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Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202332. Online ahead of print.ABSTRACTWe aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance imaging. Men with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers (Queen Mary Hospital and Princess Margaret Hospital, Hong Kong, China) between January 2017 and June 2022 were included. Ultrasound-magnetic resonance imaging fusion biopsies were performed a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun Rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho Ip Ada Tsui-Lin Ng Yiu-Chung Lam Source Type: research
The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research
Sperm acrosin activity may be a useful factor in choosing between ICSI and IVF for infertile male patients
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202337. Online ahead of print.ABSTRACTThe clinical applications of acrosin activity are limited. We analyzed 61 578 male partners in infertile couples who visited the outpatient department of the Reproductive and Genetic Hospital of CITIC-Xiangya (Changsha, China) between August 2014 and December 2019 to determine the reference ranges and thresholds for acrosin activity in infertile Chinese men; to determine whether correlations exist between acrosin activity and age, sperm concentration, sperm morphology, or sperm motility; and to evaluate whether acrosin activity could serve a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Ye-Na Hu Liang Hu Xin-Yu Yin Huan Zhang Yang-Qin Peng Gang Liu Ge Lin Wei-Na Li Source Type: research
Clinical, Virological, and Immunological Features in Cosmopolitan Genotype DENV-2-Infected Patients during a Large Dengue Outbreak in Sri Lanka in 2017
In this study, we characterized the DENV-2 cosmopolitan genotype from patients during this epidemic. Also, we identified host factors that contributed to the severity of dengue infection in patients infected with this particular virus. Ninety-one acute serum samples from patients at the National Hospital in Kandy were randomly selected. Of these, 40.2% and 48.9% were positive for dengue IgM and IgG, respectively. NS1 antigen levels were significantly higher in primary infections. The severe dengue (SD) and dengue with warning signs (DWWS) groups exhibited significantly higher viral genome and infectivity titers than the de...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Khine Mya Nwe Mya Myat Ngwe Tun Rohitha Muthugala Takeshi Nabeshima Jean Claude Balingit Lakmali Rajamanthri Dulani Jayawardana Shanthi Attanayake Shingo Inoue Yuki Takamatsu Takeshi Urano Kouichi Morita Source Type: research
Case Report: Outbreak of Nosocomial Myiasis by Cochliomyia macellaria (Diptera, Calliphoridae) in a Hospital in Colima, Mexico
Am J Trop Med Hyg. 2023 Sep 11:tpmd220225. doi: 10.4269/ajtmh.22-0225. Online ahead of print.ABSTRACTMyiasis in humans is a disease caused by larvae of various fly families. It mainly occurs in communities with poor sanitation and low socioeconomic status. Meanwhile intrahospital or nosocomial myiasis represents a rare phenomenon but is of relevance to public health. Here, we report an outbreak of myiasis caused by Cochliomyia macellaria in five patients hospitalized for several diseases at the Service of Internal Medicine of the Hospital Regional Universitario de Colima, Mexico during June and July 2021. Three patients we...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Francisco Espinoza-G ómez Fabian Rojas-Larios Saulo Cruz-Sanchez Alejandrina Rodriguez-Hernandez Iv án Delgado-Enciso Source Type: research
Quality Improvement Initiative to Increase Modality Education in a Nephrology Clinic During the COVID-19 Pandemic
Nephrol Nurs J. 2023 Jul-Aug;50(4):313-320.ABSTRACTLow attendance by patients with advanced chronic kidney disease (CKD stage 4 and 5) to the kidney replacement therapy (KRT) education sessions was noted by our nurse practitioners at a safety net hospital. The main outcome measure was the weekly percentage of patients with advanced CKD seen by the nephrology division weekly that completed KRT education. Process measures were weekly KRT session attendance by scheduled patients and the weekly referral of patients to KRT education sessions. The weekly education class attendance by scheduled patients reached the target level. ...
Source: Nephrology Nursing Journal - September 11, 2023 Category: Nursing Authors: Suma Prakash Colleen Rabbitt Iryna Danylyuk Diane Woodford Rui Song Wayne Satz Jan Schriefer Source Type: research
Clinical, Virological, and Immunological Features in Cosmopolitan Genotype DENV-2-Infected Patients during a Large Dengue Outbreak in Sri Lanka in 2017
In this study, we characterized the DENV-2 cosmopolitan genotype from patients during this epidemic. Also, we identified host factors that contributed to the severity of dengue infection in patients infected with this particular virus. Ninety-one acute serum samples from patients at the National Hospital in Kandy were randomly selected. Of these, 40.2% and 48.9% were positive for dengue IgM and IgG, respectively. NS1 antigen levels were significantly higher in primary infections. The severe dengue (SD) and dengue with warning signs (DWWS) groups exhibited significantly higher viral genome and infectivity titers than the de...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Khine Mya Nwe Mya Myat Ngwe Tun Rohitha Muthugala Takeshi Nabeshima Jean Claude Balingit Lakmali Rajamanthri Dulani Jayawardana Shanthi Attanayake Shingo Inoue Yuki Takamatsu Takeshi Urano Kouichi Morita Source Type: research
Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202332. Online ahead of print.ABSTRACTWe aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance imaging. Men with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers (Queen Mary Hospital and Princess Margaret Hospital, Hong Kong, China) between January 2017 and June 2022 were included. Ultrasound-magnetic resonance imaging fusion biopsies were performed a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun Rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho Ip Ada Tsui-Lin Ng Yiu-Chung Lam Source Type: research
The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research
Sperm acrosin activity may be a useful factor in choosing between ICSI and IVF for infertile male patients
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202337. Online ahead of print.ABSTRACTThe clinical applications of acrosin activity are limited. We analyzed 61 578 male partners in infertile couples who visited the outpatient department of the Reproductive and Genetic Hospital of CITIC-Xiangya (Changsha, China) between August 2014 and December 2019 to determine the reference ranges and thresholds for acrosin activity in infertile Chinese men; to determine whether correlations exist between acrosin activity and age, sperm concentration, sperm morphology, or sperm motility; and to evaluate whether acrosin activity could serve a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Ye-Na Hu Liang Hu Xin-Yu Yin Huan Zhang Yang-Qin Peng Gang Liu Ge Lin Wei-Na Li Source Type: research
Quality Improvement Initiative to Increase Modality Education in a Nephrology Clinic During the COVID-19 Pandemic
Nephrol Nurs J. 2023 Jul-Aug;50(4):313-320.ABSTRACTLow attendance by patients with advanced chronic kidney disease (CKD stage 4 and 5) to the kidney replacement therapy (KRT) education sessions was noted by our nurse practitioners at a safety net hospital. The main outcome measure was the weekly percentage of patients with advanced CKD seen by the nephrology division weekly that completed KRT education. Process measures were weekly KRT session attendance by scheduled patients and the weekly referral of patients to KRT education sessions. The weekly education class attendance by scheduled patients reached the target level. ...
Source: Nephrology Nursing Journal - September 11, 2023 Category: Nursing Authors: Suma Prakash Colleen Rabbitt Iryna Danylyuk Diane Woodford Rui Song Wayne Satz Jan Schriefer Source Type: research
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Patient Adherence to Secondary Prevention Therapies After an Acute Coronary Syndrome: A Scoping Review
Clin Ther. 2023 Sep 8:S0149-2918(23)00314-4. doi: 10.1016/j.clinthera.2023.08.011. Online ahead of print.ABSTRACTPURPOSE: Adherence to guideline-recommended, long-term secondary preventative therapies among patients with acute coronary syndrome (ACS) is fundamental to improving long-term outcomes. The purpose of this scoping review was to provide a broad synopsis of pertinent studies in a structured and comprehensive way regarding factors that influence patient adherence to medical therapy after ACS.METHODS: Relevant articles focusing on adherence to medical therapy after ACS were retrieved from the EMBASE and MEDLINE data...
Source: Clinical Therapeutics - September 10, 2023 Category: Drugs & Pharmacology Authors: M Cecilia Bahit Serge Korjian Yazan Daaboul Suzanne Baron Deepak L Bhatt Arzu Kalayci Gerald Chi Paul Nara Alka Shaunik C Michael Gibson Source Type: research
Importance of screening severe COVID-19 patients for IFN- λ1, IL-6 and anti-S1 IgG levels
The objective of this study is to screen IFN-λ1, IL-6 and antibody levels in consecutive serum sample sets of COVID-19 patients. A total of 365 serum samples collected from 208 hospitalized COVID-19 patients were analyzed for IFN-λ1 and IL-6 levels as well as SARS-CoV-2 neutralizing antibodies and anti-S1 IgG antibodies. Analyses of serum samples for cytokine levels showed that IFN-λ1 (>8 pg/mL) and IL-6 (>2 pg/mL) were detected in approximately 64% and 21% patients, respectively. A decrement in IFN-λ1 levels and IL-6 levels above 35 pg/mL can be sign of clinical severity and upcoming dead. An increment in IL-6 l...
Source: Cytokine - September 10, 2023 Category: Molecular Biology Authors: Olcay Buse Kenano ğlu Ayt ül Gül H üseyin Can Muhammet Karakavuk Sedef Erkunt Alak G ülay Korukluoğlu Ay şe Başak Altaş H üsnü Pullukçu Aysu De ğirmenci Döşkaya Tu ğba Karakavuk Ceren G ül Candan Çiçek Mehmet Sezai Ta şbakan Ak ın Çi Source Type: research
Thromboembolic disease and cancer: Attitude and practice of general practitioners. A qualitative study
DISCUSSION: The question of etiology of cancer remains unanswered. General practioners would like to be made aware of a common, codified attitude. This raises the question of the applicability of the recommendations. The aim is to avoid misdiagnosing a cancer or delaying a diagnosis, while at the same time, not unnecessarily exposing certain patients to excessive investigations when these are not needed. So, it is time to think about better dissemination of recommendations, tools to help GPs easily finding what they need among the multitude of existing recommendations and tools, to establish better collaboration between ge...
Source: Bulletin du Cancer - September 10, 2023 Category: Cancer & Oncology Authors: Andr éa Barbarit Cyrielle Guyon Elodie Poupin Bernard Fr èche Source Type: research
