Janssen Announces New Data Supporting Safety and Efficacy of RYBREVANT ® and Lazertinib Combination for Patients with Non-Small Cell Lung Cancer and EGFR Mutations
July 26, 2022 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 1b/2 CHRYSALIS-2 study (NCT04077463) cohort evaluating the safety and tolerability of the combination of RYBREVANT® (amivantamab-vmjw) with the third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) lazertinib and platinum-based chemotherapy (carboplatin and pemetrexed) in patients with relapsed/refractory non-small cell lung cancer (NSCLC) and EGFR mutations.[1] These findings and additional updates, including data on RYBREVANT® in combination with laze...
Source: Johnson and Johnson - July 26, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

Sodium Acetate (Sodium Acetate Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 26, 2022 Category: Drugs & Pharmacology Source Type: news

People With Diabetes Are More Vulnerable to Heart Disease. How to Reduce the Risk
If you’ve been diagnosed with diabetes, know that you’ve got plenty of company. The American Diabetes Association (ADA) reports that in 2019, the most recent year for which data is available, 37.3 million adults in the U.S.—about 11.3% of the population—had the chronic condition, and that number continues to grow. Type 1 diabetes develops when the body isn’t able to produce insulin, and Type 2 occurs when the body doesn’t use insulin correctly. Type 2 is the most common form of diabetes, and when it’s uncontrolled, a person’s blood sugar can jump to dangerous levels that requ...
Source: TIME: Health - July 20, 2022 Category: Consumer Health News Authors: Elaine K. Howley Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news

Sodium Lactate (Sodium Lactate Injection in AVIVA) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 20, 2022 Category: Drugs & Pharmacology Source Type: news

Avadel Pharmaceuticals Announces Tentative Approval of Lumryz (sodium oxybate) Extended-Release Oral Suspension
Validates the safety profile and clinical efficacy of Lumryz Pursuing strategies to accelerate final approval DUBLIN, Ireland, July 19, 2022 (GLOBE NEWSWIRE) -- Avadel Pharmaceuticals plc (Nasdaq: AVDL), a biopharmaceutical company focused on... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - July 19, 2022 Category: Drugs & Pharmacology Source Type: news

Overly Tight Sodium Restriction May Worsen HFpEF Outcomes Overly Tight Sodium Restriction May Worsen HFpEF Outcomes
Results of a new TOPCAT analysis point to the need to determine the optimal salt restriction range for patients with heart failure with preserved ejection fraction.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 19, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

Life-threatening pediatric poisoning due to ingestion of Bufo bufo toad eggs: a case report - Gambassi F, Lanzi C, Ricci Z, Duchini P, L'Erario M, Mannaioni G, Cini N, Bonari A, Saffirio C, Occupati B.
Bufo parotid glands and eggs contain cardiac glycosides also known as bufadienolides. This class of molecules can cause digoxin-like cardiac toxicity, as they can block the sodium potassium-adenosine triphosphatase (Na/K-ATPase) pump. Poisoning with these ... (Source: SafetyLit)
Source: SafetyLit - July 18, 2022 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Suicide attempt using sodium nitrite ordered on the internet: two case reports - Yoon JC, Kim SE.
RATIONALE: Sodium nitrite is a potent oxidizing agent that impairs oxygen transport and delivery through methemoglobin formation. Clinical manifestations are known to induce methemoglobinemia, dysrhythmia, hypotension, and even death. While accidental into... (Source: SafetyLit)
Source: SafetyLit - July 18, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

These New Developments Could Make Living With Type 2 Diabetes More Manageable
Experts often talk about the “burden” of a disease or illness. The word acts as a tidy container for all the unpleasantness people with that condition may experience—from their symptoms, to the cost of their care, to the restrictions imposed on their lifestyle, to the health complications that may arise. For people with Type 2 diabetes, this burden can be high. Routine management of Type 2 diabetes often involves major changes to one’s diet and physical activity. And for many, especially those taking insulin to manage their blood sugar, the disease can necessitate daily blood-glucose monitoring, a p...
Source: TIME: Health - July 15, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news

Pheburane (Sodium Phenylbutyrate Oral Pellets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 14, 2022 Category: Drugs & Pharmacology Source Type: news

Efficacy and Safety of Diclofenac Patches for Cancer Pain Efficacy and Safety of Diclofenac Patches for Cancer Pain
Newly developed diclofenac sodium patches may provide a safe and effective option for the treatment of cancer pain.Pain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 14, 2022 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

How Heat Waves Could Have Long-Term Impacts on Your Health
Health officials from the U.S., the U.K., Europe, and Japan have been warning residents to stay out of the sun as the northern hemisphere experiences some of the highest early summer temperatures ever recorded. It’s not just to prevent heat-stroke, but to prevent the long-term consequences as well. As climate change drives summer temperatures even higher than usual, medical researchers are starting to find links between sustained heat exposure and chronic health conditions ranging from diabetes to kidney stones, cardiovascular disease and even obesity. “While increased risk for heat stroke is an obvious manifes...
Source: TIME: Health - July 13, 2022 Category: Consumer Health News Authors: Aryn Baker Tags: Uncategorized climate change Climate Is Everything Evergreen healthscienceclimate Londontime overnight Source Type: news

Pheburane (Sodium Phenylbutyrate Oral Pellets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 13, 2022 Category: Drugs & Pharmacology Source Type: news

FDA Approves Bludigo (indigotindisulfonate sodium) for Cystoscopic Assessment of the Ureters Following Urological and Gynecological Surgical Procedures
Marseille, France and Collegeville, PA, USA– July 12, 2022– Provepharm, a French company specialized in the development of pharmaceutical applications, today announces that it has received FDA New Drug Approval for the marketing of... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 12, 2022 Category: Drugs & Pharmacology Source Type: news

Webb telescope wows with first images
At long last, eager astronomers—and the public—get to view snapshots of the universe provided by the James Webb Space Telescope, the largest, most complex, and most expensive space telescope ever built. Yesterday, in a sneak preview , the White House released one picture, a deep image bristling with thousands of distant galaxies. Today, NASA released four more that demonstrate Webb’s ability to scrutinize gas clouds and planetary systems closer to home. The images—a product of Webb’s giant, majestic, gold-plated mirror—are not only sharper than those of the Hubble Space Telescope, but ...
Source: ScienceNOW - July 12, 2022 Category: Science Source Type: news