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Cancer: Lymphoma
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Role of non- < em > Helicobacter pylori < /em > gastric Helicobacters in < em > helicobacter pylori < /em > -negative gastric mucosa-associated lymphoid tissue lymphoma
World J Gastroenterol. 2023 Aug 28;29(32):4851-4859. doi: 10.3748/wjg.v29.i32.4851.ABSTRACTMarginal zone lymphomas rank as the third most prevalent form of non-Hodgkin B-cell lymphoma, trailing behind diffuse large B-cell lymphoma and follicular lymphoma. Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a low-grade B-cell neoplasia frequently correlated with Helicobacter pylori (H. pylori)-induced chronic gastritis. On the other hand, a specific subset of individuals diagnosed with GML does not exhibit H. pylori infection. In contrast to its H. pylori-positive counterpart, it was previously believed that H. pylo...
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro K ádima Nayara Teixeira Fabr ício Freire de Melo Source Type: research
The Prognostic and Functional Impact of Sprouty 2 Expression in Non-small Cell Lung Cancer
CONCLUSION: Spry2 expression was lower in tumor tissues than in normal lung parenchyma. Increased expression of Spry2 is associated with poor prognosis. There were no significant associations between epidermal growth factor receptor, anaplastic lymphoma kinase, or c-ros oncogene 1 rearrangement and Spry2 expression. Despite the absence of KRAS mutational analysis, the clinical and epidemiological features of patients suggested that KRAS mutation might be an underlying determinant factor of the functional role of Spry2 in non-small cell lung cancer.PMID:37700432 | DOI:10.1097/COC.0000000000001044
Source: Clinical Lung Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Yusuf Acikgoz Fatma Unal Yildirim Selin Akturk Esen Gokhan Ucar Yakup Ergun Oznur Bal Mutlu Dogan Dogan Uncu Source Type: research
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer
CONCLUSIONS: Our study reveals that USP19 elevates the intracellular Ca2+ concentration to alter ER stress via regulation of BAG6 and BCL2 stability and may be a viable therapeutic target for TNBC therapy.PMID:37700495 | PMC:PMC10497826 | DOI:10.1002/ctm2.1398
Source: Clinical Genitourinary Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Xiaoqiang Zhang Xuyu Chen Fangze Qian Yanhui Zhu Gao He Junzhe Yang Xian Wu Hongfei Zhang Xiafei Yu Xiaoan Liu Source Type: research
Diffuse large B-cell lymphoma of renal origin with hemophagocytic syndrome: a lesson for the clinical nephrologist
J Nephrol. 2023 Sep 13. doi: 10.1007/s40620-023-01763-0. Online ahead of print.NO ABSTRACTPMID:37702915 | DOI:10.1007/s40620-023-01763-0
Source: Journal of Nephrology - September 13, 2023 Category: Urology & Nephrology Authors: Juan Peng Zaizhi Zhu Chao Pu Jin Yuan Zhaodong Shen Source Type: research
Prognostic Markers in the Era of Targeted Therapies
Acta Haematol. 2023 Sep 13. doi: 10.1159/000533704. Online ahead of print.ABSTRACTBackground Small molecules targeting Bruton's tyrosine kinase (BTK) and B-cell lymphoma-2 have become the standard of care for the treatment of chronic lymphocytic leukemia (CLL), replacing chemoimmunotherapy (CIT) in most clinical settings. Ongoing trials explore targeted combinations and minimal residual disease-driven treatment cessation. These dramatic shifts in the current and upcoming treatment landscape of CLL raise the need to reevaluate existing prognostic markers and develop novel ones. Summary This review examines prognostic marker...
Source: Acta Haematologica - September 13, 2023 Category: Hematology Authors: Sorang Kang Inhye E Ahn Source Type: research
Cost of Disease Progression in Diffuse Large B-Cell Lymphoma After Frontline Treatment With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone
CONCLUSION: Treated progression of DLBCL increases adjusted PPPM costs by over $8000 compared with no progression.PMID:37704514 | DOI:10.1016/j.clml.2023.08.005
Source: Clinical Lymphoma and Myeloma - September 13, 2023 Category: Cancer & Oncology Authors: John M Burke Anthony Masaquel Rongrong Wang Farah Hossain Jia Li Summera Qiheng Zhou Carmen D Ng Matthew Matasar Source Type: research
Role of non- < em > Helicobacter pylori < /em > gastric Helicobacters in < em > helicobacter pylori < /em > -negative gastric mucosa-associated lymphoid tissue lymphoma
World J Gastroenterol. 2023 Aug 28;29(32):4851-4859. doi: 10.3748/wjg.v29.i32.4851.ABSTRACTMarginal zone lymphomas rank as the third most prevalent form of non-Hodgkin B-cell lymphoma, trailing behind diffuse large B-cell lymphoma and follicular lymphoma. Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a low-grade B-cell neoplasia frequently correlated with Helicobacter pylori (H. pylori)-induced chronic gastritis. On the other hand, a specific subset of individuals diagnosed with GML does not exhibit H. pylori infection. In contrast to its H. pylori-positive counterpart, it was previously believed that H. pylo...
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro K ádima Nayara Teixeira Fabr ício Freire de Melo Source Type: research
Cost of Disease Progression in Diffuse Large B-Cell Lymphoma After Frontline Treatment With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone
CONCLUSION: Treated progression of DLBCL increases adjusted PPPM costs by over $8000 compared with no progression.PMID:37704514 | DOI:10.1016/j.clml.2023.08.005
Source: Clinical Lymphoma and Myeloma - September 13, 2023 Category: Cancer & Oncology Authors: John M Burke Anthony Masaquel Rongrong Wang Farah Hossain Jia Li Summera Qiheng Zhou Carmen D Ng Matthew Matasar Source Type: research
Role of non- < em > Helicobacter pylori < /em > gastric Helicobacters in < em > helicobacter pylori < /em > -negative gastric mucosa-associated lymphoid tissue lymphoma
World J Gastroenterol. 2023 Aug 28;29(32):4851-4859. doi: 10.3748/wjg.v29.i32.4851.ABSTRACTMarginal zone lymphomas rank as the third most prevalent form of non-Hodgkin B-cell lymphoma, trailing behind diffuse large B-cell lymphoma and follicular lymphoma. Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a low-grade B-cell neoplasia frequently correlated with Helicobacter pylori (H. pylori)-induced chronic gastritis. On the other hand, a specific subset of individuals diagnosed with GML does not exhibit H. pylori infection. In contrast to its H. pylori-positive counterpart, it was previously believed that H. pylo...
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro K ádima Nayara Teixeira Fabr ício Freire de Melo Source Type: research
