HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)
Funding Opportunity RFA-NS-24-018 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery of strong candidate biomarkers or biomarker signatures for pain that can be used to facilitate the testing of non-opioid pain therapeutics in Phase II clinical trials.The biomarkers or biomarker signature will be developed through clinical research specifically focused on the identification of pain biomarkers or biosignatures that predict and/or monitor response to pain therapeutics. The resulting biomarkers or biomarker signatures may be focused on a singl...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 15, 2023 Category: Research Source Type: funding
Take Advantage of Our Many Resources for Enhancing the Rigor of Animal Research
“Despite the numerous successes stemming from animal research, concerning reports over the past decade have described biomedical experiments that fail to replicate or to translate in ways that improve human health. All research is not expected to translate to human treatments, as there is no perfect model. Scientific process is as much about failure as it is about success. Yet part of the scientific process is also continual improvement, which includes working to understand what might contribute to unexpected outcomes within animal research.”
The Advisory Committee to the NIH Director (ACD) expressed that view in their...
Source: NIH Extramural Nexus - February 10, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Alternatives to Animals reproducibility rigor Source Type: funding
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Funding Opportunity PAR-23-090 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2023 Category: Research Source Type: funding
Conference for Early Stage HIV/AIDS Researchers Using Nonhuman Primate Models (R13 Clinical Trial Not Allowed)
The objectives of the meeting(s) supported by this FOA are to provide these early stage HIV/AIDS researchers with guidance on conducting preclinical research to inform clinical trials on reducing the incidence of HIV/AIDS infection, including vaccine development and testing; developing next-generation HIV therapies, including potential cure therapies; treatment of HIV-associated coinfections, comorbidities and complications; and infection prevention strategies. In addition to guidance on translating results to clinical trials, the conference should target developing skills related to networking, grantsmanship, and goal/mil...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2023 Category: Research Source Type: funding
Notice of Special Interest (NOSI): Computational and Statistical Methods to Enhance Discovery from Health Data
Notice NOT-LM-23-001 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 19, 2023 Category: Research Source Type: funding
Algorithms for Threat Detection (ATD)
Full Proposal Deadline Date: February 15, 2023 Program Guidelines: NSF 20-531The Algorithms for Threat Detection (ATD) program will support research projects to develop the next generation of mathematical and statistical algorithms for analysis of large spatiotemporal datasets with application to quantitative models of human dynamics. The program is a partnership between the Division of Mathematical Sciences (DMS) at the National Science Foundation (NSF) and the National Geospatial Intelligence Agency (NGA).More at https://beta.nsf.gov/programid/503427This is an NSF Upcoming Due Dates item. (Source: NSF Upcoming Due Dates)
Source: NSF Upcoming Due Dates - January 16, 2023 Category: Science Source Type: funding
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Funding Opportunity PAR-23-096 from the NIH Guide for Grants and Contracts. NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and quality of digital mental health interventions. This FOA is intended to support the development of digital health test beds that leverage well-established digital mental health platforms,to rapidly refine and optimize existing evidence-based digital health interventions and conduct clinical trials testing digital mental health interventions that are statistically powered to provide a definitive answer regarding the in...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2023 Category: Research Source Type: funding
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-088 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the pace of translation of NCI-supported methods/assays/technologies (referred to as "assays") to the clinic. Specifically, the focus of this FOA is on the adaption and clinical validation of molecular/cellular/imaging markers (referred to as "markers" r "biomarkers") for cancer detection, diagnosis, prognosis, monitoring, and prediction of response in treatment, as well as markers for cancer control and prevention. Research applications may support the acquisition of we...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2023 Category: Research Source Type: funding
Research on the Science and Technology Enterprise: Indicators, Statistics, and Methods (NCSES S & T)
Full Proposal Deadline Date: January 17, 2023 Program Guidelines: NSF 21-627The National Center for Science and Engineering Statistics (NCSES) of the National Science Foundation (NSF) is one of the thirteen principal federal statistical agencies within the United States. It is responsible for the collection, acquisition, analysis, reporting and dissemination of objective, statistical data related to the science and technology (S&T) enterprise in the United States and other nations that is relevant and useful to practitioners, researchers, policymakers and ...More at https://beta.nsf.gov/programid/5265This is an N...
Source: NSF Upcoming Due Dates - December 18, 2022 Category: Science Source Type: funding
Pre-Application Webinars for NCI Cancer Screening Research Network (CSRN): ACCrual, Enrollment, and Screening Sites Hub (RFA-CA-23-020); Statistics and Data Management Center (RFA-CA-23-021); and Coordinating and Communication Center (RFA-CA-23-022)
Notice NOT-CA-23-017 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 23, 2022 Category: Research Source Type: funding
NCI Cancer Screening Research Network: Statistics and Data Management Center (UG1 Clinical Trial Required)
Funding Opportunity RFA-CA-23-021 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is one of three FOAs that will support a comprehensive effort by the National Cancer Institute (NCI) to provide infrastructure to develop and conduct national cancer screening clinical trials and studies through the Cancer Screening Research Network (CSRN). The primary goal of the CSRN is the conduct of multi-center cancer screening trials and studies. This Network is designed to take advantage of large and diverse populations receiving routine care in a variety of healthcare settings. The CSRN will...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 17, 2022 Category: Research Source Type: funding
Statistics
Full Proposal Window: December 15, 2022 Program Guidelines: PD 18-1269The Statistics Program supports research in statistical theory and methods, including research in statistical methods for applications to any domain of science and engineering. The theory forms the base for statistical science. The methods are used for stochastic modeling, and the collection, analysis and interpretation of data. The methods characterize uncertainty in the data and facilitate advancement in science and engineering. The Program encourages proposals ranging from ...More at https://beta.nsf.gov/programid/5556This is an NSF Upcoming Due Dates...
Source: NSF Upcoming Due Dates - November 15, 2022 Category: Science Source Type: funding
Follow-Up Career Stage Analyses of Applications Submitted During the Pandemic (Part 6)
Our series of blog posts on the distributions of gender and race of designated principal investigators (PIs) of R01 and RPG applications submitted before and after the onset of the COVID-19 pandemic continues today. When looking back, posts from April 2022, October 2021, June 2021, and July 2020 did not show any particularly marked differences in the high-level demographics of designated PIs during the course of the pandemic.
In response to reader comments, we looked at applications broken down by career stage in June 2022. It was interesting to notice slowly increasing trends in the proportions of early stage investigat...
Source: NIH Extramural Nexus - October 13, 2022 Category: Research Authors: Mike Lauer Tags: blog Open Mike applications COVID-19 Funding data Source Type: funding
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH)
Full Proposal Deadline Date: November 10, 2022 Program Guidelines: NSF 21-530The purpose of this interagency program solicitation is to support the development of transformative high-risk, high-reward advances in computer and information science, engineering, mathematics, statistics, behavioral and/or cognitive research to address pressing questions in the biomedical and public health communities. Transformations hinge on scientific and engineering innovations by interdisciplinary teams that develop novel methods to intuitively and intelligently collect, ...More at https://beta.nsf.gov/programid/504739This is an ...
Source: NSF Upcoming Due Dates - October 11, 2022 Category: Science Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for NCI Cancer Screening Research Network: Statistics and Data Management Center (UG1 Clinical Trial Required)
Notice NOT-CA-22-130 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 28, 2022 Category: Research Source Type: funding
