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Total 299 results found since Jan 2013.

What Are the Complications of Sickle Cell Trait?
Discussion Sickle cell disease (SCD) is a group of inherited blood disorders where there are abnormal hemoglobin molecules and the red blood cells take on a characteristic sickled shape instead of a rounded shape. Sickled hemoglobin provides an evolutionary advantage of giving the individual increased protection against severe and cerebral malaria. The sickled shape doesn’t move through the vascular system as well and therefore is more likely to aggregate in small vessels causing an increased risk of vaso-occlusive disease, acute chest syndrome, splenic sequestration, and priapism. There is also an increased risk of ...
Source: PediatricEducation.org - September 4, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Can Patent Foramen Ovales Cause Problems?
Discussion During fetal development, the heart primum and secundum septa grow and overlap leaving a small but important channel between the two atria. The foramen ovale is a flap valve moving blood from the right atrium into the left atrium directly and bypassing the high pressure pulmonary system. After birth and breathing air, the neonate’s lungs open up and the pulmonary vascular resistance decreases. The left atrium now has a relatively higher pressure than the right atria, and therefore pressure on the flap valve closes the foramen ovale. Usually within 6-12 months, the fusion of the primum and secundum of the f...
Source: PediatricEducation.org - July 24, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Left Ventricular Function and Dimensions Are Altered Early in Infants Developing Brain Injury in the Setting of Neonatal Encephalopathy
We evaluated the association between left cardiac three-dimensional echocardiographic parameters and brain injury in a single-center prospective study of neonates with neonatal encephalopathy. On day 2 of life, neonates with brain injury had higher left ventricle end-diastolic and stroke volume, but also higher peak global circumferential strain detected by 3D-echocardiogram.
Source: The Journal of Pediatrics - June 22, 2023 Category: Pediatrics Authors: Pierre Elias, Anie Lapointe, Pia Wintermark, Shiran Sara Moore, Daniela Villegas Martinez, Jessica Simoneau, Gabriel Altit Tags: Brief Reports Source Type: research

Utility of Inferior Vena Cava Distensibility and Respiratory Variation in Peak Aortic Blood Flow Velocity to Predict Fluid Responsiveness in Children with Shock
ConclusionsIn this study, authors found that ∆IVC and ΔVpeak were good predictors of fluid responsiveness in ventilated children with shock.
Source: Indian Journal of Pediatrics - June 6, 2023 Category: Pediatrics Source Type: research

Cerebral artery conditional blood velocity in sickle cell disease: a multicentre study and evidence for active treatment
Conclusion Since conditional blood velocity in cerebral arteries can progress to high values and predispose to stroke, the proportion of children with SCD who are affected (15.5%) raises the question of whether regular monitoring and proactive intervention ought to be the standard of care.
Source: Archives of Disease in Childhood - May 18, 2023 Category: Pediatrics Authors: Modebe, E., Nonyelu, C., Duru, A., Ezenwosu, O., Chukwu, B., Madu, A., Ezekekwu, C., Aneke, J., Izuka, M., Nri-Ezedi, C., Nnachi, O., Eze, A., Ajuba, I., Okwummuo, E., Chilaka, J., Onodugo, C., Fidelis-Ewa, U., Agwu, O., Anigbogu, I., Muoghalu, E., Okoye, Tags: ADC Global child health Source Type: research

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Evaluation of risk factors, functionalities, and quality of life in patients with pediatric acute arterial ischemic stroke
CONCLUSIONS: Determining the etiology and evaluating prognosis are important to plan effective treatment and rehabilitation for pediatric acute arterial ischemic stroke.PMID:37114696 | DOI:10.24953/turkjped.2022.350
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Fatih Mehmet Akif- Özdemir Ülkühan Öztoprak Ali Fettah Utku Arman Örün Mustafa K ılıç Fatma G ül Sarıkaya Bet ül Derinkuyu Deniz Y üksel Source Type: research