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Specialty: Pathology
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Total 1464 results found since Jan 2013.
Upregulated lncRNA NORAD can diagnose acute cerebral ischemic stroke patients and predict poor prognosis
CONCLUSIONS: NORAD was upregulated in AIS, which can discriminate AIS patients, and was closely correlated with severe development and poor prognosis of patients.PMID:37114966 | DOI:10.5114/fn.2022.121478
Source: Folia Neuropathologica - April 28, 2023 Category: Pathology Authors: Dongliang Liu Li Li Juanjuan Xu Wenping Luo Lu Pan Qilin Niu Daoxiang Wei Source Type: research
Loss of lncRNA UCA1 ameliorates the injury managed by cerebral ischemia-reperfusion by sponging miR-18a-5p
CONCLUSIONS: Elimination of UCA1 was favourable to the recovery of the rat model and cells from CI/R damage by efficaciously sponging miR-18a-5p.PMID:37114963 | DOI:10.5114/fn.2022.122497
Source: Folia Neuropathologica - April 28, 2023 Category: Pathology Authors: Jingyi Yan Yang Gao Jianyuan Huang Wei Gao Yang Li Baishun Lin Source Type: research
Upregulated lncRNA NORAD can diagnose acute cerebral ischemic stroke patients and predict poor prognosis
CONCLUSIONS: NORAD was upregulated in AIS, which can discriminate AIS patients, and was closely correlated with severe development and poor prognosis of patients.PMID:37114966 | DOI:10.5114/fn.2022.121478
Source: Folia Neuropathologica - April 28, 2023 Category: Pathology Authors: Dongliang Liu Li Li Juanjuan Xu Wenping Luo Lu Pan Qilin Niu Daoxiang Wei Source Type: research
Loss of lncRNA UCA1 ameliorates the injury managed by cerebral ischemia-reperfusion by sponging miR-18a-5p
CONCLUSIONS: Elimination of UCA1 was favourable to the recovery of the rat model and cells from CI/R damage by efficaciously sponging miR-18a-5p.PMID:37114963 | DOI:10.5114/fn.2022.122497
Source: Folia Neuropathologica - April 28, 2023 Category: Pathology Authors: Jingyi Yan Yang Gao Jianyuan Huang Wei Gao Yang Li Baishun Lin Source Type: research
A review on the role of SNHG8 in human disorders
Pathol Res Pract. 2023 Apr 7;245:154458. doi: 10.1016/j.prp.2023.154458. Online ahead of print.ABSTRACTSmall nucleolar RNA host gene 8 (SNHG8) is a long non-coding RNA that has physiological roles in epithelial and muscle satellite cells. This lncRNA has been reported to be over-expressed in a variety of cancer cell lines. Its silencing has attenuated tumor growth in animal models of cancers. SNHG8 can be served as a molecular sponge for some miRNAs to regulate their target genes. miR-634/ZBTB20, miR-335-5p/PYGO2, miR588/ATG7, miR-152/c-MET, miR-1270/BACH1, miR-491/PDGFRA, miR-512-5p/TRIM28, miR-149-5p/PPM1F, miR-542-3p/CC...
Source: Pathology, Research and Practice - April 12, 2023 Category: Pathology Authors: Soudeh Ghafouri-Fard Atefeh Harsij Bashdar Mahmud Hussen Mohammad Taheri Seyed Abdulmajid Ayatollahi Source Type: research
Differences in the post-stroke innate immune response between young and old
AbstractAging is associated to progressive changes impairing fundamental cellular and tissue functions, and the relationships amongst them through the vascular and immune systems. Aging factors are key to understanding the pathophysiology of stroke since they increase its risk and worsen its functional outcome. Most currently recognised hallmarks of aging are also involved in the cerebral responses to stroke. Notably, age-associated chronic low-grade inflammation is related to innate immune responses highlighted by induction of type-I interferon. The interferon program is prominent in microglia where it interrelates cell d...
Source: Seminars in Immunopathology - April 12, 2023 Category: Pathology Source Type: research
Atypical clinical presentation mimicking stroke in an adult patient caused by a rare diffuse leptomeningeal glioneuronal tumour
We report an atypical clinical presentation of DLGNT. A 48-year-old male was admitted to hospital with symptoms of ischaemic stroke. Magnetic resonance imaging of the head revealed contrast enhancement of the meninges and other parts of the brain. A stereotactic frame biopsy was performed on the patient, which revealed the DLGNT. Diffuse leptomeningeal glioneuronal tumours are mostly seen in individuals less than 18 years old and are characterized by slow growth and low-grade histological appearance. Diffuse leptomeningeal glioneuronal tumours can be aggressive in adults.PMID:36946275 | DOI:10.5114/pjp.2022.125822
Source: Polish Journal of Pathology - March 22, 2023 Category: Pathology Authors: Angelika Stapi ńska-Syniec Anna Gogol Albert Acewicz Micha ł Sobstyl Teresa Wierzba-Bobrowicz Wies ława Grajkowska Source Type: research
