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Specialty: Pediatrics
Source: Pediatric Research

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Total 48 results found since Jan 2013.

Family reflections: our family journey after a stroke at 16
Pediatr Res. 2023 Apr 15. doi: 10.1038/s41390-023-02602-5. Online ahead of print.NO ABSTRACTPMID:37061643 | DOI:10.1038/s41390-023-02602-5
Source: Pediatric Research - April 15, 2023 Category: Pediatrics Authors: Roz Weeks Source Type: research

Family reflections: discovering the power of integrative therapies for pediatric stroke
Pediatr Res. 2023 Feb 24. doi: 10.1038/s41390-023-02530-4. Online ahead of print.NO ABSTRACTPMID:36828970 | DOI:10.1038/s41390-023-02530-4
Source: Pediatric Research - February 24, 2023 Category: Pediatrics Authors: Camie Rodan Source Type: research

Brain-derived neurotrophic factor and neuroimaging in pediatric patients with sickle cell disease
CONCLUSION: Serum BDNF levels were higher in sickle disease patients who had abnormal transcranial Doppler. BDNF had a significant diagnostic ability in the detection of SCD complications.IMPACT: Silent stroke is a very serious complication in children with sickle cell disease, so regular follow up should be every six months. BDNF is considered a potential biomarker for stroke risk prediction in patients unable to receive TCD.PMID:36774398 | DOI:10.1038/s41390-023-02513-5
Source: Pediatric Research - February 11, 2023 Category: Pediatrics Authors: Asmaa A Mahmoud Sameh A Abd El Naby Ahmed S Abdelgawad Marwa Sabry Rizq Nahla M S Abd El Hady Source Type: research

Early predictors of neurodevelopment after perinatal arterial ischemic stroke: a systematic review and meta-analysis
CONCLUSION: Corticospinal tract assessment on MRI and standardized motor assessments are best to predict cerebral palsy after PAIS. Future research should be focused on improving outcome prediction for non-motor outcomes.IMPACT: We present a systematic review of early predictors for various long-term outcome categories after perinatal arterial ischemic stroke (PAIS), including a meta-analysis for the outcome unilateral spastic cerebral palsy. Corticospinal tract assessment on MRI and standardized motor assessments are best to predict cerebral palsy after PAIS, while bedside techniques such as (a)EEG and NIRS might improve ...
Source: Pediatric Research - December 27, 2022 Category: Pediatrics Authors: Lisanne M Baak Niek E van der Aa Annemijn A E Verhagen Jeroen Dudink Floris Groenendaal Cora H A Nijboer Manon J N L Benders Nienke Wagenaar Source Type: research

Cardiovascular outcomes in children with Kawasaki disease: a population-based cohort study
CONCLUSION: KD survivors are at increased risk of post-discharge cardiovascular events but have a lower risk of death, which justifies enhanced cardiovascular disease surveillance in these patients.IMPACT: Among 4597 Kawasaki disease (KD) survivors, 79 (1.7%) experienced major adverse cardiac events (MACE) and 632 (13.8%) had composite cardiovascular events during 11-year median follow-up. KD survivors had significantly higher risks of post-discharge MACE and cardiovascular events versus non-exposed children. Only nine KD survivors (0.2%) died during follow-up, and the risk of mortality was significantly lower among KD sur...
Source: Pediatric Research - November 15, 2022 Category: Pediatrics Authors: Cal Robinson Rahul Chanchlani Anastasia Gayowsky Sandeep Brar Elizabeth Darling Catherine Demers Tapas Mondal Rulan Parekh Hsien Seow Michelle Batthish Source Type: research

Mesenchymal stem cell therapy in perinatal arterial ischemic stroke: systematic review of preclinical studies
CONCLUSION: MSCs appear to improve sensorimotor and cognitive performance in PAIS-injured animals; however, the certainty of the evidence is low. Registration of the protocol of preclinical studies, appropriate sample size calculation, rigorous randomization, and reporting of the data on animal sex and survival are warranted. PROSPERO registration number: CRD42021239642.IMPACT: This is the first systematic review and meta-analysis of preclinical studies investigating the effects of MSCs in an experimental model of PAIS. MSCs appear to improve sensorimotor and cognitive performance in PAIS-injured neonatal animals. The cert...
Source: Pediatric Research - July 29, 2022 Category: Pediatrics Authors: Verena Lehnerer Anna Roidl Olga Romantsik Raphael Guzman Sven Wellmann Matteo Bruschettini Source Type: research

Stroke in pediatric ECMO: a target for prevention and improvement
Pediatr Res. 2022 Jul 29. doi: 10.1038/s41390-022-02199-1. Online ahead of print.NO ABSTRACTPMID:35906305 | DOI:10.1038/s41390-022-02199-1
Source: Pediatric Research - July 29, 2022 Category: Pediatrics Authors: Anne-Marie Guerguerian Source Type: research

Stroke in pediatric ECMO patients: analysis of the National Inpatient Sample (NIS) database
CONCLUSIONS: Over the years, there is an apparent increase in the diagnosis of stroke. All types of stroke in ECMO patients are associated with increased LOS, although mortality is increased in hemorrhagic and combined stroke only.IMPACT: Stroke is a commonly seen complication in pediatric patients supported by ECMO. Understanding the trends will help in identifying modifiable risk factors that predict poor outcomes in this patient population.PMID:35505077 | DOI:10.1038/s41390-022-02088-7
Source: Pediatric Research - May 3, 2022 Category: Pediatrics Authors: Chidiebere Ezetendu Orkun Baloglu Hasan F Othman Vanishree Nandakumar Samir Latifi Hany Aly Source Type: research