Animal Welfare Webinar: Foundations for Evaluating Study Design and Statistical Approaches for the IACUC
Do you want more tools to understand good experimental design when reviewing animal use protocols? Watch this informative webinar hosted by the NIH Office of Laboratory Animal Welfare on approaches for the Institutional Animal Care and Use Committee (IACUC) to effectively evaluate study design, animal numbers, and statistical descriptions in animal protocols. By focusing on concepts rather than mathematical equations, this webinar is for all IACUC members regardless of scientific or statistical background.   (Source: NIH Extramural Nexus)
Source: NIH Extramural Nexus - April 28, 2023 Category: Research Authors: NIH Staff Tags: New Resources Animal Welfare Source Type: funding

How Many Researchers: The FY 2022 Cumulative Investigator Rate  
We are pleased to share our annual snapshot of how many researchers NIH supports. These fiscal year (FY) 2022 data are also available in the NIH Data Book (see report #303) and represent awards made with traditional and supplemental coronavirus appropriations. Please keep in mind that these data are distinct from success rates, however, which are application-based metrics (see this post). Our cumulative investigator rate is an NIH-wide person-based metric. The metric is calculated as the number of unique principal investigators who were designated on an NIH research project grant (RPG), activity or mechanism, divided by...
Source: NIH Extramural Nexus - April 18, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike cumulative investigator rate Funding data funding rate Source Type: funding

Data Integration and Statistical Analysis Methods (DISAM) (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HG-23-005 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) solicits applications to develop innovative and generalizable statistical methods to enable analysis of data from the human Developmental Genotype-Expression (dGTEx) and non-human primate (NHP dGTEx) projects. Methods that assess the influence of genetic variation on development, compare gene expression and regulation across tissues and time points, or leverage comparative genomics to understand developmental and evolutionary processes and integrate with existing tissue and cell atlas efforts are stro...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 18, 2023 Category: Research Source Type: funding

Dear Colleague Letter: Interdisciplinary REU Sites at the Intersection of Computing and Communication Foundations and Mathematics and Statistics
Available Formats: HTML: https://www.nsf.gov/pubs/2023/nsf23082/nsf23082.jsp?WT.mc_id=USNSF_25&WT.mc_ev=clickPDF: https://www.nsf.gov/pubs/2023/nsf23082/nsf23082.pdf?WT.mc_id=USNSF_25&WT.mc_ev=clickDocument Number: nsf23082This is an NSF Program Announcements and Information item. (Source: NSF Program Announcements and Information)
Source: NSF Program Announcements and Information - April 5, 2023 Category: Science Source Type: funding

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
Funding Opportunity RFA-DC-24-001 from the NIH Guide for Grants and Contracts. Invasive surgical procedures offer the opportunity for unique intracranial interventions such as the ability to record and stimulate intracranially within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and need to be aggregated in a manner that addresses research questions with appropriate statistical power. Therefore, this RFA seeks applications to assemble diverse, integrated, mul...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 3, 2023 Category: Research Source Type: funding

Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)
Funding Opportunity PAR-22-265 from the NIH Guide for Grants and Contracts. Reissue of PAR-17-096. The Jointly Sponsored NIH Predoctoral Training Program in the Neurosciences (JSPTPN) is an institutional program that supports broad and fundamental research training in the neurosciences. In addition to a broad education in the neurosciences, a key component will be a curriculum that provides a strong foundation in experimental design, statistical methodology and quantitative reasoning. JSPTPN programs are intended to be 2 years in duration and students may only be appointed to this training grant during the first 2 years...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2023 Category: Research Source Type: funding

NINDS Institutional AD/ADRD Research Training Program (T32 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-113 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for institutional research training programs in Alzheimers Disease/Alzheimers Disease-Related Dementias (AD/ADRD). These institutional research training programs should produce well-trained neuroscientists who leave the program with the research skills and scientific knowledge to make a significant contribution to research on AD/ADRD cognitive impairment and dementia. Programs should be designed to enhance the breadth and depth of training across the spectrum AD/ADRD research areas (e.g. AD, Vascular...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2023 Category: Research Source Type: funding

Mentored Career Development Application (K) Funding Rates by Race-Ethnicity FY 2010-FY 2022
Marie A. Bernard, M.D., Chief Officer forScientific Workforce Diversity In this post, we analyze funding rates for Fiscal Year (FY) 2010 to FY 2022 mentored career development award (K) applicants according to the race-ethnicity of designated Principal Investigators (PIs). Receipt of a career development award often presages R01 receipt. We used data from frozen, official, NIH success rate files. We focus on applicants for K01, K08, K23, K25,and K99 direct budget authority awards. We obtained data on the race and ethnicity of PIs from their entries into the eRA Commons Personal Profile. As noted by NIH, PIs provide these d...
Source: NIH Extramural Nexus - March 16, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Diversity Funding data scientific workforce diversity Source Type: funding

Analyses of Demographic-Specific Funding Rates for Type 1 Research Project Grant and R01-Equivalent Applications
Marie A. Bernard, M.D., Chief Officer forScientific Workforce Diversity In this post, we analyze funding rates for Fiscal Year (FY) 2010 to FY 2022 Type 1 Research Project Grant (RPG) and Type 1 R01-Equivalent applicants according to the race-ethnicity of designated Principal Investigators (PIs). We used data from frozen, official, NIH success rate files. We obtained data on the race and ethnicity of PIs from their entries into the eRA Commons Personal Profile. As noted by NIH, PIs provide these data on a strictly voluntary basis, and these data are not used for making funding decisions. If individuals described themselves...
Source: NIH Extramural Nexus - March 16, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Diversity Funding data scientific workforce diversity Source Type: funding

BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-24-004 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-020: Understanding the dynamic activity of brain circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). This FOA seeks exceptionally creative approach...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding

BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-24-005 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding

FY 2022 By the Numbers: Extramural Grant Investments in Research
Today we present our annual snapshot of NIH grant funding and success rate data for fiscal year (FY) 2022 enacted appropriations. These data are available in the NIH Data Book, which is also being regularly updated with other FY 2022 grants information. Similar to our FY 2021 and FY 2020 posts, spending related to special appropriations for coronavirus are excluded here, but may be found using RePORTER’s advanced search capabilities. In FY2022, NIH spent $33.3 billion of its total $45.2 billion appropriation for competing and noncompeting grant awards. This is a 3.1% increase (or $1.02 billion) in spending over the p...
Source: NIH Extramural Nexus - March 1, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike awards grants Success Rate Source Type: funding

Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-23-275 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage research to integrate/harmonize existing large prevention trial data sets implemented earlier in life to examine whether they reduce risk for later suicide, including suicide thoughts and behaviorsfatal and nonfatal (STB), and related external injuries (e.g., nonfatal SUD/OUD/accidents, and all-cause mortality (e.g., National Death Index). This U01 will be competed and funded to: 1) obtain existing prevention trial data sets, with collaboration of the PIs who have the ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 27, 2023 Category: Research Source Type: funding

Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R01 Clinical Trials Not Allowed)
Funding Opportunity RFA-DA-24-008 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to attract data and computational scientists to propose novel ways to integrate data of different types and scales to allow new types of analysis. It is expected that with the development and application of novel computational, bioinformatics, statistical, and analytical approaches, previously inaccessible insights will reveal new aspects of addiction biology. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2023 Category: Research Source Type: funding

Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R21 Clinical Trials Not Allowed)
Funding Opportunity RFA-DA-24-009 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to attract data and computational scientists to propose novel ways to integrate data of different types and scales to allow new types of analysis. It is expected that with the development and application of novel computational, bioinformatics, statistical, and analytical approaches, previously inaccessible insights will reveal new aspects of addiction biology. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2023 Category: Research Source Type: funding