Propensity Score-Based Analysis of Percutaneous Closure Versus Medical Therapy in Patients With Cryptogenic Stroke and Patent Foramen Ovale: The IPSYS Registry (Italian Project on Stroke in Young Adults) [Structural Heart Disease]

Conclusions—
PFO closure seems as effective as medical therapy for secondary prevention of cryptogenic ischemic stroke. Whether device treatment might be more effective in selected cases, such as in patients younger than 37 years and in those with a substantial right-to-left shunt size, deserves further investigation.

Source: Circulation: Cardiovascular Interventions - August 30, 2016 Category: Cardiology Authors: Pezzini, A., Grassi, M., Lodigiani, C., Patella, R., Gandolfo, C., Zini, A., DeLodovici, M. L., Paciaroni, M., Del Sette, M., Toriello, A., Musolino, R., Calabro, R. S., Bovi, P., Adami, A., Silvestrelli, G., Sessa, M., Cavallini, A., Marcheselli, S., Mar Tags: Risk Factors, Ischemic Stroke Structural Heart Disease Source Type: research