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Abstract 10: Predictors of Poor Outcome in Acute Ischemic Stroke Patients after Successful Recanalization Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics
Conclusions: Age, occlusion site, high NIHSS, diabetes, not receiving IV t-PA, use of rescue therapy and three or more passes, were associated with poor 90-day outcome despite successful recanalization.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Starosciak, A. K., Linfante, I., Walker, G., Zaidat, O. O., Castonguay, A. C., Lin, E., Dabus, G., NASA Investigators Tags: Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics Source Type: research

Short-term Changes in Ambient Particulate Matter and Risk of Stroke: A Systematic Review and Meta-analysis Stroke
Conclusions We found that PM2.5 and PM10 are associated with a 1.4% (95% CI 0.9% to 1.9%) and 0.5% (95% CI 0.3% to 0.7%) higher total cerebrovascular disease mortality, respectively, with evidence of inconsistent, nonsignificant associations for hospital admission for total cerebrovascular disease or ischemic or hemorrhagic stroke. Current limited evidence does not suggest an association between PM2.5-10 and cerebrovascular mortality or morbidity. We discuss the potential sources of variability in results across studies, highlight some observations, and identify gaps in literature and make recommendations for future studies.
Source: JAHA:Journal of the American Heart Association - August 7, 2014 Category: Cardiology Authors: Wang, Y., Eliot, M. N., Wellenius, G. A. Tags: Stroke Source Type: research

Association Between In-Hospital Mortality and Renal Dysfunction in 186 219 Patients Hospitalized for Acute Stroke in the Emilia-Romagna Region of Italy
Using a regional Italian database, we evaluated the relationship between renal dysfunction and in-hospital mortality (IHM) in patients with acute stroke (ischemic/hemorrhagic). Patients were classified on the basis of renal damage: without renal dysfunction, with chronic kidney disease (CKD), and with end-stage renal disease (ESRD). Of a total of 186 219 patients with a first episode of stroke, 1626 (0.9%) had CKD and 819 (0.4%) had ESRD. Stroke-related IHM (total cases) was independently associated with CKD, ESRD, atrial fibrillation (AF), age, and Charlson comorbidity index (CCI). In patients with ischemic stroke (n = 15...
Source: Angiology - October 20, 2014 Category: Cardiology Authors: Fabbian, F., Gallerani, M., Pala, M., De Giorgi, A., Salmi, R., Dentali, F., Ageno, W., Manfredini, R. Tags: Stroke Source Type: research

Systolic and Diastolic Blood Pressure Changes in Relation With Myocardial Infarction and Stroke in Patients With Coronary Artery Disease Clinical Trials
In conclusion, in patients with coronary artery disease and initially free from congestive heart failure, a BP reduction from baseline over the examined BP range had little effect on the risk of MI and predicted a lower risk of stroke. An increase in systolic BP from baseline increased the risk of stroke and MI. The relationships of BP with risk were much steeper for stroke than for MI. A treatment-induced BP reduction over the explored range seems to be safe in patients with coronary artery disease. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00153101.
Source: Hypertension - December 10, 2014 Category: Cardiology Authors: Verdecchia, P., Reboldi, G., Angeli, F., Trimarco, B., Mancia, G., Pogue, J., Gao, P., Sleight, P., Teo, K., Yusuf, S. Tags: Secondary prevention, Clinical Studies, Other Stroke Treatment - Medical Clinical Trials Source Type: research

Low blood pressure during the acute period of ischemic stroke is associated with decreased survival
Conclusion: Among patients hospitalized for their first-ever ischemic stroke, the risk of all-cause death is significantly increased in those with admission MBP below 100 mmHg and discharge SBP below 120 mmHg, even after adjustments for other confounders.
Source: Journal of Hypertension - January 6, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Contemporary Trends and Predictors of Postacute Service Use and Routine Discharge Home After Stroke Stroke
Conclusions Four in 10 stroke patients are discharged home without services. Although little has changed overall in PAC use since 2003, further research is needed to explain the shift in service use by type and its effect on outcomes.
Source: JAHA:Journal of the American Heart Association - February 23, 2015 Category: Cardiology Authors: Prvu Bettger, J., McCoy, L., Smith, E. E., Fonarow, G. C., Schwamm, L. H., Peterson, E. D. Tags: Stroke Source Type: research

Abstract 18: Determinants of Adequate Blood Pressure Control in Stroke Patients Post-Discharge Session Title: Concurrent Session IIC: Oral Abstracts - Stroke
Conclusions: Contrary to our hypothesis, once daily dosed BP medications did not improve the effectiveness of BP control at follow-up. Elevated SBP at the time of hospital discharge was associated with poor blood pressure control. Those patients receiving outpatient home health and therapy visits after hospital discharge had better blood pressure control. Further studies need to be done to assess medication adherence to determine whether the poor control was related to choice of medication or patient medication-taking behavior.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Bishop, L., Arnan, M., Petryna, E., Bushnell, C. Tags: Session Title: Concurrent Session IIC: Oral Abstracts - Stroke Source Type: research

Abstract 19: Using the Heckman Selection Model to Assess Selection Bias in Ischemic Stroke Patients with Documented NIHSS Session Title: Concurrent Session IIC: Oral Abstracts - Stroke
Conclusions: We found statistically significant albeit weak selection bias in the documentation of NIHSS in stroke patients. The Heckman Selection Model is a novel method that can be used to assess the presence and magnitude of selection bias when missing data is common.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Thompson, M. P., Luo, Z., Gardiner, J., Burke, J. F., Reeves, M. J. Tags: Session Title: Concurrent Session IIC: Oral Abstracts - Stroke Source Type: research

Abstract 20: Patient Characteristics and Outcomes among Early-Arriving Acute Stroke Patients for Whom Alteplase Was Dispensed but Not Administered Session Title: Concurrent Session IIC: Oral Abstracts - Stroke
Conclusion: Delays in tPA initiation are common, and reduce health outcomes after thrombolysis. In our study, early dispensing of tPA prior to the final eligibility assessment produced an overall rate of tPA treatment of >60%. This conversion rate suggests that early tPA dispensing in high likelihood candidates is appropriate and supports the use of this strategy. Reasons for non-treatment were similar to those in unselected patients.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Siddiqui, K. A., Ali, S. F., Anderson, C. D., Rost, N., Schwamm, L. H. Tags: Session Title: Concurrent Session IIC: Oral Abstracts - Stroke Source Type: research

Novel Oral Anticoagulant Use Among Patients With Atrial Fibrillation Hospitalized With Ischemic Stroke or Transient Ischemic Attack Original Articles
Conclusions— NOACs have had modest but growing uptake over time among atrial fibrillation patients hospitalized with stroke or transient ischemic attack and are prescribed to patients with lower stroke risk compared with warfarin.
Source: Circulation: Cardiovascular Quality and Outcomes - July 21, 2015 Category: Cardiology Authors: Patel, P. A., Zhao, X., Fonarow, G. C., Lytle, B. L., Smith, E. E., Xian, Y., Bhatt, D. L., Peterson, E. D., Schwamm, L. H., Hernandez, A. F. Tags: Other anticoagulants, Embolic stroke, Anticoagulants Original Articles Source Type: research

Mobile Phone-Based Questionnaire for Assessing 3 Months Modified Rankin Score After Acute Stroke: A Pilot Study Original Articles
Conclusions— Mobile phone–based automatic assessments of mRS performed well in comparison with clinical visit mRS and could be used as an alternative in stroke follow-up.
Source: Circulation: Cardiovascular Quality and Outcomes - October 29, 2015 Category: Cardiology Authors: Cooray, C., Matusevicius, M., Wahlgren, N., Ahmed, N. Tags: Ethics and Policy, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Long-Term Stroke Risk Due to Partial White-Coat or Masked Hypertension Based on Home and Ambulatory Blood Pressure Measurements: The Ohasama Study Epidemiology/Population
In conclusion, impacts of partial WCHT as well as partial masked hypertension for long-term stroke risk were comparable to those of complete masked hypertension or sustained hypertension. We need both home and 24-h ambulatory blood pressure measurements to evaluate stroke risk accurately.
Source: Hypertension - December 9, 2015 Category: Cardiology Authors: Satoh, M., Asayama, K., Kikuya, M., Inoue, R., Metoki, H., Hosaka, M., Tsubota-Utsugi, M., Obara, T., Ishiguro, A., Murakami, K., Matsuda, A., Yasui, D., Murakami, T., Mano, N., Imai, Y., Ohkubo, T. Tags: Epidemiology, Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research

Beta-blockers are not associated with stroke severity and outcome in hypertensive patients: data from a national stroke registry
Lowering blood pressure (BP) with beta-blockers is less effective in reducing the risk of stroke than with other agents. However, studies on associations between use of beta-blockers and stroke severity are inconclusive. We assessed the association between pre-stroke use of beta-blockers and stroke severity, disability and death in a large prospective national registry of hospitalized hypertensive patients with acute stroke.
Source: Journal of the American Society of Hypertension - March 31, 2016 Category: Cardiology Authors: Ehud Grossman, David Tanne, Silvia Koton Tags: Stroke Source Type: research

Trends in Acute Ischemic Stroke Hospitalizations in the United States Stroke
Conclusions Although overall stroke hospitalizations declined in the United States, the reduction was more pronounced among older individuals, women, Hispanics, and whites. Renewed efforts at targeting risk factor control among vulnerable individuals may be warranted.
Source: JAHA:Journal of the American Heart Association - May 10, 2016 Category: Cardiology Authors: Ramirez, L., Kim-Tenser, M. A., Sanossian, N., Cen, S., Wen, G., He, S., Mack, W. J., Towfighi, A. Tags: Cardiovascular Disease, Cerebrovascular Disease/Stroke, Ischemic Stroke Source Type: research

Propensity Score-Based Analysis of Percutaneous Closure Versus Medical Therapy in Patients With Cryptogenic Stroke and Patent Foramen Ovale: The IPSYS Registry (Italian Project on Stroke in Young Adults) Structural Heart Disease
Conclusions— PFO closure seems as effective as medical therapy for secondary prevention of cryptogenic ischemic stroke. Whether device treatment might be more effective in selected cases, such as in patients younger than 37 years and in those with a substantial right-to-left shunt size, deserves further investigation.
Source: Circulation: Cardiovascular Interventions - August 30, 2016 Category: Cardiology Authors: Pezzini, A., Grassi, M., Lodigiani, C., Patella, R., Gandolfo, C., Zini, A., DeLodovici, M. L., Paciaroni, M., Del Sette, M., Toriello, A., Musolino, R., Calabro, R. S., Bovi, P., Adami, A., Silvestrelli, G., Sessa, M., Cavallini, A., Marcheselli, S., Mar Tags: Risk Factors, Ischemic Stroke Structural Heart Disease Source Type: research