Clinical Study of BRL-101 in Severe SCD
Conditions: Sickle Cell Disease Interventions: Drug: Autologous hematopoietic stem and progenitor cells injection Sponsors: Bioray Laboratories; First Affiliated Hospital of Guangxi Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Effect of Empowerment-Based Interventions on Self-Efficacy and Self-Care Capacity Among Adults With Sickle Cell Disease
Conditions: Self-Efficacy; Self-Care Interventions: Behavioral: Empowerment-Based Interventions; Behavioral: Standard Health Education Sponsors: University of Bahrain Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Patient and Public Involvement and Engagement in Research With Children and Young People With Sickle Cell Disorder and Their Families
Conditions: Sickle Cell Disease Sponsors: King ' s College London; Sickle Cell Society Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
Conditions: Anemia, Sickle Cell Interventions: Behavioral: SCThrive; Other: SCHealthED Sponsors: Children ' s Hospital Medical Center, Cincinnati; Nemours Children ' s Health System; Emory University; Children ' s Hospital of Philadelphia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Drug: BRL-101 autologous hematopoietic stem and progenitor cells injection Sponsors: Bioray Laboratories; Hospital of Hematology, Chinese Academy of Medical Sciences (Institute of Hematology, Chinese Academy of Medical Sciences) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Clinical Study of BRL-101 in the Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Drug: BRL-101 autologous hematopoietic stem and progenitor cells injection Sponsors: Bioray Laboratories; Nanfang Hospital, Southern Medical Universit Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy
Conditions: Sickle Cell Disease; Nephropathy Interventions: Drug: Mitapivat Sponsors: Agios Pharmaceuticals, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Conditions: Sickle Cell Disease; Vitamin D Deficiency; Health Related Quality of Life; Hand Grip Strength; Bone Mineral Density Interventions: Drug: Vitamin D3 Sponsors: Zagazig University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness
Conditions: Sickle Cell Disease Interventions: Behavioral: Video Directly Observed Therapy (VDOT); Behavioral: Health Reminder Tip Alerts Sponsors: Nationwide Children ' s Hospital; Ann& Robert H Lurie Children ' s Hospital of Chicago; Hasbro Children ' s Hospital; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 19, 2024 Category: Research Source Type: clinical trials
Zinc Supplementation in Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Drug: 25 mg/day zinc; Drug: 40 mg/day zinc Sponsors: University of California, San Francisco; American Society Hematology, Research Collaborative; Children ' s Hospital of Philadelphia; Johns Hopkins University; Baylor College of Medicine; Children ' s National Research Institute; Children ' s Hospital Medical Center, Cincinnati; Newark Beth Israel Medical Center; University of Pennsylvania Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 15, 2024 Category: Research Source Type: clinical trials
European Rare Blood Disorders Platform (ENROL)
Conditions: Anemia; Bone Marrow Failure; Bleeding Disorder; Iron Metabolism Disorders; Myeloma; Lymphoid Neoplasm; Myeloma, Malignant; Leukemia; Anemia, Sickle Cell; Thalassemia; Blood Cancer; Red Cell Membrane and Enzyme Abnormalities Interventions: Other: Collection of clinical and laboratory data from EHR. Sponsors: Hospital Universitari Vall d ' Hebron Research Institute; ERN-EuroBloodNet (European Reference Network on Rare Hematological Diseases Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials
Support Strategies for Parents During the First Year Following Their Child's Diagnosis of Sickle Cell Disorder
Conditions: Sickle Cell Disease Sponsors: King ' s College London; British Academy; Sickle Cell Society; King ' s College Hospital NHS Trust; Guy ' s and St Thomas ' NHS Foundation Trust Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials
Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell Disease
Conditions: Acute Chest Syndrome Interventions: Procedure: Red blood cell EXchange (REX) Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)
Conditions: Sickle Cell Disease; Thalassemia; Hemolytic; Anemia, Hereditary, Due to Enzyme Disorder; Anemia Due to Membrane Defect; CDA; Sideroblastic Anemia; Constitutional Aplastic Anemia; Iron Metabolism Disorders; Hereditary Anemia Interventions: Other: Data collection from EHR. Sponsors: Hospital Universitari Vall d ' Hebron Research Institute; Erasme University Hospital; Cyprus Institute of Neurology and Genetics; EuroBloodNet Association Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials
A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Drug: Etavopivat Sponsors: Forma Therapeutics, Inc.; Novo Nordisk A/S Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
