbia University before pursuing medical and graduate training at Harvard School of Medicine. As a graduate student, he investigated the regulation of the integrin Mac-1 (CD11b/CD18) in the laboratory of Dr. Timothy Springer. He did a residency and a clinical fellowship in infectious diseases at the University of California, San Francisco, and most of his post-doctoral training in the laboratory of Dr. Eva Harris at the University of California, Berkeley. He was recruited to Washington University in St. Louis as an Assistant Professor in 2001 and is now ...
Source: Videocast - All Events - May 20, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Hijacking the Hematopoietic System and Other Dirty Tricks that Breast Cancers Play
NCI’s Center for Cancer Research (CCR) Grand Rounds Dr. McAllister is an Associate Scientist in the Hematology Division at Brigham & Women’s Hospital and an Assistant Professor of Medicine at Harvard Medical School in Boston. She received her undergraduate degree at the University of Michigan in Ann Arbor and completed her Ph.D. studies in molecular and cellular biology at Washington University School of Medicine in St. Louis. She joined Robert Weinberg’s laboratory at the Whitehead Institute for Biomedical Research as a postdoctoral fellow where she established new pre-clinical models to study breast cancer pa...
Source: Videocast - All Events - May 9, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Translating the cancer genome: transforming cancer care
Presented by: Elaine R. Mardis, Ph.D., Washington University School of MedicineCategory: WALS - Wednesday Afternoon LecturesAired date: 03/30/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - April 1, 2016 Category: Journals (General) Tags: Past Events Source Type: video

Introduction to the Principles and Practice of Clinical Research (IPPCR): Study Budget Development
Presented by: Phyllis Klein, R.N., C.C.R.C., B.S.N., Director, Regulatory Support and Compliance, Washington University in St. LouisCategory: IPPCRAired date: 03/21/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 22, 2016 Category: Journals (General) Tags: Past Events Source Type: video

Role and Regulation of the NLRP3 Inflammasome.
Immunology Interest Group Gabriel Nuñez earned his M.D. degree from the University of Seville, Spain, in 1977. He received postdoctoral training in Immunology at the University of Texas Southwestern Medical Center, Dallas (1979–1984) and residency training in Anatomical Pathology at Washington University in St Louis (1985–1990). In 1987, he joined the laboratory of Stanley Korsmeyer at Washington University, where he studied the function of the anti-apoptotic protein BCL-2. In 1991, he joined the Department of Pathology at the University of Michigan in Ann Arbor as an Assistant Professor and was promoted to full Prof...
Source: Videocast - All Events - March 14, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Three Decades of Neuroscience, Glutamate Receptor Channels
Three Decades of Neuroscience on Glutamate Receptor Channels 9:30 a.m. Welcome and Opening Remarks9:35 a.m. "Who knew NMDA Receptors did this....." Gary Westbrook, M.D., Senior Scientist and Co-Director, Vollum Institute, Oregon Health and Science University10:05 a.m. “Too many Potassium Channels”Bruce Bean, Ph.D., Robert Winthrop Professor of Neurobiology, Department of Neurobiology, Harvard Medical School10:35 a.m. “Glutamate Receptor Pores”James Huettner, Ph.D., Professor, Department of Cell Biology and Physiology, Washington University in St. Louis11:05 a.m. Break11:30 a.m. “NMDA Receptors: Presynaptic, ...
Source: Videocast - All Events - November 13, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video