603 Differences in dosing strategies and perinatal outcomes for pregnant persons on buprenorphine compared with buprenorphine-naloxone
This study sought to compare perinatal outcomes between buprenorphine (BUP) and BUP-NA along with evaluating dosing alterations in pregnancy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2024 Category: OBGYN Authors: Emily H. Stetler, Tiffany Yang, Oladunni Ogundipe, Lauren Stewart, Chaitali Korgaonkar-Cherala, Julia Kim, Rakasa Pattanaik, Erika Zambrano Alvarez, Kimberly Herrera, Diana Garretto, David Garry, Cassandra Heiselman Source Type: research

Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario
We examined the impact of the release of the OUD management guideline on OAT initiation rates using Autoregressive Integrated Moving Average models.RESULTS: Among 20 702 hospital visits for opioid toxicity among patients with OUD, the median age was 35 years, and 65.1% were male. Over the study period, the percentage of visits leading to OAT initiation within 7 days rose from 1.7% or less (Q1 2013) to 5.6% (Q1 2020); however, the publication of the Canadian OUD management guideline was not associated with a significant increase in these rates (0.14% slope change, 95% confidence interval -0.11% to 0.38%; p = 0.3).INTERPRETA...
Source: cmaj - December 18, 2023 Category: General Medicine Authors: Tina Hu Daniel McCormack David N Juurlink Tonya J Campbell Ahmed M Bayoumi Pamela Leece Jessica T Kent Tara Gomes Source Type: research

Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario
We examined the impact of the release of the OUD management guideline on OAT initiation rates using Autoregressive Integrated Moving Average models.RESULTS: Among 20 702 hospital visits for opioid toxicity among patients with OUD, the median age was 35 years, and 65.1% were male. Over the study period, the percentage of visits leading to OAT initiation within 7 days rose from 1.7% or less (Q1 2013) to 5.6% (Q1 2020); however, the publication of the Canadian OUD management guideline was not associated with a significant increase in these rates (0.14% slope change, 95% confidence interval -0.11% to 0.38%; p = 0.3).INTERPRETA...
Source: Canadian Medical Association Journal - December 18, 2023 Category: General Medicine Authors: Tina Hu Daniel McCormack David N Juurlink Tonya J Campbell Ahmed M Bayoumi Pamela Leece Jessica T Kent Tara Gomes Source Type: research

Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario
We examined the impact of the release of the OUD management guideline on OAT initiation rates using Autoregressive Integrated Moving Average models.RESULTS: Among 20 702 hospital visits for opioid toxicity among patients with OUD, the median age was 35 years, and 65.1% were male. Over the study period, the percentage of visits leading to OAT initiation within 7 days rose from 1.7% or less (Q1 2013) to 5.6% (Q1 2020); however, the publication of the Canadian OUD management guideline was not associated with a significant increase in these rates (0.14% slope change, 95% confidence interval -0.11% to 0.38%; p = 0.3).INTERPRETA...
Source: cmaj - December 18, 2023 Category: General Medicine Authors: Tina Hu Daniel McCormack David N Juurlink Tonya J Campbell Ahmed M Bayoumi Pamela Leece Jessica T Kent Tara Gomes Source Type: research