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Relationships between environmental factors and participation in adults with traumatic brain injury, stroke, and spinal cord injury: a cross-sectional multi-center study - Wong AWK, Ng S, Dashner J, Baum MC, Hammel J, Magasi S, Lai JS, Carlozzi NE, Tulsky DS, Miskovic A, Goldsmith A, Heinemann AW.
PURPOSE: To develop and evaluate a model of environmental factors-participation relationships for persons with traumatic brain injury (TBI), stroke, and spinal cord injury (SCI), and test whether this model differed across three diagnostic groups, as well ...
Source: SafetyLit - May 2, 2017 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Loyola developing new treatment for stroke and spinal cord injury
(Loyola University Health System) Loyola Medicine has launched a research program to study a new treatment approach for stroke and spinal cord injury patients that involves electrically stimulating nerves. The goal is to improve a patient's ability to function and to develop a relatively inexpensive treatment that could be adapted worldwide.
Source: EurekAlert! - Medicine and Health - October 5, 2018 Category: International Medicine & Public Health Source Type: news

Cognitive, emotional, and physical functioning as predictors of paid employment in people with stroke, traumatic brain injury, and spinal cord injury - Wong AWK, Chen C, Baum MC, Heaton RK, Goodman B, Heinemann AW.
OBJECTIVE: Our objective was to examine demographic, cognitive, emotional, and physical factors that predict return to paid employment for people after neurological injury. METHOD: Four hundred eighty adults with stroke (n = 149), traumatic brain i...
Source: SafetyLit - March 29, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Stroke drug boosts stem cell therapy for spinal cord injury in rats
(University of California - San Diego) In a UC San Diego study, rats with spinal cord injuries experienced a three-fold increase in motor activity when treated with neural progenitor cells that had been pre-conditioned with a modified form of tPA, a drug commonly used to treat non-hemorrhagic stroke.
Source: EurekAlert! - Medicine and Health - December 17, 2019 Category: International Medicine & Public Health Source Type: news

New dimensions in the treatment of muscle spasticity after stroke and nervous system defects
(E ö tv ö s Lor á nd University (ELTE), Faculty of Science) Chronic muscle spasticity after nervous system defects like stroke, traumatic brain and spinal cord injury, multiple sclerosis and painful low back pain affect more than 10% of the population, with a socioeconomic cost of about 500 billion USD. Currently, there is no satisfying remedy to help these suffering people, which generates an immense medical need for a new generation antispastic drug. Drug candidate MPH-220 could mean new hope for millions of patients suffering from spasticity.
Source: EurekAlert! - Medicine and Health - October 16, 2020 Category: International Medicine & Public Health Source Type: news

Feasibility study of problem-solving training for care partners of adults with traumatic brain injury, spinal cord injury, burn injury, or stroke during the inpatient hospital stay - Juengst SB, Osborne CL, Holavanahalli R, Silva V, Kew CL, Nabasny A, Bell KR.
OBJECTIVE: To determine the feasibility of delivering an evidence-based self-management intervention, problem-solving training (PST), to care partners of individuals with traumatic brain injury (TBI), spinal cord injury (SCI), burn injury, or stroke during...
Source: SafetyLit - February 8, 2021 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Engaging Individuals with Neurological Conditions and Caregivers in Rural Communities in a Health Research Team.
CONCLUSIONS: It is imperative to involve those living with a diagnosis or in an under-resourced community to develop the solutions that will work for them in their settings. PMID: 31178448 [PubMed - in process]
Source: Progress in Community Health Partnerships - June 11, 2019 Category: International Medicine & Public Health Tags: Prog Community Health Partnersh Source Type: research

POSB90 Healthcare Resource Utilization and Costs in Adult Patients with Spasticity: A Matched Cohort Analysis
Spasticity is abnormal muscle tightness due to muscle contraction associated with damage to the brain, spinal cord, or motor nerves, and is seen in individuals with neurological etiologies such as cerebral palsy (CP), multiple sclerosis (MS), stroke, or injuries to the central nervous system (CNS). Spasticity affects more than 12 million individuals worldwide. This analysis evaluated incremental healthcare resource utilization (HCRU) and costs in adult patients with spasticity and either CP, MS, stroke, or CNS injury (cases) versus a random sample of patients without spasticity (controls) over a 1-year period from a U.S.
Source: Value in Health - January 1, 2022 Category: International Medicine & Public Health Authors: M Hull, VR Anupindi, J He, N Danchenko, M DeKoven, J Bouchard Source Type: research

Health-related quality of life and economic impact of urinary incontinence due to detrusor overactivity associated with a neurologic condition: a systematic review
Conclusions: Incontinent patients with underlying neurologic conditions have impaired HRQoL as well as substantial economic burden attributable to UI due to NDO. There is a need for urgency UI treatments that improve HRQoL of these patients and alleviate the economic burden of this condition.
Source: Health and Quality of Life Outcomes - January 31, 2013 Category: Global & Universal Authors: Crisanta TapiaKristin KhalafKarina BerensonDenise GlobeMichael ChancellorLesley Carr Source Type: research

Reflex control could improve walking after incomplete spinal injuries
(NIH/National Institute of Neurological Disorders and Stroke) A training regimen to adjust the body's motor reflexes may help improve mobility for some people with incomplete spinal cord injuries, according to a study supported by the National Institutes of Health.
Source: EurekAlert! - Social and Behavioral Science - February 5, 2013 Category: Global & Universal Source Type: news

FDA clears medical device for muscle and joint rehabilitation
(Oregon Health & Science University) The Food and Drug Administration today granted 510(k) clearance to a muscle and joint rehabilitation medical device developed by OHSU Scientist Dr. Paul Cordo, Ph.D., and AMES Technology, Inc. Patients who might use the device include stroke victims and patients with partial injuries to the spinal cord injury patients.
Source: EurekAlert! - Social and Behavioral Science - May 30, 2013 Category: Global & Universal Source Type: news

A quality assessment of systematic reviews on telerehabilitation: what does the evidence tell us?
CONCLUSIONS: In the authors' knowledge this is the first attempt to evaluate the quality of systematic reviews on telerehabilitation. This work also identified the main findings related to the high-scored systematic reviews; the analysis confirms that there is a mounting evidence concerning the effectiveness of telerehabilitation, at least for some pathologies. PMID: 25857379 [PubMed - in process]
Source: Annali dell'Istituto Superiore di Sanita - January 1, 2015 Category: Global & Universal Authors: Rogante M, Kairy D, Giacomozzi C, Grigioni M Tags: Ann Ist Super Sanita Source Type: research

Study finds major lack of resources for rehab patients in Malawi
(University of Maryland School of Medicine) Malawi has a population of 16 million, yet, only one inpatient rehabilitation center for individuals with stroke, spinal cord injury, and similar conditions. Leslie B. Glickman, a researcher at the University of Maryland School of Medicine, examined how patients reintegrated into their community after leaving. She found that patients had moderate to severe difficulties.
Source: EurekAlert! - Medicine and Health - August 25, 2015 Category: Global & Universal Source Type: news

New role identified for scars at the site of injured spinal cord
(NIH/National Institute of Neurological Disorders and Stroke) For decades, it was thought that scar-forming cells called astrocytes were responsible for blocking neuronal regrowth across the level of spinal cord injury, but recent findings challenge this idea. According to a new mouse study, astrocyte scars may actually be required for repair and regrowth following spinal cord injury. The research was funded by the National Institutes of Health, and published in Nature.
Source: EurekAlert! - Medicine and Health - April 7, 2016 Category: Global & Universal Source Type: news

Molecule shown to repair damaged axons
(McGill University) A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.
Source: EurekAlert! - Medicine and Health - March 8, 2017 Category: Global & Universal Source Type: news

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