Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Culling in the name of …
If you have even a passing interest in the natural world, you will have most likely heard the phrase “invasive species”. By definition, a deliberate or accidental release of a species to an area beyond its natural environment where it then multiplies and causes damage to that environment and the native wildlife that relies on it. I discussed the UK issue of invasive species briefly last year and in the context of Muntjac and Black Hairstreak butterfly too.
Ecologist and conservationist Hugh Warwick tackles the issue in much more depth in his latest book – Cull of the Wild. Warwick is, as most of us are, ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 12, 2024 Category: Science Authors: David Bradley Tags: Biology Environment Science Source Type: blogs
Pulse of Progress: Looking Back, Moving Forward | TAPP 147
In Episode 147, host Kevin Patton reviews thehighlights and events of theprevious year in theworld of The A&P Professor. He then turns to last year ' s predictions for teaching human anatomy and physiology to see if he was on the right track. Finally,predictions for the coming year are revealed. And lots of other stuff —this episode istwo hours long, after all!0:00:00 | Introduction0:00:50 | Debrief: Topics, Stats, Reflections0:21:28 | A Long, Long, Long Episode0:23:05 | Debrief: More Reviewing& Reflecting0:38:59 | Did I Get My Predictions Right?0:50:22 | Textbook& Academic Authors Association0:57:47 | Lookin...
Source: The A and P Professor - April 12, 2024 Category: Physiology Authors: Kevin Patton Source Type: blogs
SENS Research Foundation and Lifespan.io to Merge
Merging the non-profits SENS Research Foundation and Lifespan.io is one of those ideas that makes a lot of sense in hindsight. SENS Research Foundation is research focused and very much interested in expanding into patient advocacy, as it depends on philanthropic funding. Lifespan.io is a patient advocacy organization that is very much interested into expanding into helping to advance the science of aging and clinical trials for therapies of aging. They complement one another, and may well produce greater gains as one organization than as two.
Lifespan.io, renowned for its unwavering advocacy for longevity and res...
Source: Fight Aging! - April 11, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Political Science
I always do my best to write clearly and precisely, but it seems I don ' t always manage to get my meaning across. So let ' s try a couple of ideas again. Please read carefully, and think about what I actually write, not what you think I might think or what other people think. The First Amendment applies only to government. It constrains what government can do, it does not place any constraint of any kind on any other entity. The courts have interpreted it a bit more broadly than its literal language. If " congress shall make no law . . . " then the executive cannot have any legal authority to do what no law permits. ...
Source: Stayin' Alive - April 10, 2024 Category: American Health Source Type: blogs
Martin Burke: Replacing Lost Proteins to Treat Disease
As a medical student, Martin Burke, M.D., Ph.D., helped care for a young college student with cystic fibrosis (CF), an inherited disease that affects the body’s ability to make sweat and mucus. Dr. Burke had just studied CF in class, so he relayed what he had learned to her. He had a lot of information to give—doctors and researchers know the exact amino acid changes in an ion channel protein called cystic fibrosis transmembrane conductance regulator (CFTR) that cause CF.
Credit: UIUC News Bureau, Fred Zwicky.
“At one point in the conversation, she stopped me and said, ‘It sounds like you know exactly what’s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 10, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Medicines Profiles Source Type: blogs
Novel mTOR Inhibitors Viewed as a Safer Option by Conservative Investors
The safest sort of investment into therapeutic development is one made in a part of a field that is well established, producing a small variant of an existing drug, using the well beaten path of small molecule development, targeting a mechanism that is very well understood, and that has extensive safety data associated with it. One could argue that mTOR inhibition is the canonical example of a low risk investment in the longevity field. Like most lower-risk exercises in medical development, the potential gain for patients is modest. mTOR inhibition can produce larger gains in mouse life span than exercise, but doesn't beat...
Source: Fight Aging! - April 8, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Can Digital Technologies Help Overcome Diabetes? An Assessment of the Recent PHTI Review
Payers are always wary about funding new treatments for illnesses and conditions: When millions of dollars are at stake, payers want demonstrated improvements in outcomes. So do doctors and patients, before they go through the trouble of adopting a course of treatment. So there was much consternation recently when the Peterson Health Technology Institute (PHTI) released a report saying that digital interventions weren’t helping people with diabetes much and weren’t worth their added costs.
PHTI has a comprehensive and detailed assessment framework that it applies to health care technologies to determine whether...
Source: EMR and HIPAA - April 8, 2024 Category: Information Technology Authors: Andy Oram Tags: Clinical Health IT Company Healthcare IT Telemedicine and Remote Monitoring A1c ANdy Molnar Behavior Change Behavior Health CGM Continuous Glucose Monitoring Dario Health diabetes Diabetes Monitoring Digital Health Digital Ther Source Type: blogs
Linus Health Acquires Aural Analytics
Purchase Expands Linus Health’s Cognitive Assessment Capabilities
Linus Health, a digital health company enabling early detection of Alzheimer’s and other dementias, today announced it has acquired Aural Analytics, a leader in clinical-grade speech analytics. The deal includes Aural Analytics’ assets, including its technology and intellectual property.
With the acquisition of Aural Analytics, Linus Health, the leader in multimodal cognitive assessments, has added clinical-grade speech analytics to its platform. This allows Linus Health to further enable researchers and clinicians to identify cognitive impairment and ...
Source: EMR and HIPAA - April 8, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alvaro Pascual-Leone Aural Analytics David Bates Digital Cognition Technologies Health IT Acquisitions Healthcare M&A Kinesis Health Technologies Linus Health Source Type: blogs
Complexity and chronic pain*
*Persistent didn’t alliterate so well!
I’ve been pondering what makes persistent pain so complicated? What is it about this problem that means clinicians use terms like ‘heart-sink’, or ‘problematic’, or ‘difficult’ when they talk about people living with pain?
While nociception and all the associated neurobiological processes associated with pain are undoubtedly complex (and poorly understood), I don’t think this is what people mean when they describe chronic pain is complex. After all, there are loads of body systems and disease processes that are complex.
I...
Source: HealthSkills Weblog - April 7, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Professional topics Science in practice healthcare pain management Source Type: blogs
Famous Connections – a new parlour game
I’m sure someone will tell me this has been done, but having come up with a silly meme idea on Twitter, I was thinking of a game that’s a hybrid between Six Degrees of Separation and Mornington Crescent.
Title: Famous Connections
Objective: To be the last player holding all the chips
Players: Four or more
Materials: Ten chips per player, a designated referee, a timer
Setup: Each player starts with ten chips. All players contribute one chip to the kitty
Gameplay: The player deemed oldest/youngest/tallest/shortest begins the game. The starting player states a famous name from any field, real or fictional. The n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 5, 2024 Category: Science Authors: David Bradley Tags: Education Fiction Source Type: blogs
I Think We Still Have A Great Deal To Learn About The Denisovans …
This
appeared last week
The
Observer Evolution
Scientists link elusive human group to 150,000-year-old Chinese ‘dragon
man’
Researchers have found fresh evidence that may connect the mysterious
Denisovans to the early human species Homo longi
Robin
McKie Science editor
Sun 31 Mar 2024 02.00 AEDT Last modified on Sun 31 Mar 2024
07.16 AEDT
They remain one of the most elusive groups of (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - April 5, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
More on Freeze Peach
This is a topic I address from time to time, but it seems a new post is needed now because of various nonsense that ' s going on. First, let me make one thing perfectly clear, as a man we would all like to forget used to say: free speech and academic freedom are not the same. Legally, the only meaning of Free Speech ™ is the First Amendment, as interpreted by the courts. Originally it applied only to the federal government, but the 14th Amendment extended the protections of the Bill of Rights to the States, so it now applies to all government entities within the United States, and that includes your small tow n Board of ...
Source: Stayin' Alive - April 4, 2024 Category: American Health Source Type: blogs
Will Medical Facial Recognition Technology (mFRT) Reawaken Eugenics?
By MIKE MAGEE
How comfortable is the FDA and Medical Ethics community with a new super-charged medical Facial Recognition Technology (mFRT) that claims it can “identify the early stages of autism in infants as young as 12 months?” That test already has a name -the RightEye GeoPref Autism Test. Its’ UC San Diego designer says it was 86% accurate in testing 400 infants and toddlers.
Or how about Face2Gene which claims its’ mFRT tool already has linked half of the known human genetic syndromes to “facial patterns?”
Or how about employers using mFRT facial and speech patterns to identify employees likely t...
Source: The Health Care Blog - April 4, 2024 Category: Consumer Health News Authors: matthew holt Tags: Uncategorized Source Type: blogs
Technobabble To English: A Buzzword Guide For Medical AI And Digital Health
Navigating AI in medicine and digital health can feel like ordering a coffee at that new hipster café downtown: exciting yet slightly overwhelming with a menu that seems to be in a different language. A while ago we published a buzzword dictionary to help you decode the most frequently repeated terms. Back then artificial intelligence and machine learning were rarely heard exotic expressions, but as quite a few years have passed, a whole new set of mambo-jambo emerged, waiting to be explained.
You’re probably sick of hearing the latest digital health buzzwords without any actual context, so let’s translat...
Source: The Medical Futurist - April 4, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine buzzword AI in medicine generative AI in medicine Source Type: blogs
