Why Don't Biotech Investors Run Replication Studies Before Investing?
Ichor Life Sciences is one of the earliest longevity industry companies, an interesting mix of contract research organization (CRO), biotech working on several different therapeutics, and investor in very early stage biotech startups. One of the Ichor co-founders here offers an interesting, though possibly biased perspective on how investors should behave in the biotech space. Inside companies, every new development program in the biotech industry starts with an attempt to replicate the research results that form the basis for the program, even given the existence of detailed, published papers and a coven of accessible res...
Source: Fight Aging! - February 28, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Amie Fornah Sankoh Achieves a Scientific Dream
Credit: LinkedIn.
“I wanted to give up so many times. Although I tried to remain positive, I never thought I’d be able to finish my Ph.D. But I made it, and I’m extremely proud of myself,” says Amie Fornah Sankoh, Ph.D., a research scientist with Dow Chemical Company who received NIGMS support as a graduate student.
Human and Plant Communication
Dr. Sankoh has loved science and mathematics since she was just a child growing up in Sierra Leone. When she was 3 years old, Dr. Sankoh became deaf from a childhood disease. Math, unlike other subjects, is very visual, which played a part in her interest in it. “...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 28, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Profiles Training Source Type: blogs
When it comes to Lepidoptera, plus ça change
An analysis of the genomes of more than 200 butterfly and moth, Lepidoptera, species reveals that genetic framework of what is ostensibly a very diverse group of insects, has remained remarkably stable since they diverged from their last common ancestor over 250 million years ago.
In a study published in the journal Nature Ecology and Evolution, shed new light on the evolutionary history and genetic structure of the Lepidoptera, which could help in conservation efforts for what is an incredibly important group of pollinators, food source for birds, bats, and other creatures, and a vital part of a healthy ecosystem and env...
Source: David Bradley Sciencebase - Songs, Snaps, Science - February 28, 2024 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs
From Breakthroughs to Best Practices: How NIMH Transforms Research Into Real-World Care
In this guest-written Director ’s message, the Division of Services and Intervention Research (DSIR) describes notable successes in bridging the gap between basic and clinical science and impacting real-world public health practices and policies. (Source: NIMH Directors Blog)
Source: NIMH Directors Blog - February 26, 2024 Category: Psychiatry Authors: National Institute of Mental Health Source Type: blogs
Telomere Length as a Target for Therapy
Average telomere length in a tissue is some reflection of (a) stem cell activity and (b) pace of cell division. Telomeres, repeated DNA sequences at the ends of chromosomes, lose some of their length with each cell division, and cells self-destruct or become senescent when telomeres become too short. This limits the ability of somatic cells to replicate, reducing the odds that a given cell will mutate to become cancerous by imposing a limit on cell activity and cell life span, enforcing turnover of cells in tissues. Stem cells, in comparison, are a small, well protected, privileged set of cell populations that use telomera...
Source: Fight Aging! - February 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Generative AI in Your Desk Drawer: Back Office Applications in Health Care
This article delineates the advantage of generative AI over earlier forms of AI and machine learning. We’ll look at several areas in health care where generative AI is in use, and discuss ways to make it widely available to small clinical organizations with few resources. We’ll also see how different organizations are training their models for maximum accuracy and value.
The Generative AI Advantage
The impacts of generative AI throughout society will be hard to assess for some time because it is so new and has become the darling of computer science so fast. Stepro describes the pace of change as “extrem...
Source: EMR and HIPAA - February 26, 2024 Category: Information Technology Authors: Andy Oram Tags: Administration AI/Machine Learning C-Suite Leadership Health IT Company Healthcare IT Administrative Burden Amazon Web Services Arcadia Artificial Intelligence AWS Back Office Bikham Caen Contee ChatGPT David Kereiakes Gauri Source Type: blogs
Beware the March dagger
In the world of entomology, the naming conventions of moth species often reflect a fascinating interplay between scientific and vernacular language. While some moth species boast evocative common names like Angle Shades or Setaceous Hebrew Character, others, particularly those belonging to the category of micro moths, are identified solely by their scientific nomenclature, lacking universally recognized common names. This situation draws a curious parallel to the realm of dinosaurs, where species like Tyrannosaurus rex are known exclusively by their scientific designations.
Diurnea fagella moth
However, amidst this taxonom...
Source: David Bradley Sciencebase - Songs, Snaps, Science - February 26, 2024 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs
Bonus Features – February 25, 2024 – 73% of digital health vendors use FHIR APIs, 83% of clinicians think telemedicine is good for chronic condition management, plus 28 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
U.S. Reps Mike Kelly (R-PA) and Bill Foster (D-IL) introduced the Patient Matching and Transparency in Certified Health IT (MATCH IT) Act of 2024, which would standardize the way demographic information is entered into cer...
Source: EMR and HIPAA - February 25, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Accenture Authenticx Availity AXYS Biofourmis Brightside Health Dandelion Health Digital Health Collaborative Edifecs EHR Association Experity FHIR API Healthcare IT Today Bonus Features Healthcare Legislation H Source Type: blogs
Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition.
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Reviewing the Development of Senotherapeutics to Treat Aging
https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/
Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Update on Kimer Med, Improving on the DRACO Antiviral Technology and Moving Towards the Clinic
The state of anti-viral therapies isn't that great, all things considered. Technology has not yet advanced to the point at which a viral infection can be simply shut down, as is the case for near all bacterial infections. The present anti-viral drugs are either vaccines (useful!) or merely shift the odds somewhat by interfering in some part of the viral life cycle, but nowhere near as effectively as desired. Many persistent viral infections are thought to contribute meaningfully to forms of age-related dysfunction, and there is too little that can be done about that at the present time.
This landscape is one of the ...
Source: Fight Aging! - February 23, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Health IT Trends that Deserve More Attention
There are a lot of new ideas and technologies being made to better the world of healthcare. These new ideas and technologies are only successful, however, if enough people collectively take notice and talk about it in order to make it trend. But in a time when our industry is facing high staff overtime and burnout, there’s simply no way that we can be aware of everything happening in health IT. This then results in certain topics being neglected – regardless of their quality and how much you would personally like to see them trend.
So what trend isn’t being talked about enough? What should be trending ri...
Source: EMR and HIPAA - February 23, 2024 Category: Information Technology Authors: Grayson Miller Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Arcadia Ariel Gamiño Bobbi Weber CliniComp Colin Banas Dr. Lawrence Werlin DrFirst Epocrates Health IT Trends Heather Bassett HRC Fertility Joan But Source Type: blogs
Digital Health, Menopause, And The $150 Billion Ignorance
The idea of this story came from personal experience. During the past year, I have spent countless hours and a bucketload of money trying to figure out what the heck is wrong with my health. I was feeling worse and worse, having various symptoms, totally inexplicable with my impeccable test results. During this journey, not a single doctor asked or suggested that my symptoms may come from entering perimenopause – the stage of life of women preceding menopause.
I am 47 years old, and as I have learned since then, extremely average in starting to have perimenopause symptoms at the age of 47. Also very average ...
Source: The Medical Futurist - February 22, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Lifestyle medicine female health menopause tech Source Type: blogs
A Popular Science View of Recent Thinking on DNA Damage as a Cause of Aging
There are presently two views of the way in which stochastic DNA damage can contribute to aging. Most DNA damage occurs in inactive genes in cells that will not replicate many more times, and thus cannot possibly produce systemic consequences throughout large regions of the body. The first argument for a way in which random DNA damage can produce a broader effect is via somatic mosaicism, in which mutational damage occurs in stem cells, allowing those mutations to spread throughout tissue over time. It is unclear as to how to measure the contribution of this process to age-related loss of function, however, and its contrib...
Source: Fight Aging! - February 21, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
How many songs is too many songs?
As with guitars, you can never have too many songs, surely? My modern period of writing and recording began around April 2012, although I’d done a lot of noodling guitar instrumentals with beats and synths for many years before that going way back into my teens.
But, this modern period which started in my 40s when I co-established an Arts Night happening got me writing and recording on a more regular and frequent basis. Some of the early stuff is lost to my old SoundCloud page. That said, I could probably resurrect those files if there was a demand. There were also dozens of cover versions, some of which are still o...
Source: David Bradley Sciencebase - Songs, Snaps, Science - February 21, 2024 Category: Science Authors: David Bradley Tags: Music Source Type: blogs
Developing Low-Cost Lab Techniques: Q & A With Abraham Badu-Tawiah
Credit: Ohio State University.
“I never thought I could make an impact on chemistry and students’ lives. But now, I’m the head of a lab with several Ph.D. and undergraduate students and a postdoctoral researcher; and we’re developing simple, low-cost lab techniques that can be adopted by labs across the world,” says Abraham Badu-Tawiah, Ph.D., the Robert K. Fox Professor of Chemistry at Ohio State University in Columbus. We talked with Dr. Badu-Tawiah about his career progression, research, and advice for students hoping to launch a career in science.
Q: How did you get started on the path to a career in sci...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 21, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Profiles Source Type: blogs
