Inhibitory activity of aromatic plant extracts against dairy-related Clostridium species and their use to prevent the late blowing defect of cheese
Food Microbiol. 2023 Apr;110:104185. doi: 10.1016/j.fm.2022.104185. Epub 2022 Nov 7.ABSTRACTThe aim of the present work was the selection of aromatic plant essential oils (EOs) and/or ethanolic extracts (EEs) to prevent the late blowing defect (LBD) of cheese caused by Clostridium spp. EEs resulted more effective than EOs to inhibit dairy-borne Clostridium spp. in vitro. Savory, hyssop, lavender and tarragon EEs, which showed the lowest minimal inhibitory concentration against Clostridium tyrobutyricum, were selected to study the prevention of LBD caused by this bacterium in cheese. Addition of savory and lavender EEs to c...
Source: Food Microbiology - December 3, 2022 Category: Food Science Authors: Marta Ávila Javier Calzada Nuria Mu ñoz-Tébar Carmen S ánchez Gonzalo Ortiz de Elguea-Culebras Manuel Carmona Ana Molina M Isabel Berruga Sonia Garde Source Type: research

Inhibitory activity of aromatic plant extracts against dairy-related Clostridium species and their use to prevent the late blowing defect of cheese
Food Microbiol. 2023 Apr;110:104185. doi: 10.1016/j.fm.2022.104185. Epub 2022 Nov 7.ABSTRACTThe aim of the present work was the selection of aromatic plant essential oils (EOs) and/or ethanolic extracts (EEs) to prevent the late blowing defect (LBD) of cheese caused by Clostridium spp. EEs resulted more effective than EOs to inhibit dairy-borne Clostridium spp. in vitro. Savory, hyssop, lavender and tarragon EEs, which showed the lowest minimal inhibitory concentration against Clostridium tyrobutyricum, were selected to study the prevention of LBD caused by this bacterium in cheese. Addition of savory and lavender EEs to c...
Source: Food Microbiology - December 3, 2022 Category: Food Science Authors: Marta Ávila Javier Calzada Nuria Mu ñoz-Tébar Carmen S ánchez Gonzalo Ortiz de Elguea-Culebras Manuel Carmona Ana Molina M Isabel Berruga Sonia Garde Source Type: research

Molecules, Vol. 27, Pages 6427: Artemisia Species with High Biological Values as a Potential Source of Medicinal and Cosmetic Raw Materials
ka Szopa Artemisia species play a vital role in traditional and contemporary medicine. Among them, Artemisia abrotanum, Artemisia absinthium, Artemisia annua, Artemisia dracunculus, and Artemisia vulgaris are the most popular. The chemical composition and bioactivity of these species have been extensively studied. Studies on these species have confirmed their traditional applications and documented new pharmacological directions and their valuable and potential applications in cosmetology. Artemisia ssp. primarily contain sesquiterpenoid lactones, coumarins, flavonoids, and phenolic acids. Essential oils obtained from ...
Source: Molecules - September 29, 2022 Category: Chemistry Authors: Halina Ekiert Marta Klimek-Szczykutowicz Agnieszka Rzepiela Pawe ł Klin Agnieszka Szopa Tags: Review Source Type: research

Anticancer Properties of Kaempferol on Cellular Signaling Pathways
Curr Top Med Chem. 2022 Sep 7. doi: 10.2174/1568026622666220907112822. Online ahead of print.ABSTRACTPolyhydroxy compounds are secondary metabolites that are ubiquitous in plants of higher genera. They possess therapeutic properties against a wide spectrum of diseases, including cancers, neurodegenerative disorders, atherosclerosis, as well as cardiovascular disease. The phytochemical flavonol (a type of flavonoid) kaempferol (KMP) (3,5,7-trihydroxy-2-(4-hydroxyphenyl)- 4Hchromen-4-one) is abundant in cruciferous vegetables, including broccoli, kale, spinach, and watercress, as well as in herbs like dill, chives, and tarra...
Source: Current Topics in Medicinal Chemistry - September 9, 2022 Category: Chemistry Authors: Bidisha Sengupta Pragnya Biswas Debarshi Roy Justin Lovett Laken Simington Darrell R Fry Kaelin Travis Source Type: research

Anticancer Properties of Kaempferol on Cellular Signaling Pathways
Curr Top Med Chem. 2022 Sep 7. doi: 10.2174/1568026622666220907112822. Online ahead of print.ABSTRACTPolyhydroxy compounds are secondary metabolites that are ubiquitous in plants of higher genera. They possess therapeutic properties against a wide spectrum of diseases, including cancers, neurodegenerative disorders, atherosclerosis, as well as cardiovascular disease. The phytochemical flavonol (a type of flavonoid) kaempferol (KMP) (3,5,7-trihydroxy-2-(4-hydroxyphenyl)- 4Hchromen-4-one) is abundant in cruciferous vegetables, including broccoli, kale, spinach, and watercress, as well as in herbs like dill, chives, and tarra...
Source: Current Topics in Medicinal Chemistry - September 9, 2022 Category: Chemistry Authors: Bidisha Sengupta Pragnya Biswas Debarshi Roy Justin Lovett Laken Simington Darrell R Fry Kaelin Travis Source Type: research

Anticancer Properties of Kaempferol on Cellular Signaling Pathways
Curr Top Med Chem. 2022 Sep 7. doi: 10.2174/1568026622666220907112822. Online ahead of print.ABSTRACTPolyhydroxy compounds are secondary metabolites that are ubiquitous in plants of higher genera. They possess therapeutic properties against a wide spectrum of diseases, including cancers, neurodegenerative disorders, atherosclerosis, as well as cardiovascular disease. The phytochemical flavonol (a type of flavonoid) kaempferol (KMP) (3,5,7-trihydroxy-2-(4-hydroxyphenyl)- 4Hchromen-4-one) is abundant in cruciferous vegetables, including broccoli, kale, spinach, and watercress, as well as in herbs like dill, chives, and tarra...
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Bidisha Sengupta Pragnya Biswas Debarshi Roy Justin Lovett Laken Simington Darrell R Fry Kaelin Travis Source Type: research

Anticancer Properties of Kaempferol on Cellular Signaling Pathways
Curr Top Med Chem. 2022 Sep 7. doi: 10.2174/1568026622666220907112822. Online ahead of print.ABSTRACTPolyhydroxy compounds are secondary metabolites that are ubiquitous in plants of higher genera. They possess therapeutic properties against a wide spectrum of diseases, including cancers, neurodegenerative disorders, atherosclerosis, as well as cardiovascular disease. The phytochemical flavonol (a type of flavonoid) kaempferol (KMP) (3,5,7-trihydroxy-2-(4-hydroxyphenyl)- 4Hchromen-4-one) is abundant in cruciferous vegetables, including broccoli, kale, spinach, and watercress, as well as in herbs like dill, chives, and tarra...
Source: Current Topics in Medicinal Chemistry - September 9, 2022 Category: Chemistry Authors: Bidisha Sengupta Pragnya Biswas Debarshi Roy Justin Lovett Laken Simington Darrell R Fry Kaelin Travis Source Type: research

Nanoemulsion and nanogel containing Artemisia dracunculus essential oil; larvicidal effect and antibacterial activity
Microbial infections and mosquito-borne diseases such as malaria, with 627 k deaths in 2020, are still major public health challenges. (Source: BMC Research Notes)
Source: BMC Research Notes - August 12, 2022 Category: Research Authors: Mahmoud Osanloo, Samira Firooziyan, Abbas Abdollahi, Shekoufeh Hatami, Amene Nematollahi, Narges Elahi and Elham Zarenezhad Tags: Research note Source Type: research

Ethanolic Extract of Artemisia dracunculus L. Enhances the Metabolic Benefits of Exercise in Diet-induced Obese Mice—Corrigendum
No abstract available (Source: Medicine and Science in Sports and Exercise)
Source: Medicine and Science in Sports and Exercise - November 15, 2021 Category: Sports Medicine Tags: SPECIAL COMMUNICATIONS: Corrigendum Source Type: research

Molecules, Vol. 26, Pages 6678: Antimicrobial Effects of Basil, Summer Savory and Tarragon Lyophilized Extracts in Cold Storage Sausages
Daniela Cojocari The problem of functional foods with bioactive components of natural origin is current for the food industry. Plant extracts rich in polyphenols with antioxidant and antimicrobial activity are a promising source for use in improving the quality and characteristics of fresh meat and meat products. In this context, the purpose of the present study was to evaluate the physico-chemical, microbiological, sensory properties of sausages prepared with the addition of lyophilized extract of basil, thyme or tarragon. For the beginning, the total amount of polyphenols, the antioxidant and antimicrobial activity o...
Source: Molecules - November 4, 2021 Category: Chemistry Authors: Artur Macari Rodica Sturza Ildiko Lung Maria-Loredana Soran Ocsana Opri ş Greta Balan Aliona Ghendov-Mosanu Dan Cristian Vodnar Daniela Cojocari Tags: Article Source Type: research

Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that PMI-5011 increases Thr172-phosphorylation of AMPK in muscle cells and skeletal muscle tissue, while hepatic AMPK activation by PMI-5011 was not observed. Increased AMPK activity by PMI-5011 affects downstream signaling of AMPK, resulting in inhibition of ACC and increased SIRT1 protein levels. Selective deletion of DMC-2 from PMI-5011 demonstrates that compounds other than DMC-2 in a "DMC-2 knock out extract" (KOE) are responsible for AMPK activation and its downstream effects. Com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2021 Category: Drugs & Pharmacology Authors: B Vandanmagsar Y Yu C Simmler T N Dang P Kuhn A Poulev D M Ribnicky G F Pauli Z E Floyd Source Type: research

Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that PMI-5011 increases Thr172-phosphorylation of AMPK in muscle cells and skeletal muscle tissue, while hepatic AMPK activation by PMI-5011 was not observed. Increased AMPK activity by PMI-5011 affects downstream signaling of AMPK, resulting in inhibition of ACC and increased SIRT1 protein levels. Selective deletion of DMC-2 from PMI-5011 demonstrates that compounds other than DMC-2 in a "DMC-2 knock out extract" (KOE) are responsible for AMPK activation and its downstream effects. Com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2021 Category: Drugs & Pharmacology Authors: B Vandanmagsar Y Yu C Simmler T N Dang P Kuhn A Poulev D M Ribnicky G F Pauli Z E Floyd Source Type: research

Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that PMI-5011 increases Thr172-phosphorylation of AMPK in muscle cells and skeletal muscle tissue, while hepatic AMPK activation by PMI-5011 was not observed. Increased AMPK activity by PMI-5011 affects downstream signaling of AMPK, resulting in inhibition of ACC and increased SIRT1 protein levels. Selective deletion of DMC-2 from PMI-5011 demonstrates that compounds other than DMC-2 in a "DMC-2 knock out extract" (KOE) are responsible for AMPK activation and its downstream effects. Com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2021 Category: Drugs & Pharmacology Authors: B Vandanmagsar Y Yu C Simmler T N Dang P Kuhn A Poulev D M Ribnicky G F Pauli Z E Floyd Source Type: research

Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that PMI-5011 increases Thr172-phosphorylation of AMPK in muscle cells and skeletal muscle tissue, while hepatic AMPK activation by PMI-5011 was not observed. Increased AMPK activity by PMI-5011 affects downstream signaling of AMPK, resulting in inhibition of ACC and increased SIRT1 protein levels. Selective deletion of DMC-2 from PMI-5011 demonstrates that compounds other than DMC-2 in a "DMC-2 knock out extract" (KOE) are responsible for AMPK activation and its downstream effects. Com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2021 Category: Drugs & Pharmacology Authors: B Vandanmagsar Y Yu C Simmler T N Dang P Kuhn A Poulev D M Ribnicky G F Pauli Z E Floyd Source Type: research

Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
This study examined PMI-5011 activation of AMPK signaling using murine C2C12 muscle cell culture and skeletal muscle tissue. Findings show that PMI-5011 increases Thr172-phosphorylation of AMPK in muscle cells and skeletal muscle tissue, while hepatic AMPK activation by PMI-5011 was not observed. Increased AMPK activity by PMI-5011 affects downstream signaling of AMPK, resulting in inhibition of ACC and increased SIRT1 protein levels. Selective deletion of DMC-2 from PMI-5011 demonstrates that compounds other than DMC-2 in a "DMC-2 knock out extract" (KOE) are responsible for AMPK activation and its downstream effects. Com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2021 Category: Drugs & Pharmacology Authors: B Vandanmagsar Y Yu C Simmler T N Dang P Kuhn A Poulev D M Ribnicky G F Pauli Z E Floyd Source Type: research