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Parathormone levels add prognostic ability to N ‐terminal pro‐brain natriuretic peptide in stable coronary patients
ConclusionsParathormone is an independent predictor of cardiovascular events in coronary patients, adding complimentary prognostic information to NT ‐proBNP plasma levels. This predictive value is restricted to patients with high FGF23 plasma levels. This should be considered in the design of future studies in this field.
Source: ESC Heart Failure - May 1, 2021 Category: Cardiology Authors: Carlos Guti érrez‐Landaluce, Álvaro Aceña, Ana Pello, Juan Martínez‐Milla, Óscar González‐Lorenzo, Nieves Tarín, Carmen Cristóbal, Luis M. Blanco‐Colio, José Luis Martín‐Ventura, Ana Huelmos, Marta López‐Castillo, Joaquí Tags: Original Research Article Source Type: research

Low vitamin D levels affect left ventricular wall thickness in severe aortic stenosis
Conclusion Among patients with severe degenerative aortic stenosis, vitamin D deficiency is common. We found a significant association between left ventricular wall thickness and vitamin D levels, suggesting a potential role of this hormone in modulating hypertrophic remodelling in these patients. However, future larger studies are certainly needed to confirm our findings and to define their prognostic implications.
Source: Journal of Cardiovascular Medicine - October 6, 2020 Category: Cardiology Tags: Research articles: Valvular heart disease Source Type: research

Vitamin D supplementation, cardiac events and stroke: A systematic review and meta-regression analysis
Publication date: June 2020Source: IJC Heart & Vasculature, Volume 28Author(s): Matthew Nudy, George Krakowski, Mehrdad Ghahramani, Mohammed Ruzieh, Andrew J. Foy
Source: IJC Heart and Vasculature - May 21, 2020 Category: Cardiology Source Type: research

Vitamin D, Marine n-3 Fatty Acids, and Primary Prevention of Cardiovascular Disease Current Evidence.
Abstract Whether marine omega-3 fatty acid (n-3 FA) or vitamin D supplementation can prevent cardiovascular disease (CVD) in general populations at usual risk for this outcome is unknown. A major goal of VITAL (Vitamin D and Omega-3 Trial) was to fill this knowledge gap. In this article, we review the results of VITAL, discuss relevant mechanistic studies regarding n-3 FAs, vitamin D, and vascular disease, and summarize recent meta-analyses of the randomized trial evidence on these agents. VITAL was a nationwide, randomized, placebo-controlled, 2×2 factorial trial of marine n-3 FAs (1 g/d) and vitamin D3 (2000 IU...
Source: Circulation Research - January 2, 2020 Category: Cardiology Authors: Manson JE, Bassuk SS, Cook NR, Lee IM, Mora S, Albert CM, Buring JE, VITAL Research Group Tags: Circ Res Source Type: research

AHA News: Stroke May Lead to Lower Vitamin D
Title: AHA News: Stroke May Lead to Lower Vitamin DCategory: Health NewsCreated: 8/8/2019 12:00:00 AMLast Editorial Review: 8/9/2019 12:00:00 AM
Source: MedicineNet Heart General - August 9, 2019 Category: Cardiology Source Type: news

Vitamin D, Hypertension, and Ischemic Stroke Editorial Commentary
Source: Hypertension - August 9, 2017 Category: Cardiology Authors: Ronen Levi-Vardi, Yoram Yagil Tags: Epidemiology, Genetic, Association Studies, High Blood Pressure, Ischemic Stroke Editorial Commentaries Source Type: research

Vitamin D, Hypertension, and Ischemic Stroke in 116 655 Individuals From the General PopulationNovelty and Significance Epidemiology/Population
Observational studies indicate that low concentrations of plasma 25-hydroxyvitamin D (25(OH)D) are associated with high blood pressure, hypertension, and ischemic stroke. However, whether these associations are causal remain unknown. A total of 116 655 white individuals of Danish descent from the general population were genotyped for genetic variants in DHCR7 and CYP2R1 affecting plasma 25(OH)D concentrations; 35 517 had plasma 25(OH)D measurements. Primary outcomes were blood pressure, hypertension, and ischemic stroke. Median follow-up for incident ischemic stroke was 9.3 years (range, 1 day–33.6 years). DHCR7/CYP2R1 a...
Source: Hypertension - August 9, 2017 Category: Cardiology Authors: Shoaib Afzal, Borge G. Nordestgaard Tags: Risk Factors, Genetic, Association Studies, High Blood Pressure, Hypertension Original Articles Source Type: research

Association between vitamin D deficiency and heart failure risk in the elderly
ConclusionsThere was a high prevalence of vitamin D deficiency in the elderly, and the evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in this population.
Source: ESC Heart Failure - August 1, 2017 Category: Cardiology Authors: Catarina Magalh ães Porto, Vanessa De Lima Silva, João Soares Brito Luz, Brivaldo Markman Filho, Vera Magalhães Silveira Tags: Original Research Article Source Type: research

Associations between calcium and vitamin D supplement use as well as their serum concentrations and subclinical cardiovascular disease phenotypes
Supplementation of calcium (Ca) and vitamin D for the prevention of osteoporosis is frequently found in Western countries. Recent re-analyses of clinical trials observed a higher risk of myocardial infarction and stroke in subjects taking Ca (+vitamin D) supplements, although the underlying mechanisms are not clear.
Source: Atherosclerosis - June 18, 2015 Category: Cardiology Authors: Inke Thiele, Jakob Linseisen, Christa Meisinger, Sigrid Schwab, Cornelia Huth, Annette Peters, Siegfried Perz, Thomas Meitinger, Florian Kronenberg, Claudia Lamina, Joachim Thiery, Wolfgang Koenig, Wolfgang Rathmann, Stefan Kääb, Cornelia Then, Jochen S Source Type: research

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