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Infectious Disease: Hepatitis
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Total 32452 results found since Jan 2013.
Hepatic safety and efficacy of immunomodulatory drugs used in patients with autoimmune hepatitis
CONCLUSION: Among 25 AIH patients who were treated with immunomodulatory drugs for different reasons, the majority had a fovorable course, relapse was frequent in difficult-to-treat patients who received belimumab, and four with concomitant IBD had insufficient response.PMID:37716078 | DOI:10.1016/j.jaut.2023.103113
Source: Journal of Autoimmunity - September 16, 2023 Category: Allergy & Immunology Authors: Benedetta Terziroli Beretta-Piccoli Gustav Buescher George Dalekos Kalliopi Zachou Anja Geerts Nasser Semmo Mirjam Kolev Eleonora De Martin Maciej K Janik Jo ão Madaleno Milica Lalosevic Stojkovic J érôme Dumortier Thomas Vanwolleghem Ida Schregel Silj Source Type: research
Analysis of the mechanism of action of Euphorbia fischeriana Steud on cirrhosis based on network pharmacology
This study aimed to employ network pharmacology to elucidate the mechanism by which Euphorbia fischeriana Steud (EFS) exhibits the efficacy on cirrhosis. The compounds and targets of EFS were retrieved from Traditional Chinese Medicine Integrated Database and Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). Next, these compounds and targets were analyzed based on protein-protein interaction (PPI) network. Furthermore, Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling network was established based on KEGG database. We constructed a compound-compound target-intersection target-...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Lu Liu Yinliang Xu Liu Yang Zhenzhong Jiang Xiaoyan Li Source Type: research
Network pharmacology and molecular docking to explore the mechanism of Sheng Xue Bao mixture against iron deficiency anemia
Medicine (Baltimore). 2023 Sep 15;102(37):e35012. doi: 10.1097/MD.0000000000035012.ABSTRACTBased on network pharmacology and molecular docking, we investigated the mechanism of action of Sheng Xue Bao mixture (SXBM) in treating iron deficiency anemia (IDA). We screened the HERB and traditional Chinese medicine systems pharmacology database and analysis platform databases to identify the active ingredients and targets of SXBM. The targets associated with "iron deficiency anemia" were collected from GeneCards, TTD, and OMIM databases. A component-target interaction network was constructed using Cytoscape 3.8.2. The protein-p...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Yun Wang Huang Qinqin Haixia Wang Hongxu Zhang Xinhua Zhang Weiguo Liu Zhenhua Xiang Yuming Gu Source Type: research
Evaluation of the Curative Effect of Treating HBV-related Liver Fibrosis/Cirrhosis Based on the Method of Removing Turbidity and Regulating the Liver
CONCLUSION: Treatment based on removing turbidity and regulating the liver can effectively relieve the clinical symptoms of patients with HBV-related liver fibrosis/cirrhosis, promote the liver function to return to normal, relieve the degree of liver fibrosis, and reduce the LSM value. The curative effect is significant and worthy of clinical application.PMID:37708539
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunzhi Su Zheng Zhi Jinli Zhang Xianxin Meng Fei Su Panpan Zhou Source Type: research
Vaccination coverage survey of children aged 1-3 years in Beijing, China, 2005-2021
CONCLUSION: The coverage level and service quality of routine immunization in Beijing were relatively high. However, as influenced by COVID-19 epidemics, both on-time and in-time vaccination rates decreased significantly, except for BCG and HepB. Under the background of COVID-19 pandemic, the keys to maintain high level of vaccination coverage include flexible immunization service time to ensure the guardians bringing their children for vaccination timely, and more attention from providers to the doses after children's first birthday.PMID:37709591 | DOI:10.1016/j.vaccine.2023.08.015
Source: Vaccine - September 14, 2023 Category: Allergy & Immunology Authors: Wen-Yan Ji Dong-Lei Liu Rui Yu Liang Miao Qian-Li Yuan Luo-Dan Suo Jian-Ping Yu Source Type: research
Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
