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Condition: Cholesterol
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Total 18 results found since Jan 2013.
Sex and race define the effects of adverse childhood experiences on self-reported BMI and metabolic health biomarkers
ConclusionsBMI is strongly associated with cumulative ACEs in women regardless the race, while waist circumference is strongly associated with ACEs in Black individuals, which combined with reduced BMI may indicate increased central adiposity in Black men. Our study suggests that sex and race influence the contribution of certain ACEs to impair metabolic health.
Source: Biology of Sex Differences - June 15, 2022 Category: Biology Source Type: research
Association Between Serum Copper and Stroke Risk Factors in Adults: Evidence from the National Health and Nutrition Examination Survey, 2011-2016
This study aimed to examine the relationships between serum copper and lipid levels among 3425 participants aged 20 years and older from the 2011-2016 National Health and Nutrition Examination Survey (NHANES). Data on administered questionnaires, serum copper concentrations, and lipid levels (total cholesterol, HDL cholesterol, triglycerides, and LDL cholesterol) were used. Associations between serum copper and lipid levels were evaluated using both multivariable linear regression and logistic regression models. In the linear regression models, total cholesterol and LDL cholesterol levels increased with increasing copper c...
Source: Biological Trace Element Research - May 6, 2021 Category: Biology Authors: Jingang Xu Guofeng Xu Junkang Fang Source Type: research
The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis
AbstractObesity and elevated serum lipids are associated with a threefold increase in the risk of developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and sudden cardiac death. Strategies that aim to reduce serum cholesterol through modulation of liver enzymes have been successful in decreasing the risk of developing atherosclerosis and reducing mortality. Statins, which inhibit cholesterol biosynthesis in the liver, are considered among the most successful compounds developed for the treatment of cardiovascular disease. However, recent debate surrounding their effectiveness and safety prom...
Source: Biology of Sex Differences - November 26, 2019 Category: Biology Source Type: research
The potential of drug repurposing combined with reperfusion therapy in cerebral ischemic stroke: A supplementary strategy to endovascular thrombectomy
Publication date: Available online 11 October 2019Source: Life SciencesAuthor(s): Jenq-Lin Yang, Yun-Ru Yang, Shang-Der ChenAbstractStroke is the major cause of adult disability and the second or third leading cause of death in developed countries. The treatment options for stroke (thrombolysis or thrombectomy) are restricted to a small subset of patients with acute ischemic stroke because of the limited time for an efficacious response and the strict criteria applied to minimize the risk of cerebral hemorrhage. Attempts to develop new treatments, such as neuroprotectants, for acute ischemic stroke have been costly and tim...
Source: Life Sciences - October 13, 2019 Category: Biology Source Type: research
Statins are more effective for those who follow the Mediterranean diet
(Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S.) For those who have already had a heart attack or a stroke, the combination of statins and Mediterranean Diet appears to be the most effective choice to reduce the risk of mortality, especially from cardiovascular causes. It is the result of an Italian study conducted at the I.R.C.C.S. Neuromed, Pozzilli, Italy on over 1,000 adults recruited in the Moli-sani Study, published in the International Journal of Cardiology.
Source: EurekAlert! - Biology - December 21, 2018 Category: Biology Source Type: news
Differences in discontinuation of statin treatment in women and men with advanced cancer disease
ConclusionStatin treatment was discontinued earlier in women than in men in patients with advanced cancer. The data suggest that statins may be discontinued earlier in men as well, since earlier discontinuation did not affect cardiovascular mortality.
Source: Biology of Sex Differences - October 20, 2018 Category: Biology Source Type: research
Sex differences in outcomes and associated factors among stroke patients with small artery occlusion in China
ConclusionsThese findings suggest that it is crucial to control conventional risk factors and fasting plasma glucose and lipid levels among patients with SAO, especially male patients, to reduce the burden of stroke in China.
Source: Biology of Sex Differences - August 2, 2018 Category: Biology Source Type: research
Assessment of Gender-Related Differences in Vitamin D levels and Cardiovascular Risk factors in Saudi Patients with Type 2 Diabetes Mellitus
Publication date: Available online 4 April 2017 Source:Saudi Journal of Biological Sciences Author(s): Manal Abudawood, Hajera Tabassum, Sabah Ansar, Khalid Almosa, Samia Sobki, Mir Naiman Ali, Ali Aljohi Diabetes is a major risk factor for cardiovascular disease (CVD) including stroke, coronary heart disease, and peripheral artery disease. It remains a leading cause of mortality throughout the world, affecting both women and men. This investigation was aimed to study gender based differences in cardiovascular risk factors of adult population with diabetes mellitus (T2DM) and to check the correlation between serum HbA1C, ...
Source: Saudi Journal of Biological Sciences - April 5, 2017 Category: Biology Source Type: research
Molecular therapy set to protect at-risk patients against heart attack and stroke
(Charit é - Universit ä tsmedizin Berlin) Even a single dose of a specific ribonucleic acid molecule, known as a small interfering RNA (siRNA), offers patients at high risk of cardiovascular disease long-lasting protection against high LDL cholesterol -- one of the main risk factors for heart attack and stroke. This is the result of a clinical study that researchers from Charit é and Imperial College London have published as leading authors in the current edition of New England Journal of Medicine.
Source: EurekAlert! - Biology - March 30, 2017 Category: Biology Source Type: news
Sex differences in outcomes after stroke among patients with low total cholesterol levels: a large hospital-based prospective study
ConclusionsThese findings suggest that patients (both men and women) with atherothrombotic infarction who have low TC levels would not benefit from receiving statin treatment. Therefore, it is crucial to explore the impact of statin treatment on outcomes in Asian patients, especially Chinese patients with atherothrombotic and low TC levels, in order to improve outcomes after stroke and reduce the disease burden.
Source: Biology of Sex Differences - November 23, 2016 Category: Biology Source Type: research
Therapeutic potential of chalcones as cardiovascular agents
Publication date: Available online 11 February 2016 Source:Life Sciences Author(s): Debarshi Kar Mahapatra, Sanjay Kumar Bharti Cardiovascular diseases are the leading cause of death affecting 17.3 million people across the globe and are estimated to affect 23.3 million people by year 2030. In recent years, about 7.3 million people died due to coronary heart disease, 9.4 million deaths due to high blood pressure and 6.2 million due to stroke, where obesity and atherosclerotic progression remain the chief pathological factors. The search for newer and better cardiovascular agents is the foremost need to manage cardiac p...
Source: Life Sciences - February 11, 2016 Category: Biology Source Type: research
TSRI scientists create mimic of 'good' cholesterol to fight heart disease and stroke
(Scripps Research Institute) Scientists at The Scripps Research Institute have created a synthetic molecule that mimics 'good' cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks. The research points scientists toward a new method for treating atherosclerosis, a condition where plaque buildup in the arteries can cause heart attacks and strokes.
Source: EurekAlert! - Biology - October 9, 2014 Category: Biology Source Type: news
Scientists target receptor to treat diabetic retinopathy
(Medical College of Georgia at Georgia Regents University) Like a daily pill to lower cholesterol can reduce heart attack and stroke risk, an easy-to-use agent that reduces eye inflammation could help save the vision of diabetics, scientists say.
Source: EurekAlert! - Biology - April 21, 2014 Category: Biology Source Type: news
