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How do new runners maintain their running, and what leads to others stopping? A qualitative, longitudinal study
Psychol Sport Exerc. 2023 Aug 23;70:102515. doi: 10.1016/j.psychsport.2023.102515. Online ahead of print.ABSTRACTMany people who start running do not maintain their behaviour change. We used qualitative, longitudinal methods to explore and interpret the experiences of new runners and answer the question, "What experiences explain how new runners maintain their running or explain why they stop?" We interviewed 20 new runners (all White British, 14 women, 6 men) about their experiences; we interviewed 10 until they stopped running and 10 until they maintained running for 6-12 months (65 interviews in total). We also conducte...
Source: Psychology of Sport and Exercise - September 17, 2023 Category: Sports Medicine Authors: Alister McCormick Pille Pedmanson Ben Jane Paula Watson Source Type: research

Piloting a shared decision-making clinician training intervention in maternity care in Australia: A mixed methods study
CONCLUSION: Shared decision-making training supports maternity clinicians in developing skills that implement woman-centred care in the timing of planned birth.PMID:37717344 | DOI:10.1016/j.midw.2023.103828
Source: Midwifery - September 17, 2023 Category: Midwifery Authors: Teena Clerke Jayne Margetts Helen Donovan Heather L Shepherd Angela Makris Alison Canty Annette Ruhotas Christine Catling Amanda Henry Source Type: research

Quantitative risk assessment of skin sensitising pesticides: Clinical and toxicological considerations
Regul Toxicol Pharmacol. 2023 Sep 15:105493. doi: 10.1016/j.yrtph.2023.105493. Online ahead of print.ABSTRACTLike many other consumer and occupational products, pesticide formulations may contain active ingredients or co-formulants which have the potential to cause skin sensitisation. Currently, there is little evidence they do, but that could just reflect lack of clinical investigation. Consequently, it is necessary to carry out a safety evaluation process, quantifying risks so that they can be properly managed. A workshop on this topic in 2022 discussed how best to undertake quantitative risk assessment (QRA) for pestici...
Source: Regulatory Toxicology and Pharmacology : RTP - September 17, 2023 Category: Toxicology Authors: Olivier Sanvido David A Basketter Aur élie Berthet Denise Bloch Janine Ezendam Nancy B Hopf Nicole Kleinstreuer Leona L Merolla Wolfgang Uter Christiane Wiemann Martin F Wilks Source Type: research

Steroid hormone signaling: What we can learn from insect models
Vitam Horm. 2023;123:525-554. doi: 10.1016/bs.vh.2022.12.006. Epub 2023 Feb 6.ABSTRACTEcdysteroids are a group of steroid hormones in arthropods with pleiotropic functions throughout their life history. Ecdysteroid research in insects has made a significant contribution to our current understanding of steroid hormone signaling in metazoans, but how far can we extrapolate our findings in insects to other systems, such as mammals? In this chapter, we compare steroid hormone signaling in insects and mammals from multiple perspectives and discuss similarities and differences between the two lineages. We also highlight a few un...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Naoki Okamoto Daiki Fujinaga Naoki Yamanaka Source Type: research

How do new runners maintain their running, and what leads to others stopping? A qualitative, longitudinal study
Psychol Sport Exerc. 2023 Aug 23;70:102515. doi: 10.1016/j.psychsport.2023.102515. Online ahead of print.ABSTRACTMany people who start running do not maintain their behaviour change. We used qualitative, longitudinal methods to explore and interpret the experiences of new runners and answer the question, "What experiences explain how new runners maintain their running or explain why they stop?" We interviewed 20 new runners (all White British, 14 women, 6 men) about their experiences; we interviewed 10 until they stopped running and 10 until they maintained running for 6-12 months (65 interviews in total). We also conducte...
Source: Psychology of Sport and Exercise - September 17, 2023 Category: Sports Medicine Authors: Alister McCormick Pille Pedmanson Ben Jane Paula Watson Source Type: research

Medical education empowered by generative artificial intelligence large language models
Trends Mol Med. 2023 Sep 15:S1471-4914(23)00211-3. doi: 10.1016/j.molmed.2023.08.012. Online ahead of print.ABSTRACTGenerative artificial intelligence (GAI) large language models (LLMs), like ChatGPT, have become the world's fastest growing applications. Here, we provide useful strategies for educators in medical and health science (M&HS) to integrate GAI-LLMs into learning and teaching practice, ultimately enhancing students' digital capability.PMID:37718142 | DOI:10.1016/j.molmed.2023.08.012
Source: Trends in Molecular Medicine - September 17, 2023 Category: Molecular Biology Authors: Tanisha Jowsey Jessica Stokes-Parish Rachelle Singleton Michael Todorovic Source Type: research

Quantitative risk assessment of skin sensitising pesticides: Clinical and toxicological considerations
Regul Toxicol Pharmacol. 2023 Sep 15:105493. doi: 10.1016/j.yrtph.2023.105493. Online ahead of print.ABSTRACTLike many other consumer and occupational products, pesticide formulations may contain active ingredients or co-formulants which have the potential to cause skin sensitisation. Currently, there is little evidence they do, but that could just reflect lack of clinical investigation. Consequently, it is necessary to carry out a safety evaluation process, quantifying risks so that they can be properly managed. A workshop on this topic in 2022 discussed how best to undertake quantitative risk assessment (QRA) for pestici...
Source: Regulatory Toxicology and Pharmacology : RTP - September 17, 2023 Category: Toxicology Authors: Olivier Sanvido David A Basketter Aur élie Berthet Denise Bloch Janine Ezendam Nancy B Hopf Nicole Kleinstreuer Leona L Merolla Wolfgang Uter Christiane Wiemann Martin F Wilks Source Type: research

Novel Triangulenes: Computational Investigations of Energy Thresholds for Photocatalytic Water Splitting
Chemphyschem. 2023 Sep 17:e202300556. doi: 10.1002/cphc.202300556. Online ahead of print.ABSTRACTOrganic materials with Inverted Singlet-Triplet (INVEST) gaps are interesting for their potential use as photocatalytic small molecule transformations, like the entirely solar-driven water splitting reaction. However, only few INVEST emitters are thermodynamically able to split water, with first singlet excited states, S1, above 1.27 or 1.76 eV; and absorbing near solar maximum, 2.57 eV. These requirements and the INVEST character are key for achieving long-lived photocatalyst for water splitting. The only known INVEST emitters...
Source: Chemphyschem - September 17, 2023 Category: Chemistry Authors: Kevin Curtis Corban King Samuel O Odoh Source Type: research

Piloting a shared decision-making clinician training intervention in maternity care in Australia: A mixed methods study
CONCLUSION: Shared decision-making training supports maternity clinicians in developing skills that implement woman-centred care in the timing of planned birth.PMID:37717344 | DOI:10.1016/j.midw.2023.103828
Source: Midwifery - September 17, 2023 Category: Midwifery Authors: Teena Clerke Jayne Margetts Helen Donovan Heather L Shepherd Angela Makris Alison Canty Annette Ruhotas Christine Catling Amanda Henry Source Type: research

Steroid hormone signaling: What we can learn from insect models
Vitam Horm. 2023;123:525-554. doi: 10.1016/bs.vh.2022.12.006. Epub 2023 Feb 6.ABSTRACTEcdysteroids are a group of steroid hormones in arthropods with pleiotropic functions throughout their life history. Ecdysteroid research in insects has made a significant contribution to our current understanding of steroid hormone signaling in metazoans, but how far can we extrapolate our findings in insects to other systems, such as mammals? In this chapter, we compare steroid hormone signaling in insects and mammals from multiple perspectives and discuss similarities and differences between the two lineages. We also highlight a few un...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Naoki Okamoto Daiki Fujinaga Naoki Yamanaka Source Type: research

Quantitative risk assessment of skin sensitising pesticides: Clinical and toxicological considerations
Regul Toxicol Pharmacol. 2023 Sep 15;144:105493. doi: 10.1016/j.yrtph.2023.105493. Online ahead of print.ABSTRACTLike many other consumer and occupational products, pesticide formulations may contain active ingredients or co-formulants which have the potential to cause skin sensitisation. Currently, there is little evidence they do, but that could just reflect lack of clinical investigation. Consequently, it is necessary to carry out a safety evaluation process, quantifying risks so that they can be properly managed. A workshop on this topic in 2022 discussed how best to undertake quantitative risk assessment (QRA) for pes...
Source: Regulatory Toxicology and Pharmacology : RTP - September 17, 2023 Category: Toxicology Authors: Olivier Sanvido David A Basketter Aur élie Berthet Denise Bloch Janine Ezendam Nancy B Hopf Nicole Kleinstreuer Leona L Merolla Wolfgang Uter Christiane Wiemann Martin F Wilks Source Type: research

A new paradigm in lignocellulolytic enzyme cocktail optimization: Free from expert-level prior knowledge and experimental datasets
Bioresour Technol. 2023 Sep 15:129758. doi: 10.1016/j.biortech.2023.129758. Online ahead of print.ABSTRACTEffectively pairing diverse lignocellulolytic enzyme cocktails with intricately structured lignocellulosic substrates is an enduring challenge for science and technology. To date, extensive trial-and-error remains the primary approach and no deep-learning methods were developed to address it due to limited experimental data and incomplete expert-level knowledge of enzyme-cocktail-substrate structure-dynamics-function relationships. Here, a novel model is developed to tackle this issue in efficient, cost-effective, and ...
Source: Bioresource Technology - September 17, 2023 Category: Biotechnology Authors: Le Gao Zhuohang Yu Shengjie Wang Yuejie Hou Shouchang Zhang Chichun Zhou Xin Wu Source Type: research

Mercury causes degradation of spatial cognition in a model songbird species
Ecotoxicol Environ Saf. 2023 Sep 15;264:115483. doi: 10.1016/j.ecoenv.2023.115483. Online ahead of print.ABSTRACTMercury is a widespread pollutant of increasing global concern that exhibits a broad range of deleterious effects on organisms, including birds. Because the developing brain is well-known to be particularly vulnerable to the neurotoxic insults of mercury, many studies have focused on developmental effects such as on the embryonic brain and resulting behavioral impairment in adults. It is not well understood how the timing of exposure, for example exclusively in ovo versus throughout life, influences the impact o...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Cara N Brittain Amanda M Bessler Andrew S Elgin Rachel B Layko Sumin Park Shelby E Still Haruka Wada John P Swaddle Daniel A Cristol Source Type: research

Evaluation of a pilot to introduce simulated learning activities to support speech and language therapy students' clinical development
CONCLUSIONS & IMPLICATIONS: Student experience of simulation was positive. One of the key elements students found to support their clinical skills was the importance of the safe space; support for learning instead of correction led them to engage in active learning. Key barriers to simulation related to having sufficient prior knowledge, the skills of the facilitator, group size and the wider learning landscape of the programme. In response to this pilot, there are plans to continue developing this model of simulation and embed simulation across the programme, led by a sound pedagogical approach with clear preparation and ...
Source: International Journal of Language and Communication Disorders - September 16, 2023 Category: Speech-Language Pathology Authors: Emma Ormerod Claire Mitchell Source Type: research