Immunomodulation Induced in BALB/c Mice after Subacute Exposure to Hydroalcoholic Extract of Artimisia Dracunculus
CONCLUSION: Based on our findings, HET has potent immunostimulant characteristics. More investigation into tarragon's potential to be used in the treatment of disorders caused by a weakened immune response should be conducted.PMID:38279720 | DOI:10.2174/0115701638279953231222062644 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - January 27, 2024 Category: Drugs & Pharmacology Authors: Fatemeh Forouzanfar Mostafa Moshirian-Farahi Hassan Rakhshande Bahram Memar Roghayeh Rashidi Ramin Mahdipour Bamdad Riahi-Zanjani Source Type: research
Infection-Related Glomerulonephritis in Children and Adults
Infection-related glomerulonephritis is an immunologically mediated glomerular injury after an infection. Glomerulonephritis may occur with the infection or after a variable latent period. Poststreptococcal glomerulonephritis (PSGN) is the prototype of infection-related glomerulonephritis. The streptococcal antigens, nephritis-associated plasmin-like receptor and streptococcal exotoxin B, have emerged as major players in the pathogenesis of PSGN. Although PSGN is the most common infection-related glomerulonephritis in children, in adults, glomerulonephritis is secondary to bacteria such as staphylococci, viruses such as he...
Source: Seminars in Nephrology - January 19, 2024 Category: Urology & Nephrology Authors: Arpana Iyengar, Nivedita Kamath, Jai Radhakrishnan, Blanca Tarragon Estebanez Source Type: research
Extraction of Functional Compounds from Tarragon (Artemisia dracunculus L.) by Deep Eutectic Solvents at Different Properties
In this study, it was aimed to examine the capacity of deep eutectic solvents (DESs) with different contents to extract bioactive compounds from tarragon (Artemisia dracunculus L.) plant. For this reason, the total phenolic-flavonoid substance, total proanthocyanidin content and antioxidant/antimicrobial activities of the prepared DES extracts were investigated, as well as the individual phenolic contents and individual amino acid contents. According to the results, DES10 had the highest efficiency in terms of its capacity to extract individual phenolics (approximately 59 mg/100g) and individual amino acids (approximately ...
Source: Chemistry and Biodiversity - August 13, 2023 Category: Biochemistry Authors: Yusuf Can Ger çek Naciye Kutlu Saffet Çelik Bet ül Gıdık Sinan Bayram Nesrin Ecem Bayram Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
A novel mutation in the NNT gene causing familial glucocorticoid deficiency, with a literature review
We report the case of a 3-year-old boy recently diagnosed with FGD type 4 due to a novel mutation in NNT gene. A homozygous variant in exon 18 of the NNT gene, NM_012343.3:c.2764C>T, p.(Arg922*), determines a stop codon and, consequently, a non-functional truncated protein or absence of protein due to the nonsense-mediated decay (NMD) mechanism. We review the recent literature on NNT mutations and clinical presentations, which are broader than suspected. This disorder can result in significant morbidity and is potentially fatal if untreated. Precise diagnosis allows correct treatment and follow up.PMID:37352919 | DOI:10...
Source: Annales d'Endocrinologie - June 23, 2023 Category: Endocrinology Authors: Natividad Pons Ana Moriano Bel én Taberner Andr és Tarragon Eva D íez Ÿngel Zuñiga Cabrera Source Type: research
