Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises
Conditions: Sickle Cell Disease; Vaso-occlusive Pain Episode in Sickle Cell Disease; Acute Pain Interventions: Device: Virtual Reality Headset and Hand-Held Controllers; Other: Blindfolding and Noise Cancelling Sponsors: University of Maryland, Baltimore Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials
Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric
Conditions: Vaso-occlusive Crisis Interventions: Drug: Sufentanil Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials
Realizing Effectiveness Across Continents With Hydroxyurea
Conditions: Sickle Cell Disease; Children Interventions: Drug: Hydroxyurea; Drug: Hydroxyurea Sponsors: Children ' s Hospital Medical Center, Cincinnati; National Heart, Lung, and Blood Institute (NHLBI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
The Role of Endothelin 1 as a Marker of Renal Impairment in Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Diagnostic Test: urinary endothelin 1 Sponsors: Sohag University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Long-term Follow-up (LTFU) of Patients Treated With Genome-edited Autologous Hematopoietic Stem and Progenitor Cells (HSPC)
Conditions: Sickle Cell Disease Interventions: Other: OTQ923 Sponsors: Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2023 Category: Research Source Type: clinical trials
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
Conditions: Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including; Sickle Cell Disease; Cystic Fibrosis; Fragile X Syndrome; Proximal Spinal Muscular Atrophy; Myotonic Dystrophy; Muscular Dystrophy, Duchenne; Muscular Dystrophy, Becker; Neurofibromatosis-Noonan Syndrome; Huntington Disease; Hemophilia A; Hemophilia B; MODY2 Diabetes; X-Linked Hydrocephalus; Autosomal Recessive Polycystic Kidney Disease Interventions: Biological: Blood sample Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials
Non-myeloablative Phase I/II Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function
Conditions: Sickle Cell Disease Interventions: Combination Product: Cohort 1; Combination Product: Cohort 2 Sponsors: National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials
Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function
Conditions: Sickle Cell Disease Interventions: Combination Product: Cohort 1; Combination Product: Cohort 2 Sponsors: National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials
A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)
Conditions: Anemia, Sickle Cell Interventions: Drug: HBI-002 Sponsors: Hillhurst Biopharmaceuticals, Inc.; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
Predictors of Pain in Sickle Cell Disease
Conditions: Sickle Cell Disease; Chronic Pain Interventions: Other: Quantitative sensory testing Sponsors: Duke University; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2023 Category: Research Source Type: clinical trials
Development and Adaptation of I-STRONG for SCD
Conditions: Sickle Cell Disease Interventions: Behavioral: I-STRONG for SCD Sponsors: Emory University; National Center for Complementary and Integrative Health (NCCIH) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 1, 2023 Category: Research Source Type: clinical trials
NIH Researchers Work to Preserve Fertility for People Undergoing Gene Therapy
October 12, 2023 -- Researchers at the National Institutes of Health have created a novel gene therapy procedure that could preserve fertility in people with sickle cell disease and other genetic blood conditions. Infertility is a high-risk and... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 12, 2023 Category: Pharmaceuticals Source Type: clinical trials
Siplizumab for Sickle Cell Disease Transplant
Conditions: Anemia, Sickle Cell Interventions: Drug: Siplizumab; Procedure: Exchange Transfusion; Procedure: Total Body Irradiation; Procedure: Stem Cell Infusion; Drug: Cyclophosphamide 50mg; Drug: Mesna; Drug: Sirolimus Oral Tablet; Drug: Rituximab or Biosimilar Sponsors: Markus Mapara; ITB-Med LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Sickle Cell Children's Exercise Study (SuCCESs)
Conditions: Sickle Cell Disease Interventions: Behavioral: SuCCESs Sponsors: University of Maryland, Baltimore Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials
The Living With a Long-Term Condition Study
Conditions: Asthma; Atrial Fibrillation; Cancer; Cerebrovascular Disorders; Stroke; CKD; Copd; Fibromyalgia; Pain; Heart Diseases; Heart Disease Chronic; Dementia; Diabetes; Epilepsy; Heart Failure; High Blood Pressure; Hypertension; Hiv; AIDS; IBD; IBS; Liver Diseases; Long COVID; Lupus Erythematosus; Multiple Sclerosis; Obesity; Osteoarthritis; Arthritis; Rheumatoid Arthritis; Osteoporosis; Parkinson Disease; Sickle Cell Disease; Hepatitis; Endometriosis; PCOS; Neurological Disorder; POTS - Postural Orthostatic Tachycardia Syndrome; MND (Motor Neurone DIsease); Cystic Fibrosis; Migraine; Spondylitis; Celiac Disease; Hidr...
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials
