Assessment of Gender-Related Differences in Vitamin D levels and Cardiovascular Risk factors in Saudi Patients with Type 2 Diabetes Mellitus

Publication date: Available online 4 April 2017 Source:Saudi Journal of Biological Sciences Author(s): Manal Abudawood, Hajera Tabassum, Sabah Ansar, Khalid Almosa, Samia Sobki, Mir Naiman Ali, Ali Aljohi Diabetes is a major risk factor for cardiovascular disease (CVD) including stroke, coronary heart disease, and peripheral artery disease. It remains a leading cause of mortality throughout the world, affecting both women and men. This investigation was aimed to study gender based differences in cardiovascular risk factors of adult population with diabetes mellitus (T2DM) and to check the correlation between serum HbA1C, lipid profile and serum vitamin D levels, in T2DM patients of Riyadh, Saudi Arabia. This hospital-based cross-sectional study involving subjects was divided into two gender based groups; normal male (800), diabetic male (800) and normal female (800) and T2DM females (800). Blood samples were analyzed for fasting glucose (FBG), HbA1c, total cholesterol (TC), triglycerides (Tg), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and serum levels of 25(OH)-vitamin D in all groups. All the glycemic control parameters, lipid profile parameters were found significantly different in diabetic vs non-diabetic group (p<0.001) in both genders. The results also show that vitamin D concentration decreased significantly (p<0.001) in diabetic patients than the healthy individuals in both the genders. Vitamin-D an...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research