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Ischemic Stroke Due to Heparin-induced Thrombocytopenia During Severe COVID-19 Infection
Intern Med. 2022 Jul 5. doi: 10.2169/internalmedicine.9531-22. Online ahead of print.ABSTRACTA 53-year-old woman with severe coronavirus disease 2019 (COVID-19) pneumonia was admitted and treated with intravenous unfractionated heparin for thromboprophylaxis under general anesthesia with mechanical ventilation. She developed right hemiparesis after hospitalization due to a large hemorrhagic infarction. Her platelet count decreased from 243,000/μL at administration to 121,000/μL. Anti-platelet factor 4-heparin antibody testing was positive according to a latex immunoturbidimetric assay. She was therefore diagnosed with he...
Source: Internal Medicine - July 6, 2022 Category: Internal Medicine Authors: Yasutaka Murakami Shuhei Okazaki Makoto Yamamoto Rei Sakurai Jyunki Jinno Tatsuhiko Ozono Kensuke Ikenaka Yasufumi Gon Kenichi Todo Tsutomu Sasaki Haruhiko Hirata Akinori Uchiyama Hideki Mochizuki Source Type: research

Functional outcomes of COVID-19 patients with acute ischemic stroke: A prospective, observational, single-center study in North Jordan
We assessed whether stroke severity, functional outcome, and mortality in patients with ischemic stroke differed between patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and those without.
Source: Medicine - July 1, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Effects of statins on the risks of ischemic stroke and heart disease in human immunodeficiency virus infection, influenza and severe acute respiratory syndrome-associated coronavirus: respiratory virus infection with steroid use
CONCLUSION: Statin use was associated with lower aHRs for ischemic stroke and heart disease in those with HIS disorders with comorbidities.PMID:35590450 | DOI:10.1080/00325481.2022.2080359
Source: Postgraduate Medicine - May 20, 2022 Category: Internal Medicine Authors: Jun-Jun Yeh Meichu Lai Cheng-Li Lin Kuan-Hua Lu Chia-Hung Kao Source Type: research

The impact of COVID-19 on home, social, and productivity integration of people with chronic traumatic brain injury or stroke living in the community
Compare community integration of people with stroke or traumatic brain injury (TBI) living in the community before and during the coronavirus severe acute respiratory syndrome coronavirus 2 disease (COVID-19) when stratifying by injury: participants with stroke (G1) and with TBI (G2); by functional independence in activities of daily living: independent (G3) and dependent (G4); by age: participants younger than 54 (G5) and older than 54 (G6); and by gender: female (G7) and male (G8) participants. Prospective observational cohort study In-person follow-up visits (before COVID-19 outbreak) to a rehabilitation hospital ...
Source: Medicine - February 25, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Cerebral venous sinus thrombosis as a complication of COVID-19 infection - A case report
CONCLUSION: High index of suspicion of CVST is necessary when a patient presents with unexplained neurological manifestation following a recent COVID-19 infection to prevent from life-threatening complications. Furthermore, clinicians should not underestimate the multisystem involvement of COVID-19.PMID:35127077 | PMC:PMC8800506 | DOI:10.1016/j.amsu.2022.103326
Source: Annals of Medicine - February 7, 2022 Category: Internal Medicine Authors: Suyasha Rajbhandari Saujanya Rajbhandari Avinash Chandra Pritam Gurung Pravesh Rajbhandari Basant Pant Source Type: research

Effect of the COVID-19 pandemic in stroke code activations in the region of Madrid: A retrospective study
Acute sstroke is the most common time-dependent disease attended in the emergency medical service (EMS) of Madrid (SUMMA 112). Community of Madrid has been one of the most affected regions in Spain by the coronavirus disease 2019 (COVID-19) pandemic. A significant reduction in acute sstroke hospital admissions has been reported during the COVID-19 pandemic compared to the same period 1 year before. As international clinical practice guidelines support those patients with suspected acute stroke should be accessed via EMS, it is important to know whether the pandemic has jeopardized urgent pre-hospital stroke care, the first...
Source: Medicine - October 29, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Thromboembolic Risk in Hospitalized and Nonhospitalized COVID-19 Patients
To assess the associations between coronavirus disease 2019 (COVID-19) infection and thromboembolism including myocardial infarction (MI), ischemic stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE).
Source: Mayo Clinic Proceedings - July 15, 2021 Category: Internal Medicine Authors: Frederick K. Ho, Kenneth K.C. Man, Mark Toshner, Colin Church, Carlos Celis-Morales, Ian C.K. Wong, Colin Berry, Naveed Sattar, Jill P. Pell Tags: Original article Source Type: research

Effects of hypertension on the outcomes of COVID-19: a multicentre retrospective cohort study
Conclusion: Hypertension does not affect the outcome of COVID-19, which is different than the conclusions drawn in other studies. However, the 28-day mortality and total 60-day mortality rates of hypertensive patients (age ≥ 70) with COVID-19 were significantly elevated, and compared with the group of survivors, non-surviving COVID-19 patients with hypertension were older, had more basic diseases and had a more severe clinical condition.PMID:34080499 | DOI:10.1080/07853890.2021.1931957
Source: Annals of Medicine - June 3, 2021 Category: Internal Medicine Authors: Li Zhong Yuting Wu Jinghua Gao Jinxia Zhang Qifeng Xie Huang He Jingjing Ji Zheying Liu Conglin Wang Zhifeng Liu Source Type: research

Simultaneous cardio-cerebral infarction in the coronavirus disease pandemic era: A case series
Conclusion: Early recognition and immediate treatment is important in different scenarios leading to thrombosis as the outcome. Additionally, addressing the unknown risks that could contribute to our traditional understanding of these causative mechanisms is important. The hypothesis of exacerbated damage caused by inflammatory and immunological endothelial systemic damage should further be explored to be able to delineate new possibilities in managing these conditions.
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Deferral of Care for Serious Non –COVID-19 Conditions
The harms of the coronavirus disease 2019 (COVID-19) pandemic have been innumerable, including illness, death and disability, unemployment and devastation of small businesses, hunger, educational losses, and amplification of racial and social inequities. In this issue of JAMA Internal Medicine, 2 articles shed light on another cost: deferral of care for serious non –COVID-19 conditions, such as myocardial infarction and stroke.
Source: JAMA Internal Medicine - October 26, 2020 Category: Internal Medicine Source Type: research

Telestroke in the Time of COVID-19: The Mayo Clinic Experience
On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) a pandemic, and in the weeks following, public health organizations, medical associations, and governing bodies throughout the world recommended limiting contact with others to “flatten the curve” of COVID-19. Although both ischemic and hemorrhagic strokes have been reported with COVID-19, there has been anecdotal suggestion of an overall decrease in stroke admissions. To date, the effects of any pandemic on telestroke service lines have not been described.
Source: Mayo Clinic Proceedings - June 12, 2020 Category: Internal Medicine Authors: Josephine F. Huang, Melanie R.F. Greenway, Deena M. Nasr, Felix E. Chukwudelunzu, Bart M. Demaerschalk, Cumara B. O ’Carroll, Charisse A. Nord, Emily A. Pahl, Kevin M. Barrett, Lindsy N. Williams Tags: Brief Report Source Type: research

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