Nailed It!
Removing a nail from a hand is only half the battle. Proper treatment and follow-up should be considered with all foreign bodies in the skin, especially the hand. Watch this video of Jeffrey Yucht, MD, removing a nail from a patient’s hand, and read more in the Procedural Pause blog at http://bit.ly/ProceduralPause. (Source: Emergency Medicine News - Video)
Source: Emergency Medicine News - Video - June 1, 2018 Category: Databases & Libraries Source Type: video

Ultrasound Takes a Bath
The ultrasound water bath for foreign bodies replaces the need for contact between the ultrasound transducer and the patient's skin, eliminating discomfort. Watch this video of Dedrick Luikens, DO, using a water bath to find foreign bodies in a patient’s hand, and read more in the Procedural Pause blog at http://bit.ly/ProceduralPause. (Source: Emergency Medicine News - Video)
Source: Emergency Medicine News - Video - April 27, 2018 Category: Databases & Libraries Source Type: video

Skin resident T cells in human health and disease
Immunology IG Seminar Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell ac...
Source: Videocast - All Events - April 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Immunonology IG Seminar: “ Skin resident T cells in human health and disease ”
Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell activation in inflammato...
Source: Videocast - All Events - April 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Under Your Skin: Molecules and Cells for Touch and Pain
The National Center for Complementary and Integrative Health (NCCIH) presents the integrative Medicine Research Lecture Series. The series provides overviews of the current state of research and practice involving complementary health approaches and explores perspectives on the emerging discipline of integrative medicine. Dr. Alexander Chesler, Ph.D., Principal Investigator, Section on Sensory Cells and Circuits Intramural Lab, NCCIH, is our guest speaker for this lecture. The somatosensory system enables us to detect touch, temperature and painful stimuli. By studying patients with a rare, inherited disease, Alexander Che...
Source: Videocast - All Events - February 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Control of Skin Immunity by Non-Immune Cells
Immunonology IG Seminar The skin is a barrier organ that is a frequent site of entry for numerous pathogens. The skin is able to resist infection through a variety of mechanisms including innate and adaptive immune responses. Resident memory T cells (TRM) are a recently appreciated subset of memory T cells that reside in the skin and are required for optimal protection against previously encountered pathogens. These cells also participate in a number of cutaneous autoimmune diseases including vitiligo, psoriasis and alopecia areata. The skin also contains several populations innate immune cells that provide pathogen protec...
Source: Videocast - All Events - October 3, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Iftikhar Hussain, MD - New Developments in Inflammatory Dermatologic and Respiratory Diseases: Clinical Highlights From Helsinki
New Developments in Inflammatory Dermatologic and Respiratory Diseases: Clinical Highlights From Helsinki (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - August 4, 2017 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Law of STAT fives, root orchestrators of lymphocyte homeostasis and function
Immunology Interest Group Seminar Series The transcription factor STAT5 is fundamental to the mammalian immune system. Operating downstream of cytokines and growth factors, it impacts all aspects of lymphocyte biology, from general cellular processes like proliferation and apoptosis, to specialized immunological programs like effector and regulatory T cell differentiation. Genetic studies in humans underscore its widespread influence as mutations of STAT5 or upstream activators manifest varied Alejandro Villarino, NIAMS, NIHimmunological phenotypes including immunodeficiency, autoimmunity and hematological malignancies. Mo...
Source: Videocast - All Events - June 20, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Interferon-induced transmembrane proteins block Zika virus infection and prevent a non-apoptotic, paraptosis-like cell death pathway
We report that ZIKV induces massive vacuolization followed by “ implosive ” cell death in human epithelial cells, primary skin fibroblasts and astrocytes, a phenomenon which is exacerbated when IFITM3 levels are low. It is reminiscent of paraptosis, a caspase-independent, non-apoptotic form of cell death associated with the formation of large cytoplasmic vacuoles. We further show that ZIKV-induced vacuoles are derived from the endoplasmic reticulum (ER) and dependent on the PI3K/Akt signaling axis. Inhibiting the Sec61 ER translocon in ZIKV-infected cells blocked vacuole formation and viral production. Our results prov...
Source: Videocast - All Events - June 12, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Epithelial molecules shaping immunosurveillance by local T cells
Immunology Interest Group Seminar Series The thesis of conventional immunology is centralized control whereby responses to infection within tissues are decided within lymph nodes, from which effector T lymphocytes are dispatched to quell regional disturbances. But this cannot explain the observation that many tissues at steady state are T cell-rich. Do such cells simply provide responses to infection or do they provide more generalized means to sustain tissue integrity and organ function? Likewise, how are such cells able to respond to acute stress but not drive constitutive tissue inflammation? And, how do immune cell –...
Source: Videocast - All Events - May 8, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

MPS Distinguished Lecture: Prof. Z. Bao (Stanford) on Skin-Inspired Electronic Materials & Devices
MPS Distinguished Lecture Series by Professor Zhenan Bao (Stanford University), on “Skin-Inspired Electronic Materials & Devices”, on April 24, 2017.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 4, 2017 Category: Science Source Type: video

The Hedgehog Pathway and the Race against Tumor Resistance
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Oro is a Professor of Dermatology, Associate Director of the Center for Definitive and Curative Medicine, a member of the Institute for Stem Cell Biology and Regenerative Medicine and the Stanford Cancer Institute at Stanford University, and the Cancer Biology and Stem Cell graduate student programs. He trained in the medical scientist program at the Salk Institute under Ron Evans lab, working on functions of novel orphan nuclear receptors in model systems. During Dermatology residency/fellowship in Matthew Scott ’ s lab at Stanford, he helped solidify the link ...
Source: Videocast - All Events - May 1, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Elucidating the regulation of antiviral immune responses in humans
Director's Seminar Series Research in the laboratory headed by Dr. Su is aimed at understanding the molecular regulation of human immune responses in vivo. The laboratory aims to identify the genetic underpinnings of patients who have rare inherited immunodeficiencies that present with virus infections. These patients serve as " experiments of nature " who can more broadly inform us as to what is happening in the healthy immune system. Viruses of particular interest include those that infect the skin such as herpes simplex virus, as well as systemic viruses such as Epstein-Barr virus, and more recently respiratory tract vi...
Source: Videocast - All Events - March 14, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Genetics and immunology of alopecia areata
NIH Director ’ s Wednesday Afternoon Lecture Series For the past 20 years, Dr. Christiano's research has focused on understanding the molecular processes that lead to inherited skin and hair disorders in humans. Her research career began with the discovery of genetic mutations associated with epidermolysis bullosa, a skin disease that causes severe blistering. Dr. Christiano's recent work has focused on the investigation of the underlying genetic causes of and identification of potential therapies for alopecia areata, an autoimmune form of hair loss.For more information go tohttps://oir.nih.gov/walsAir date: 3/1/2017 3...
Source: Videocast - All Events - February 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Merkel Cells and Merkel Cell Carcinoma
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Brownell is a Board Certified Dermatologist and a Fellow of the American Academy of Dermatology. He obtained degrees in electrical engineering and mathematics prior to undergoing MD/PhD training at Baylor College of Medicine. Dr. Brownell completed a dermatology residency at the New York University School of Medicine, and a postdoctoral research fellowship in the laboratory of Dr. Alexandra Joyner at the Sloan-Kettering Institute. On the clinical faculty at the Memorial Sloan-Kettering Cancer Center, his practice focused on patients with high-risk skin cancers. In...
Source: Videocast - All Events - September 20, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video