Characteristics of TB cases without documented sputum culture in the United States, 2011 & #8211;2021
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - April 26, 2024 Category: Respiratory Medicine Authors: Rautman, L.H. Kammerer, J.S. Silk, B.J. Marconi, V.C. Youngblood, M.E. Edwards, J.A. Wortham, J.M. Self, J.L. Tags: ORIGINAL ARTICLES Source Type: research

News at a glance: Plants ’ tree of life, conserving U.S. federal lands, and entertaining invertebrate sentience
CONSERVATION Interior Department boosts restoration The largest manager of public lands in the United States last week announced it will manage them to promote ecological stewardship, while continuing to allow extractive commercial uses such as mining, oil drilling, and cattle grazing. The Bureau of Land Management (BLM) oversees nearly 1 million square kilometers of federal land, about 10% of the country’s landmass, mostly in Western states. Under a rule issued on 18 April, BLM will now assess the ecological condition of all hectares it manages , not just grazing land. The agency will a...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research

Can science find ways to ease loneliness?
Related podcast The science of loneliness, making one of organic chemistry’s oldest reactions safer, and a new book series BY Sarah Crespi , Kelly Servick , Ariana Remmel , Valerie Thompson , Angela Saini Podcast 25 Apr 2024 One Wednesday in May 2023, a small group gathered at an outdoor café in Barcelona, Spain, sipping coffee in t...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research

The Diversity of Institutions Conducting Biomedical Research
Perspect Biol Med. 2023;66(1):58-88. doi: 10.1353/pbm.2023.0004.ABSTRACTBiomedical research in the United States has contributed enormously to science and human health and is conducted in several thousand institutions that vary widely in their histories, missions, operations, size, and cultures. Though these institutional differences have important consequences for the research they conduct, the organizational taxonomy of US biomedical research has received scant systematic attention. Consequently, many observers and even participants are surprisingly unaware of important distinguishing attributes of these diverse institut...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Jeffrey S Flier Source Type: research

Science in the Public Mind: < em > sources and consequences of antipathy < /em >
Perspect Biol Med. 2023;66(3):468-477. doi: 10.1353/pbm.2023.a902039.ABSTRACTPublic attitudes toward science in the United States can profoundly affect national well-being, and even national security. We live in a time when these attitudes are considerably more negative than usual. This critical assessment identifies a number of contributors to public antipathy toward science, some of which are intrinsic to the nature of science and as old as science itself, and some of which are external to science, have arisen recently, and may be unique to the present. Historic examples of scientific developments and challenges and two ...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: William H Woodruff Source Type: research

Telemedicine Screening for Eye Disorders in Federally Qualified Health Centers: Relationship to Vision-Targeted Health-Related Quality of Life
Conclusion: Vision-targeted, health-related quality of life in our FQHC settings was related to the visual acuity impairment and the diagnosis of diabetic retinopathy but was also influenced by a variety of sociodemographic factors.PMID:38662523 | DOI:10.1089/tmj.2023.0695 (Source: Rural Remote Health)
Source: Rural Remote Health - April 25, 2024 Category: Rural Health Authors: Thomas A Swain Gerald McGwin Christopher A Girkin Cynthia Owsley Source Type: research

A framework for understanding the human experience of nature through cognitive mapping
Conserv Biol. 2024 Apr 25:e14283. doi: 10.1111/cobi.14283. Online ahead of print.ABSTRACTHuman behavior is a key driver of the biodiversity crisis, and addressing it requires changing individual choices and actions. Yet, the same processes that imperil biodiversity (e.g., urbanization) also alienate people from the experience of nature, eroding care for the natural world. Although averting this extinction of experience is increasingly recognized as a major contemporary conservation challenge, understanding of what constitutes nature experience remains elusive and few empirical studies have explored it directly. Most resear...
Source: Conservation Biology - April 25, 2024 Category: Biology Authors: Nitzan Dan-Rakedzon Whitney Fleming Nurit Lissovsky Susan Clayton Assaf Shwartz Source Type: research

Exploring potential developmental origins of common neurodegenerative disorders
Biochem Soc Trans. 2024 Apr 25:BST20230422. doi: 10.1042/BST20230422. Online ahead of print.ABSTRACTIn the United States, it is now estimated that 6.7 million people over the age of 65 are afflicted by Alzheimer's disease (AD), over 1 million people are living with Parkinson's disease (PD), and over 200 000 have or are at risk for developing Huntington's disease (HD). All three of these neurodegenerative diseases result in the ultimate death of distinct neuronal subtypes, and it is widely thought that age-related damage is the single biggest contributing factor to this neuronal death. However, recent studies are now sugges...
Source: Biochemical Society Transactions - April 25, 2024 Category: Biochemistry Authors: James P Catlin Christine E Schaner Tooley Source Type: research

Maternal red blood cell alloimmunization prevalence in the United States
This study describes prevalence and trends in alloimmunization in pregnancy in the U.S. RBC antibodies (abs) were identified in a large, nationwide, commercial laboratory database from 2010-2021. The cohort comprised pregnancies for which the year of lab collection and patient's state of residence were available. Data were normalized based on U.S. Centers for Disease Control and Prevention estimates of live births and weighted by year and U.S. Census Division. Cochrane-Armitage tests assessed temporal trends of alloimmunization. Of 9,876,196 pregnancies, 1.5% (147,262) screened positive for RBC abs, corresponding to an est...
Source: Adv Data - April 25, 2024 Category: Epidemiology Authors: Ronan P Sugrue Kenneth J Moise Jerome J Federspiel Elizabeth Abels Judy Z Louie Zhen Chen Lance A Bare Damian P Alagia Harvey W Kaufman Source Type: research

Use of an Additional Updated 2023-2024 COVID-19 Vaccine Dose for Adults Aged ≥65 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024
MMWR Morb Mortal Wkly Rep. 2024 Apr 25;73(16):377-381. doi: 10.15585/mmwr.mm7316a4.ABSTRACTCOVID-19 remains an important public health threat, despite overall decreases in COVID-19-related severe disease since the start of the COVID-19 pandemic. COVID-19-associated hospitalization rates remain higher among adults aged ≥65 years relative to rates in younger adults, adolescents, and children; during October 2023-January 2024, 67% of all COVID-19-associated hospitalizations were among persons aged ≥65 years. On September 12, 2023, CDC's Advisory Committee on Immunization Practices (ACIP) recommended updated (2023-2024 For...
Source: MMWR Morb Mortal Wkl... - April 25, 2024 Category: Epidemiology Authors: Lakshmi Panagiotakopoulos Monica Godfrey Danielle L Moulia Ruth Link-Gelles Christopher A Taylor Kevin Chatham-Stephens Oliver Brooks Matthew F Daley Katherine E Fleming-Dutra Megan Wallace Source Type: research

QuickStats: Percentage* of Employed Adults Aged ≥18 Years Who Slept & lt;7 Hours per 24-Hour Period, < sup > † < /sup > by Sex and Number of Work Hours per Week < sup > § < /sup > - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Apr 25;73(16):385. doi: 10.15585/mmwr.mm7316a6.NO ABSTRACTPMID:38662669 | DOI:10.15585/mmwr.mm7316a6 (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - April 25, 2024 Category: Epidemiology Source Type: research

Recent clinical trials and optical control as a potential strategy to develop microtubule-targeting drugs in colorectal cancer management
World J Gastroenterol. 2024 Apr 7;30(13):1780-1790. doi: 10.3748/wjg.v30.i13.1780.ABSTRACTColorectal cancer (CRC) has remained the second and the third leading cause of cancer-related death worldwide and in the United States, respectively. Although significant improvement in overall survival has been achieved, death in adult populations under the age of 55 appears to have increased in the past decades. Although new classes of therapeutic strategies such as immunotherapy have emerged, their application is very limited in CRC so far. Microtubule (MT) inhibitors such as taxanes, are not generally successful in CRC. There may ...
Source: World Journal of Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Katsuhiro Kita Allen Burdowski Source Type: research

Contemporary Outcomes and Patterns of Injury Associated With Parachuting Accidents
DISCUSSION: Although the 30-day mortality rate for patient who presented to our trauma center is low, it can bear significant risks including major injury. The most common injuries were lower extremity and spinal in origin with a third of patients overall requiring at least one operation.PMID:38661105 | DOI:10.1177/00031348241248809 (Source: The American Surgeon)
Source: The American Surgeon - April 25, 2024 Category: Surgery Authors: Ramsey S Elsayed Avian Pham Nikilish Chitibomma Macey Yates Kaylene Barrera Marvin J Atchison Titio F Gorski Source Type: research

Latinx Youth's Mental Health Needs and Socioeconomic Factors Associated with Service Utilization
This study examined mental health needs and risk factors associated with service use among Latinx high school students in two cities in the United States. We explored how socioeconomic characteristics, school location, youth and parental nativity, and self-perceived clinical needs were associated with the odds of youths seeing a mental health provider. Data were collected from 306 Latinx youths during the 2018-19 school year. Most youths (78%) self-reported symptoms of anxiety, trauma, or depression above the clinical range. None of these clinical needs predicted service utilization. Youth experiencing less economic hardsh...
Source: Journal of Health Care for the Poor and Underserved - April 25, 2024 Category: International Medicine & Public Health Authors: Natalia Giraldo-Santiago Arlene Bjugstad Jodi Berger Cardoso Tzuan A Chen Kalina Brabeck Ruth M L ópez Source Type: research

Immigrant Mothers' Perspectives on Pediatric Primary Care: Challenges and Solutions to Improve Medical Home Use
J Health Care Poor Underserved. 2024;35(1):299-315.ABSTRACTChildren in immigrant families (CIF) constitute 25% of all children in the United States. Known barriers to accessing and navigating the health care system for immigrants (i.e., poverty, fear, limited English proficiency, lack of insurance) lead to decreased medical home establishment among CIF, although the ways in which these obstacles affect medical home access are less studied. With a focus on Congolese, Afghan, Syrian/Iraqi, and Central American immigrants, key informant interviews and focus groups were conducted to identify mothers' perceptions of and experie...
Source: Journal of Health Care for the Poor and Underserved - April 25, 2024 Category: International Medicine & Public Health Authors: Tricia Francisco Wagner Allison Olmsted Kimberly Kay Lopez Karla Fredricks Source Type: research