Merkel Cells and Merkel Cell Carcinoma

NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Brownell is a Board Certified Dermatologist and a Fellow of the American Academy of Dermatology. He obtained degrees in electrical engineering and mathematics prior to undergoing MD/PhD training at Baylor College of Medicine. Dr. Brownell completed a dermatology residency at the New York University School of Medicine, and a postdoctoral research fellowship in the laboratory of Dr. Alexandra Joyner at the Sloan-Kettering Institute. On the clinical faculty at the Memorial Sloan-Kettering Cancer Center, his practice focused on patients with high-risk skin cancers. In 2011, Dr. Brownell joined the Dermatology Branch in the NCI CCR where he is Head of the Cutaneous Development and Carcinogenesis Section. Dr. Brownell directs a research program investigating the development and maintenance of stem cells in normal skin, and the changes that occur during the formation of skin cancer. A current focus in the laboratory is the regulation of neuroendocrine cells (Merkel cells) in the skin and the oncogenomics of Merkel cell carcinoma. Dr. Brownell also conducts early phase clinical trials to identify novel therapeutic and prognostic targets for this uncommon but aggressive skin cancer.Air date: 9/23/2016 12:00:00 PM
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