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Specialty: International Medicine & Public Health
Drug: Aspirin
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Total 37 results found since Jan 2013.
Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania
ConclusionsThe 90-day mortality of stroke presenting at MNH is 50%, much higher than in higher income settings. Although severe stroke presentations are a major factor, efforts to improve the quality of care and prevent complications of stroke are urgently needed. Acute stroke interventions with low number needed to treat represent challenging long-term goals.
Source: International Journal for Quality in Health Care - August 28, 2018 Category: International Medicine & Public Health Source Type: research
PCV22 Estimating the Reduction in Medical Care Costs Associated with Ticagrelor and Aspirin in Patients with Acute Ischemic Stroke or TIA
The efficacy of ticagrelor 90mg and aspirin (ticagrelor-aspirin) for the prevention of stroke following an ischaemic stroke (IS) or transient ischaemic attack (TIA) was evaluated in the Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death (THALES, NCT03354429) trial. Ticagrelor-aspirin resulted in a 17% reduction in the risk of stroke or death over 30 days versus aspirin, but with more bleeding events. Ticagrelor 90mg is approved to reduce stroke risk in patients with acute IS (NIH Stroke Scale score ≤5) or high-risk TIA by the Food and Drug Administration.
Source: Value in Health - June 1, 2021 Category: International Medicine & Public Health Authors: P. McEwan, O. Darlington, M. Knutsson, H. Denison, P. Ladenvall, P. Amarenco, S.C. Johnston, S. Evans, S. James, A. Himmelmann, J. Venditto, C. Mellstrom, N. Atreja, A. Tank Source Type: research
Risk factors of hemorrhagic and ischemic stroke among hospitalized patients in Bangladesh - A case control study
The risk factor profiles, management and outcome have significant difference between stroke subsets. Aim of this study was to investigate the risk for the two most common subtypes of stroke in Bangladeshi population. Seventy cases of hemorrhagic stroke (HS) and 105 cases of confirmed ischemic stroke (IS) were recruited from the Shaheed Suhrawardy Medical College Hospital (ShSMCH) and Dhaka Medical College Hospital between January-June 2011. Total 171 age, sex matched controls were selected from the hospitalized patients with history of no stroke ever. Average hemorrhagic stroke patients (60.4 ±12.3 years) were younger tha...
Source: Bangladesh Medical Research Council Bulletin - November 3, 2016 Category: Global & Universal Source Type: research
Use of aspirin and statins for the primary prevention of myocardial infarction and stroke in patients with human immunodeficiency virus infection
This retrospective, cross-sectional study evaluated whether HIV-infected patients received aspirin and statins for the primary prevention of myocardial infarction and stroke. Among the 258 patients included, 50.4% (n = 130/258) of the patients had a high risk of myocardial infarction and 14% (n = 36/258) of stroke. Overall, 43.1% (n = 56/130) and 50% (n = 18/36) of the patients were prescribed aspirin for the primary prevention of myocardial infarction and stroke, respectively. Among the patients who required statin therapy, 42.5% (n = 34/80) and 37.1% (n = 13/35) of patients received it for the primary prevention of myoca...
Source: International Journal of STD and AIDS - April 6, 2016 Category: Global & Universal Authors: Park, T. E., Yusuff, J., Sharma, R. Tags: Original research articles Source Type: research
Study On Drug Utilization And Assessment Of Stroke Risk Using Chads2 And Cha2ds2-Vasc Scoring In Elderly Patients With Non-Valvular Atrial Fibrillation
Stroke Risk Stratification in AF patients of can be done using CHADS2 (Congestive heart failure, Hypertension, Age ≥75, DM, prior Stroke/TIA [2 points] ); or CHA2DS2VASc2 (Congestive heart failure/left ventricular ejection fraction ≤35%, Hypertension, Age ≥75 [2 points], DM, prior Stroke/TIA/thromboembolism [2 points], Vascular disease, Age 65–74, Sex- female). Treatment options for Prevention of stroke includes Anti-coagulants (Vitamin K Antagonist-Warfarin, Acenocoumarol; and Newer Oral Anticoagulant- Dabigatran) and anti-platelets (Aspirin and Clopidogrel).
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: T. Raj, S. Bonthu, S.R. Mallayasamy Source Type: research
International study suggests combination therapy may prevent stroke in certain people
(NIH/National Institute of Neurological Disorders and Stroke) Results from an international clinical trial of more than 4880 participants, published in the New England Journal of Medicine, show that combining clopidogrel and aspirin following a small stroke or experiencing minor stroke symptoms decreases risk of a new stroke, heart attack or other ischemic event within 90 days. The combination therapy was also associated with an increase in major bleeding, although many of those episodes were non-fatal and did not occur in the brain.
Source: EurekAlert! - Medicine and Health - May 17, 2018 Category: International Medicine & Public Health Source Type: news
Optimal Choice of Pharmacological Therapy – Prevention of Stroke and Assessment of Bleeding Risk in Patients with Atrial Fibrillation
Conclusions:Novel oral anticoagulants (NOACs) seem to be a better choice as a pharmacological therapy in the treatment of AF, due to a lack of adequate monitoring of patients ’ international normalized ratio (INR) values. CHA2DS2‑VASc and HASBLED scores must be used as a part of routine clinical diagnostics when dealing with patients with AF.Keywords:Atrial fbrillation, hemorrhage, risk, stroke, therapeutics
Source: International Journal of Preventive Medicine - June 3, 2019 Category: International Medicine & Public Health Source Type: research
Newer blood thinner plus aspirin reduced stroke risk by 27% in patients with heart plaque
(American Heart Association) Patients who suffered a 'warning stroke' were less likely to have another stroke or die within 30 days if treated with a combination of aspirin and a newer blood thinner, ticagrelor. Researchers say that for patients with minor stroke treated within 24 hours of symptom onset, clinicians should consider the combination of ticagrelor plus aspirin to prevent a subsequent stroke.
Source: EurekAlert! - Medicine and Health - November 17, 2020 Category: International Medicine & Public Health Source Type: news
EE165 Cost-Effectiveness Analysis Model of Aspirin and Aspirin Combination Therapy in Acute Ischemic Stroke Patient in West Sumatera
Aspirin usage as monotherapy in acute ischemic stroke has been well-documented as the therapeutic option for early stroke management and recurrent stroke prevention. Recent studies have shown the potential of aspirin combination (dual antiplatelet therapy with clopidogrel) in effectively decreasing the possibility of recurrent stroke. Despite the promising clinical effectiveness, a cost-effectiveness model was built to compare these two options.
Source: Value in Health - June 26, 2022 Category: International Medicine & Public Health Authors: N Fitria, F Putrizeti, YO Sari Source Type: research
Cost–Effectiveness of Clopidogrel-Aspirin Versus Aspirin Alone for Acute Tia and Minor Stroke
This study sought to estimate the cost-effectiveness of clopidogrel-aspirin regimen for acute TIA or minor stroke.
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: Y. Pan, Y.L. Wang, G. Liu, K. Zhao, Y. Wang Source Type: research
Stroke prevention drug combo shows promise, study says
(University of Texas at Austin) If you've had a minor stroke or a transient ischemic stroke (TIA), taking the clot-preventing drug clopidogrel along with aspirin may lower your risk of having a major stroke within the next 90 days, according to new research published in The New England Journal of Medicine.
Source: EurekAlert! - Medicine and Health - May 16, 2018 Category: International Medicine & Public Health Source Type: news
Aspirin Versus Clopidogrel in Patients with Ischemic Stroke: a Cost and Effectiveness Comparison from Beijing Medical Insurance Database
To compare the cost and effectiveness of aspirin and clopidogrel in ischemic stroke(IS) patients from data of Beijing medical insurance database.
Source: Value in Health - October 23, 2015 Category: Global & Universal Authors: L Wen, J Wu, L Yang Source Type: research
Aspirin Versus Clopidogrel in Prevention of Ischemic Stroke Recurrence: An Evaluation of Effectiveness and Safety from Beijing Medical Insurance Database
To evaluate the effectiveness and safety of aspirin and clopidrogel in prevention of ischemic stroke (IS) recurrence from data of Beijing medical insurance database.
Source: Value in Health - April 30, 2016 Category: Global & Universal Authors: L Yang, L Wen, J Wu Source Type: research
Aspirin may lower stroke risk in women with history of preeclampsia
(Columbia University Irving Medical Center) A new study by Columbia researchers suggests aspirin may lower stroke risk among middle-aged women with a history of preeclampsia.
Source: EurekAlert! - Medicine and Health - January 22, 2019 Category: International Medicine & Public Health Source Type: news
Oral anticoagulants: a systematic overview of reviews on efficacy and safety, genotyping, self-monitoring, and stakeholder experiences
ConclusionsFor stroke prevention in AF, direct OACs seem to be more effective and safer than usual care, and apixaban (5 mg twice daily) had the best profile. For VTE, there was no strong evidence that direct OACs were better than usual care. Education and pharmacist management could improve coagulation control. Both clinicians and patients rated efficacy and safety as the most important factors in managing AF and V TE.Systematic review registrationPROSPERO CRD42017084263 —one deviation; efficacy and safety were from one review.
Source: Systematic Reviews - October 28, 2022 Category: International Medicine & Public Health Source Type: research
