The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
The protective role of circ_0016760 downregulation against sevoflurane ‑induced neurological impairment via modulating miR‑145 expression in aged rats
This study focused on the effect of circ_0016760 on sevoflurane‑induced neurological impairment. The GEO database (GSE147277) and RT‑qPCR were used to predict and measure the circ_0016760 expression. The interaction of circ_0016760 and miR‑145 was verified by dual‑luciferase reporter assay. The CCK‑8 assay, flow cytometry, ELISA, ROS kit, MWM test were carried out to measure the cell viability, apoptosis, inflammation indicators, ROS level, and cognitive and memory function of the rats. Sevoflurane exacerbated neurotoxicity by restraining cell viability, inducing cell apoptosis, neuroinflammation, and ROS generat...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Peiyu Shuai Zhihong Hu Wei Li Guoliang You Zhiye Liu Niandong Zheng Source Type: research
