Age-Related Neuroinflammation and the Development of Neurodegenerative Conditions
The research community now considers chronic inflammation in brain tissue to be an important aspect of the development of neurodegenerative conditions. Unresolved inflammatory signaling is disruptive of tissue structure and function. With age, a state of chronic inflammation arises due to the presence of senescent cells, the reaction of the innate immune system to debris from stressed cells and metabolic waste such as protein aggregates, persistent viral infection, and a range of other contributing mechanisms. Therapies - such as senolytic treatments to clear senescent cells - that can suppress excess inflammation without ...
Source: Fight Aging! - January 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Sleep Is At The Heart Of Almost All Mental Health Issues (M)
Whether it is anxiety, schizophrenia, Tourette's or depression, all have circadian rhythm disruption in common. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 30, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Mental Health Sleep subscribers-only Source Type: blogs
Fight Aging! Newsletter, December 26th 2022
This article on senolytic therapies to selectively remove senescent cells in old tissues is in part a matter of Unity Biotechnology talking up their position. The company suffered from first mover disadvantage in bringing senolytic drugs into clinical development. The field has made progress very rapidly over the last decade, and startups founded even just a couple of years after Unity's launch benefited from greater knowledge and a selection of better technologies to work with. Still, one can be talking up one's position and also be right. The accumulation of senescent cells is profoundly harmful, a significant contributi...
Source: Fight Aging! - December 25, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Somatic Mosaicism in the Aging Brain
Somatic mosaicism is the result of the random mutational damage that occurs to stem cells and progenitor cells, leading to a spread of different mutation patterns throughout the descendant cells making up a tissue. It is thought to be involved in aging, a way for random mutation, different in every cell, to lead to specific dysfunctions occurring throughout a tissue, and potentially prime a tissue for a later combination of mutations that gives rise to cancer. This commentary on recent research discusses somatic mosaicism in the brain, intending to see whether there were differences in neurological disease states, but the ...
Source: Fight Aging! - December 20, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Study identifies cognitive benefits of ketamine in patients with treatment-resistant depression
This article is based on the results of “Evaluation of Early Ketamine Effects on Belief-Updating Biases in Patients With Treatment-Resistant Depression”, recently published in JAMA Psychiatry. The article was originally published on The Conversation and translated from the French by Enda Boorman for Fast ForWord.
To Learn More:
FDA-approved, Cybin-sponsored clinicial trial to measure ketamine’s impact on the brain via Kernel Flow neuroimaging helmet
Study: Psychedelics can promote neural plasticity in the prefrontal cortex and expand pathways for mental health
The post Study identifies cognitive benefits of ketamin...
Source: SharpBrains - December 8, 2022 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health affective bias antidepressants augmented psychotherapy brain-activity Brain-Plasticity Cognitive Neuroscience depression depressive beliefs ketamine NMDA pharmacological psilocybin psychedelic medicine psyc Source Type: blogs
“Just Plain Actin’ Crazy” – A Quick Guide to Abnormal Behavior
I’m not going to beat around the bush about this. We deal with some folks who act weird. First you have the folks that you work with. As a group the EMS community can be a bit on the strange side. But right now I’m talking about our patients.
The spectrum of odd human behavior can be so vast that we are often at a loss to classify the patients presentation. It can be difficult to separate the delusion from the hallucination and the paranoia from the psychosis. Was that an episode of hysteria or mania? Here’s a quick guide to the clinical definitions of these terms that we kick around when our patient’s...
Source: The EMT Spot - November 14, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
" And then a Plank in Reason, broke, "
“I am dead.” In terms of possible delusions in living human beings,Le d élire des négations—the nihilistic delusion that one is dead —evokes the most harrowing existence imaginable. The French neurologistJules Cotard first described the syndrome that bears his name (1882,English translation):I hazard the name ofdelirium of negations to designate the state of the patients ... in whom the negative disposition is carried to the highest degree. [They are] asked their name – they have no name; their age – they are ageless; where were they born – they were not born; ... if they have a headache, s...
Source: The Neurocritic - September 30, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Can Amazon Capitalize on its Purchase of One Medical? Four Steps Toward Analytical Success
There’s naturally a lot of buzz over the acquisition of One Medical by Amazon.com. All the big tech companies are convinced they can fix our health care system. Perhaps they will start serving up appropriate treatments the way they choose the movies we view or the political diatribes we consume. But I recently talked to Gus Malezis, CEO of the digital identity company Imprivata, to explore what Amazon has to do to make its investment pay off.
Malezis pointed out that healthcare landscape is strewn with high-tech failures such as IBM Watson and Google Health. Patient data is just too scattered, too inaccurate, and too...
Source: EMR and HIPAA - September 16, 2022 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Health IT Company Healthcare IT Hospital - Health System Interoperability Amazon Amazon Healthcare Google Health Gus Malezis Healthcare Data IBM Watson Imprivata One Medical patient data Source Type: blogs
AI Startup AESOP Raises $3M to Tackle Medical and Billing Errors
Digital health startup AESOP Technology has raised a $2.95 million series pre-A round to address the growing medical and billing errors problem. The round was led by Taiwania Capital with participation from Colopl Next, 500 Startups, and BE Capital.
Originally from Taiwan, AESOP started as a university spin-off from Taipei Medical University (TMU). Professor Yu Chuan (Jack) Li, the founder and current president at the International Medical Informatics Association, spent ten years before AESOP working on big data approaches to reduce medication errors. He initially applied the model to launch a product, RxPrime (previo...
Source: EMR and HIPAA - September 13, 2022 Category: Information Technology Authors: Healthcare IT News Tags: AI/Machine Learning Health IT Company Healthcare IT 500 Startups AESOP AESOP Technology BE Capital Colopl Next Dr. Jeremiah Scholl Dr. Jim Long DxPrime Health IT Funding Health IT Fundings Health IT Investment International Med Source Type: blogs
The 2 Most Disabling Mental Health Conditions
The study compared 18 different mental health problems and substance use disorders. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 27, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Personality Schizophrenia Source Type: blogs
The Nurse as Tireless Patient Advocate
As highly respected healthcare professionals who often go above and beyond the call of duty, nurses are natural patient advocates. The nursing process may begin with assessment, but where the rubber hits the road is when nurses go to bat for their patients to make sure they receive the best possible care when they need it most. &...
Source: Digital Doorway - August 22, 2022 Category: Nursing Source Type: blogs
The Childhood Events That Can Trigger Schizophrenia Symptoms (M)
Schizophrenia may occur on a spectrum, like autism, with some people experiencing transient symptoms. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 12, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Child Psychology Schizophrenia subscribers-only Source Type: blogs
Bonus Features – July 3, 3022 – Judge says Apple infringed AliveCor ’ s patent, more than half of patients have trouble managing their records, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
An International Trade Commission (ITC) judge has ruled that Apple infringed AliveCor’s patented personal electrocardiogram technology. The judge’s decision follows two complaints that AliveCor filed against App...
Source: EMR and HIPAA - July 3, 2022 Category: Information Technology Authors: Brian Eastwood Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AliveCor Andy Powell Apple Autonomous Revenue Cycle Management Cedar Gate Technologies DarioHealth DrFirst ECG Patents Harmony Health IT Healthcare IT To Source Type: blogs
Large neuroimaging study finds social isolation to be an early indicator of increased dementia risk
This article was originally published on The Conversation.
To Learn More:
The neuroscience behind why our brains will need time to adjust to ‘un-social distancing’
Can you grow your hippocampus? Yes. Here’s how, and why it matters
Three ways to protect your mental health during –and after– COVID-19
The post Large neuroimaging study finds social isolation to be an early indicator of increased dementia risk appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - June 23, 2022 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health brain-structure chronic-stress cognition cognitive cognitive thinking cognitive-reserve cognitive-tasks frontal-lobe hippocampus human-brain memory neuroimaging neuroscience physical-health reaction-time Source Type: blogs
Season of birth is not related to risk of developing anxiety or depression
By Emily Reynolds
A new study has cast doubt on historic research suggesting that the season or month of someone’s birth is associated with an increased risk of certain mental health conditions.
The paper, published in Scientific Reports, looks at symptoms of anxiety and depression among more than 70,000 older adults in Europe. And it finds that there is no relationship between when they were born and the likelihood that they experience anxiety or depression.
A number of past studies have found a link between season of birth and mental health diagnoses: research has linked bipolar disorder and schizophrenia...
Source: BPS RESEARCH DIGEST - June 8, 2022 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Developmental Mental health Source Type: blogs
