New Insights into Flavivirus Pathogenesis and Immunity: Yes, that Includes Zika Virus.

Dr. Michael Diamond received a B.A. degree in political science at Columbia University before pursuing medical and graduate training at Harvard School of Medicine. As a graduate student, he investigated the regulation of the integrin Mac-1 (CD11b/CD18) in the laboratory of Dr. Timothy Springer. He did a residency and a clinical fellowship in infectious diseases at the University of California, San Francisco, and most of his post-doctoral training in the laboratory of Dr. Eva Harris at the University of California, Berkeley. He was recruited to Washington University in St. Louis as an Assistant Professor in 2001 and is now a full Professor with tenure. He is the co-director of the Midwest Regional Center for Excellence in Biodefense and Emerging Infectious Diseases Research and Head of the Division of Infectious Diseases and Vaccine Development, Center for Human Immunology and Immunotherapy Programs. Dr. Diamond leads an extremely productive and interdisciplinary research program focused on the pathogenesis of and immunity to viral infections. These efforts may be divided generally into i.) studies of the mechanisms of antiviral humoral immunity (West Nile virus, Dengue virus, Chikungunya virus and most recently Zika virus) and ii.) innate responses to viral infection. With respect to the former, his group has made significant contributions to understanding the humoral immunity using animal models of flavi- and alphavirus infections (e.g. Purtha, JEM, 2011) and mechanisms of...
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