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Therapy: Statin Therapy
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Total 723 results found since Jan 2013.
Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study
ConclusionsNight-onset strokes, compared with day-onset strokes, are associated with higher presenting neurologic severity, more frequent END, and worse 3-month functional outcome. These findings suggest that circadian time of onset is an important additional variable for inclusion in epidemiologic natural history studies and in treatment trials of neuroprotective and reperfusion agents for acute ischemic stroke.
Source: PLoS Medicine - February 4, 2022 Category: Internal Medicine Authors: Wi-Sun Ryu Source Type: research
Atherosclerosis: Known and unknown
Pathol Int. 2022 Jan 25. doi: 10.1111/pin.13202. Online ahead of print.ABSTRACTAtherosclerotic disease, such as myocardial infarction and stroke, is the number one killer worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic and environmental factors. In humans, it takes several decades until the clinical complications develop. There are many known risk factors for atherosclerosis, including hypercholesterolemia, hypertension, diabetes and smoking, which are involved in the pathogenesis of atherosclerosis; however, it is generally believed that atherosclerosis is vascular chronic infl...
Source: Atherosclerosis - January 25, 2022 Category: Cardiology Authors: Jianglin Fan Teruo Watanabe Source Type: research
Circulating Metabolome and White Matter Hyperintensities in Females and Males
Conclusions: Circulating metabolomic measures, including multiple lipid measures (e.g., lysophosphatidylcholines, hydroxysphingomyelins, low-density lipoprotein size and composition) and non-lipid metabolites (e.g., hydroxyphenylpyruvate, glucuronate) associate with WMH in a general population of middle-aged and older adults. Some metabolomic measures show marked sex specificities and explain sizable proportion of WMH variance.PMID:35050683 | DOI:10.1161/CIRCULATIONAHA.121.056892
Source: Circulation - January 20, 2022 Category: Cardiology Authors: Eeva Sliz Jean Shin Shahzad Ahmad Dylan M Williams Stefan Frenzel Friederike Gau ß Sarah E Harris Ann-Kristin Henning Maria Del C Valdes Hernandez Yi-Han Hu Beatriz Jim énez Muralidharan Sargurupremraj Carole Sudre Ruiqi Wang Katharina Wittfeld Qiong Ya Source Type: research
Sodium ozagrel and atorvastatin for type 2 diabetes patients with lacunar cerebral infarction
CONCLUSION: Sodium ozagrel with atorvastatin can reduce inflammatory reactions; regulate ESR and HMGB1, PON-1, and MIF levels; control blood glucose and lipid indexes; and alleviate nerve injury without increasing adverse effects of atorvastatin alone.PMID:35047123 | PMC:PMC8696649 | DOI:10.4239/wjd.v12.i12.2096
Source: Atherosclerosis - January 20, 2022 Category: Cardiology Authors: You Yu Lin Wang Xu Zhu Ya-Fei Liu Hai-Ying Ma Source Type: research
Q & A: Dr. Thomas Rando on preventing age-related diseases and turning discoveries into cures
For Dr. Thomas Rando, the path to becoming a physician-scientist began with something that hedidn ’t learn in high school biology.After one class that touched on the connections between neurons and muscle fibers, Rando took it upon to himself to find all the information he could about how cells communicate through electrical signals.Soon, he began pursuing that interest at Harvard University, where he completed his undergraduate work, a doctorate in cell and developmental biology and his medical degree.Rando joined the neurology faculty at the Stanford University School of Medicine in 1995.There, he founded a clinic to t...
Source: UCLA Newsroom: Health Sciences - December 10, 2021 Category: Universities & Medical Training Source Type: news
Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis
Conclusions: Current cigarette smoking, diabetes mellitus, and hypertension are independently associated with incident ASCVD over 16-year follow-up among those with CAC=0. Family history of premature ASCVD may be associated with ASCVD risk among women only.PMID:34879218 | DOI:10.1161/CIRCULATIONAHA.121.056705
Source: Atherosclerosis - December 8, 2021 Category: Cardiology Authors: Mahmoud Al Rifai Michael J Blaha Vijay Nambi Steven J C Shea Erin D Michos Roger S Blumenthal Christie M Ballantyne Moyses Szklo Philip Greenland Michael D Miedema Khurram Nasir Jerome I Rotter Xiuqing Guo Jie Yao Wendy S Post Salim S Virani Source Type: research
Combining ultrasound with bio-indicators reveals progression of carotid stenosis
CONCLUSIONS: High-risk hs-CRP and hypoechoic plaque are independently associated with CAS progression. The progression of carotid stenosis is associated with a high risk of cerebrovascular events.PMID:34872279 | DOI:10.21037/apm-21-2666
Source: Atherosclerosis - December 7, 2021 Category: Cardiology Authors: Mingjian Liu Ziqian Zhang Yan Zhao Zhenghong Chen Bin Chen Yongxu Wei Yijun Cheng Lifeng Zhu Dehua Chen Derong Cui Hanbing Shang Source Type: research
Prevalence of and Factors Associated With the Prescription of Fibrates Among Patients Receiving Lipid-Lowering Drugs in Germany
Abstract:
Little recent data are available about the patterns of prescription for fibrates in patients followed in primary care practices. Therefore, the goal of this study was to analyze the prevalence of and the factors associated with the use of fibrates among patients receiving lipid-lowering drugs in Germany. The study included patients aged ≥18 years with at least 1 visit to 1 of 1070 general practices in Germany between January and December 2019. Lipid-lowering drugs included statins (without and with ezetimibe) and fibrates. The prevalence of the prescription of fibrates corresponded to the number of patients...
Source: Journal of Cardiovascular Pharmacology - December 1, 2021 Category: Cardiology Tags: Original Article Source Type: research
A historical cohort study to investigation of statins safety in COVID-19 hospitalized patients
CONCLUSION: The use of statins did not seem to change outcomes in COVID19.PMID:34776254 | DOI:10.1016/j.therap.2021.10.006
Source: Therapie - November 15, 2021 Category: Psychiatry & Psychology Authors: Saeed Nateghi Mohammad Mahmoudi Gomari Hadiseh Hosamirudsari Behnam Behnoush Asma Razmjoofard Goli Azimi Shokooh Ordookhani Ali Jafarpour Neda Faraji Source Type: research
CCTA plaque data improve heart disease risk assessment in diabetics
Heart plaque data from coronary CT angiography (CCTA) exams boost heart diseas...Read more on AuntMinnie.comRelated Reading:
Are radiologists regaining control of cardiac imaging?
Use AI with CT to better assess stroke patients' collateral flow
Ultrahigh-resolution CT boosts the modality's heart imaging prowess
CTA shows how statin treatment changes coronary plaque
LVO stroke patients benefit from going directly to angiography suite
Source: AuntMinnie.com Headlines - November 1, 2021 Category: Radiology Source Type: news
