Sinonasal Burkitt Lymphoma in a 2-Year-Old Child: An Uncommon Case Report
We present the case of a 2-year-old boy who presented with a 2-month history of nasal obstruction, snoring, and epistaxis followed by a recent dyspnea. Examination revealed a protruding tissue mass in the left nasal cavity. Computed tomography scan showed a homogenous soft-tissue mass in the left nasal cavity extending toward the ipsilateral orbit, infratemporal fossa, nasopharynx, as well as the ethmoid and maxillary sinuses. Magnetic resonance imaging revealed a homogenous infiltrating mass with a hypo-intense signal on T2-weighted images reaching the infratemporal fossa and oropharynx. Biopsy confirmed the diagnosis of ...
Source: Ear, Nose and Throat Journal - November 7, 2023 Category: ENT & OMF Authors: Souha Kallel Sirine Ayedi Mariam Ben Ayed Noura Salem Imen Achour Khaireddine Ben Mahfoudh Mohamed Amin Chaabouni Ilhem Charfeddine Source Type: research
Long non-coding RNA FKSG29 regulates oxidative stress and endothelial dysfunction in obstructive sleep apnea
Mol Cell Biochem. 2023 Nov 2. doi: 10.1007/s11010-023-04880-3. Online ahead of print.ABSTRACTAltered expressions of pro-/anti-oxidant genes are known to regulate the pathophysiology of obstructive sleep apnea (OSA).We aim to explore the role of a novel long non-coding (lnc) RNA FKSG29 in the development of intermittent hypoxia with re-oxygenation (IHR)-induced endothelial dysfunction in OSA. Gene expression levels of key pro-/anti-oxidant genes, vasoactive genes, and the FKSG29 were measured in peripheral blood mononuclear cells from 12 subjects with primary snoring (PS) and 36 OSA patients. Human monocytic THP-1 cells and...
Source: Molecular and Cellular Biochemistry - November 2, 2023 Category: Biochemistry Authors: Yung-Che Chen Po-Yuan Hsu Mao-Chang Su Yung-Lung Chen Ya-Ting Chang Chien-Hung Chin I-Chun Lin Yu-Mu Chen Ting-Ya Wang Yong-Yong Lin Chiu-Ping Lee Meng-Chih Lin Chang-Chun Hsiao Source Type: research
Long non-coding RNA FKSG29 regulates oxidative stress and endothelial dysfunction in obstructive sleep apnea
Mol Cell Biochem. 2023 Nov 2. doi: 10.1007/s11010-023-04880-3. Online ahead of print.ABSTRACTAltered expressions of pro-/anti-oxidant genes are known to regulate the pathophysiology of obstructive sleep apnea (OSA).We aim to explore the role of a novel long non-coding (lnc) RNA FKSG29 in the development of intermittent hypoxia with re-oxygenation (IHR)-induced endothelial dysfunction in OSA. Gene expression levels of key pro-/anti-oxidant genes, vasoactive genes, and the FKSG29 were measured in peripheral blood mononuclear cells from 12 subjects with primary snoring (PS) and 36 OSA patients. Human monocytic THP-1 cells and...
Source: Molecular and Cellular Biochemistry - November 2, 2023 Category: Biochemistry Authors: Yung-Che Chen Po-Yuan Hsu Mao-Chang Su Yung-Lung Chen Ya-Ting Chang Chien-Hung Chin I-Chun Lin Yu-Mu Chen Ting-Ya Wang Yong-Yong Lin Chiu-Ping Lee Meng-Chih Lin Chang-Chun Hsiao Source Type: research
Obstructive Sleep Apnea Hypopnea Syndrome & Glaucoma
This study suggests that the OSAHS may be an aggravating factor for glaucoma. The OSAHS –POAG association recommends IOP monitoring during CPAP therapy.Targeted and optimized screening OSAHS in glaucomatous patients will undoubtedly contribute to adequate management of this progressive optic neuropathy. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Chaouki, F., Djenfi, T., Roughi, M. F. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Simplified questionnaire for detecting patients with severe OSA
Conclusions: The simplified questionnaire could be a useful tool for detecting severe OSA patients who need immediately treatment in community in a Chinese population. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Huang, C., Feng, Y., Wang, L., Xiang, X., Steier, J., Luo, Y. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Acceptance and cost-effectiveness of telemedicine in patients with obstructive sleep apnea: a single-center randomized controlled trial
This study explores the treatment acceptance rate and cost-effectiveness of the telemedicine model in the clinical diagnosis and treatment of adult patients with obstructive sleep apnea (OSA). Patients admitted to the sleep center for snoring were randomly divided into telemedicine and control groups. The acceptance rate of the auto-adjusted positive airway pressure (APAP) treatment, cost of patient visits, cost of time, and labor cost of doctors in the two groups were observed. A total of 57 subjects were included, with an average age of 40.12±11.73 years, including 47 males (82.5%); 26 of whom were in the telemedi...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Ou, Q., Pei, G., Lao, M., Wang, L., Xu, Y., Tan, J., Zheng, G. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Respiratory symptoms and access to physiotherapy in children with cerebral palsy in Albania
Conclusions: In Albania there is an unmet need to carry out a national cohort based study on the prevalence of CP, and respiratory symptoms in CP patients. These studies should also increase awareness among the policy makers to provide free medical services and treatment and social support for these patients. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Hoxha, M., Malaj, V., Prendi, E., Zappacosta, B. Tags: Physiotherapists Source Type: research
Psychosocial factors associated with short-term CPAP usage
Conclusions: In OSA, greater confidence, motivation, and symptom improvement may support short-term CPAP use. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Kaye, L., Vuong, V., Benjafield, A., Gupta, P., Barrett, M. Tags: Psychologists and behavioural scientists Source Type: research
Utility of overnight oximetry indices in the evaluation of children with suspected Obstructive Sleep Apnea
Conclusions: This study provides optimal cut-off values for ODI3 in differentiating PS from OSA. As overnight oximetry is cheap and widely available unlike PSG, it has the potential to be incorporated into cost-effective clinical decision making algorithms. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Koh, Y. Q., Pugalenthi, A., Tan, Y. H., Teoh, O. H., Cheng, Z. R., Cheng, D. T., Goh, A., Chay, O. M., Allen Jr, J. C., Tan, S. G., Lim, M., Tan, J., Thomas, B. Tags: Paediatric respiratory physiology and sleep Source Type: research
Evaluation of anxiety and depression in patients with obstructive sleep apnea syndrome
Conclusion: In our study, anxiety and depression are very common in OSA as well as non-OSA snoring patients and they are not associated with the severity of the disease (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: braham, y., Touil, I., Chaouch, E., Tabka, O., Bouchareb, S., Boujneh, S., Ben Mechlia, M., Boussoffara, L., Kneni, J., Boudawara, N., Tabka, o. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Severe Asthma and sleep disorders: a Severe Asthma Network Italy (SANI) analysis
Conclusions: the prevalence of sleep-disorders in the SANI registry is 26%. This cohort of patients had also moderate to severe rhinitis with nasal polyposis and functionally more stable but clinically more compromised asthma. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Ferri, S., Heffler, E., Puggioni, F., Paggiaro, P., Blasi, F., Canonica, G. W. Tags: Monitoring airway disease Source Type: research
Predictive factors of moderate to severe sleep apnea syndrome in heart failure
Conclusion Our study showed a high prevalence of moderate to severe SAS in HF mainly obstructive, and it was associated with Left ventricular hypertrophy and right ventricular dysfunction. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Abdellatif, s., Yangui, F., Antit, S., Cherif, H., Boufares, A., Mkaddem, S., Triki, M., Zakhama, L., Charfi, M. R. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Obstructive sleep apnea and ischemic ECG changes in Mauritius
Conclusion In this population-based sample, snoring individuals had a higher prevalence of high OSA risk compared with non-snorers. A high OSA-risk was associated with ischemic ECG changes among snorers. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Nilsson, U., Blomberg, A., Zimmet, P., Tuomilehto, J., Magliano, D., Alberti, G., Kowlessur, S., Shaw, J., Tamosiunas, A., Söderberg, S. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Prevalence and characteristics of sleep apnea syndrome in heart failure patients
Conclusion Our study showed a high prevalence of occult SAS in both types of HF mainly OSA in HFpEF and CSA in HFrEF reflecting its severity. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Yangui, F., Abdellatif, s., Antit, S., Cherif, H., Boufares, A., Mkaddem, S., Triki, M., Zakhama, L., Charfi, M. R. Tags: Clinical and epidemiological respiratory sleep medicine Source Type: research
Piloting the FOLLOW-PCD questionnaire: a clinical and research tool
Conclusion: The FOLLOW-PCD questionnaire showed good completeness, especially for symptoms. We will use these results together with the ongoing cognitive validation to refine the questionnaire to a final version.Funding: SNF PZ00P3_185923 (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Goutaki, M., Lam, Y. T., Papon, J.-F., Pedersen, E. S. L., Kuehni, C. E. Tags: Paediatric respiratory epidemiology Source Type: research
