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Specialty: Cancer & Oncology
Condition: Heart Attack

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Total 138 results found since Jan 2013.

The structured ambulatory post-stroke care program for outpatient aftercare in patients with ischaemic stroke in Germany (SANO): an open-label, cluster-randomised controlled trial
This study was registered with the German Clinical Trials Register, DRKS00015322.FINDINGS: Between Jan 1, 2019 and Dec 22, 2020, 36 clusters were assessed for eligibility, of which 30 were randomly assigned to the intervention group (n=15 clusters) or control group (n=15 clusters). No clusters dropped out of the study. 1203 (86%) of 1396 enrolled patients in the intervention group and 1283 (92%) of 1395 enrolled patients in the control group were included in the mITT population. The primary endpoint was confirmed in 64 (5·3%) of 1203 patients in the intervention group and 80 (6·2%) of 1283 patients in the control group (...
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Christopher J Schwarzbach Felizitas Anna Eichner Viktoria R ücker Anna-Lena Hofmann Moritz Keller Heinrich J Audebert Stephan von Bandemer Stefan T Engelter Dieter Geis Klaus Gr öschel Karl Georg Haeusler Gerhard F Hamann Andreas Meisel Dirk Sander Mart Source Type: research

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis
Hum Reprod Update. 2023 Jun 23:dmad015. doi: 10.1093/humupd/dmad015. Online ahead of print.ABSTRACTBACKGROUND: Current knowledge about the consequences of PCOS during the late reproductive years and after menopause is limited.OBJECTIVE AND RATIONALE: We performed a systematic review and meta-analysis of data on the pathophysiology, clinical manifestations, diagnosis, prognosis, and treatment of women ≥45 years of age-peri- or postmenopausal-with PCOS.SEARCH METHODS: Studies published up to 15 April 2023, identified by Entrez-PubMed, EMBASE, and Scopus online facilities, were considered. We included cross-sectional or pro...
Source: Cancer Control - June 24, 2023 Category: Cancer & Oncology Authors: Mercedes Mill án-de-Meer Manuel Luque-Ram írez L ía Nattero-Chávez H éctor F Escobar-Morreale Source Type: research

Cancers, Vol. 15, Pages 3060: Arterial Thrombosis in Patients with Acute Myeloid Leukemia: Incidence and Risk Factors
Conclusions: Our study showed that patients with AML are at increased risk of ATE. The risk was increased in patients with cardiovascular comorbidities, previous thrombosis, adverse cytogenetic risk as well as BMI > 30.
Source: Cancers - June 5, 2023 Category: Cancer & Oncology Authors: Mirjana Mitrovic Nikola Pantic Nikica Sabljic Zoran Bukumiric Marijana Virijevic Zlatko Pravdic Mirjana Cvetkovic Jovan Rajic Jelena Bodrozic Violeta Milosevic Milena Todorovic-Balint Ana Vidovic Nada Suvajdzic-Vukovic Darko Antic Tags: Article Source Type: research

Influence of chronic diseases on the occurrence of depression: A 13-year follow-up study from the Survey of Health, Ageing and Retirement in Europe
This study aimed to explore the effects of types and number of chronic diseases on the risk of depression using data from the Survey of Health, Ageing and Retirement in Europe (SHARE). A self-admitted questionnaire was used to obtain data on 14 predefined chronic diseases and the European-Depression Scale (EURO-D) was used to assess depression. Among the 16,080 baseline depression-free participants aged 50+, 31.29% (5032) developed depression over 13 years. Multivariate Cox regression models showed that individuals with any chronic diseases were at higher risk of new onset depression compared to disease-free participants. ...
Source: Cancer Control - June 4, 2023 Category: Cancer & Oncology Authors: Meng-Yao Feng Yu-Han Bi Hui-Xin Wang Jin-Jing Pei Source Type: research

Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart
DISCUSSION: While the reported tolerance to ischemic insults in TRAF2 overexpression mice may suggest enhanced cardiac reserve, our results indicate diminished cardiac function in these mice.PMID:37229235 | PMC:PMC10203617 | DOI:10.3389/fcvm.2023.1064640
Source: Cancer Control - May 25, 2023 Category: Cancer & Oncology Authors: Andrea G Marshall Kit Neikirk Zer Vue Heather K Beasley Edgar Garza-Lopez Larry Vang Taylor Barongan Zoe Evans Amber Crabtree Elsie Spencer Josephs Anudokem Remi Parker Jamaine Davis Dominique Stephens Steven Damo Thuy T Pham Jose A Gomez Vernat Exil Dao- Source Type: research

Evidence That Increasing Serum 25(OH)D Concentrations to 30 ng/mL in the Kingdom of Saudi Arabia and the United Arab Emirates Could Greatly Improve Health Outcomes
Biomedicines. 2023 Mar 23;11(4):994. doi: 10.3390/biomedicines11040994.ABSTRACTAccumulating evidence supports the potential protective effects of vitamin D against chronic diseases such as Alzheimer's disease, autoimmune diseases, cancers, cardiovascular disease (ischaemic heart disease and stroke), type 2 diabetes, hypertension, chronic kidney disease, stroke, and infectious diseases such as acute respiratory tract diseases, COVID-19, influenza, and pneumonia, as well as adverse pregnancy outcomes. The respective evidence is based on ecological and observational studies, randomized controlled trials, mechanistic studies, ...
Source: Cancer Control - May 16, 2023 Category: Cancer & Oncology Authors: William B Grant Fatme Al Anouti Barbara J Boucher Hana M A Fakhoury Meis Moukayed Stefan Pilz Nasser M Al-Daghri Source Type: research

The Intersection of Prostate Cancer and Hypertension: a Call to Action
Opinion statementWith improvements in treatment and survival from prostate cancer, comorbid cardiac conditions will significantly impact overall morbidity and mortality from prostate cancer. Hypertension is a well-established cardiovascular risk factor that increases the risk of heart failure, myocardial infarction, and stroke. Therapies used in the treatment of prostate cancer, including GnRH agonists, GnRH antagonists, enzalutamide, abiraterone, and others, can directly or indirectly increase the risk of hypertension. In this paper, we review the evidence available on the incidence and mechanism of hypertension in prosta...
Source: Current Treatment Options in Oncology - May 16, 2023 Category: Cancer & Oncology Source Type: research

Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in  Patients With Solid Cancer
CONCLUSIONS: In a large genomic tumor-profiling registry of patients with solid cancers, alterations in KRAS and STK11 were associated with an increased risk for ATE independent of cancer type. Further investigation is needed to elucidate the mechanism by which these mutations contribute to ATE in this high-risk population.PMID:37144118 | PMC:PMC10152200 | DOI:10.1016/j.jaccao.2023.01.009
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Stephanie Feldman Dipti Gupta Babak B Navi Ka-Wai Grace Ho Peter Willeit Sean Devlin Kelly L Bolton Maria E Arcila Simon Mantha Source Type: research

Cancers, Vol. 15, Pages 2316: Review of Cardiovascular Risk of Androgen Deprivation Therapy and the Influence of Race in Men with Prostate Cancer
K. Kelly Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke. This review summarizes the available research on the cardiovascular risk of men using androgen deprivation therapy. We also discuss racial disparities surrounding both prostate cancer and cardiovascular disease, emphasizing the importance of biological/molecular and socioeconomic factors in assessing baseline risk in patients beginning androgen ablation. Based on the literature, ...
Source: Cancers - April 15, 2023 Category: Cancer & Oncology Authors: James Fradin Felix J. Kim Grace L. Lu-Yao Eugene Storozynsky William K. Kelly Tags: Review Source Type: research

Long-term Cardiovascular Risks of Gonadotropin-releasing Hormone Agonists and Antagonists: A Population-based Cohort Study
CONCLUSIONS: GnRH antagonists may be associated with higher long-term, but not short-term, cardiovascular risks than agonists in Asian patients with PCa, particularly in those without known cardiovascular risk factors.PMID:37031076 | DOI:10.1016/j.clon.2023.03.014
Source: Clinical Prostate Cancer - April 8, 2023 Category: Cancer & Oncology Authors: J S K Chan Y H A Lee J M H Hui K Liu E C Dee K Ng P Tang G Tse C F Ng Source Type: research

Arterial and Venous Thromboembolism in ALK-Rearrangement-Positive Non-small Cell Lung Cancer: A Population-Based Cohort Study
CONCLUSIONS: In this study, we observed a higher VTE risk, but not ATE risk, in patients with ALK-rearranged NSCLC relative to those without ALK rearrangement. Prospective studies are warranted to evaluate thromboprophylaxis in ALK-positive NSCLC.PMID:37014824 | DOI:10.1093/oncolo/oyad061
Source: The Oncologist - April 4, 2023 Category: Cancer & Oncology Authors: Oded Icht Avi Leader Erez Batat Lilach Yosef Tzippy Shochat Daniel A Goldstein Elizabeth Dudnik Galia Spectre Pia Raanani Ariel Hammerman Alona Zer Source Type: research