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Specialty: Allergy & Immunology

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Total 749 results found since Jan 2013.

Bridging Therapy for Acute Stroke as the Initial Manifestation of Takayasu Arteritis: A Case Report and Review of Literature
We report a rare case of a patient with TA initially presenting with AIS treated with bridging therapy with full recovery of neurological function. Bridging therapy should be taken into consideration for AIS in patients with TA. Further study is needed in this regard.
Source: Frontiers in Immunology - April 30, 2021 Category: Allergy & Immunology Source Type: research

Dynamic Decrease in Eosinophil After Intravenous Thrombolysis Predicts Poor Prognosis of Acute Ischemic Stroke: A Longitudinal Study
ConclusionsDynamic decrease in eosinophil after intravenous thrombolysis predicts a 3-month poor outcome and death in AIS patients with r-tPA treatment and improved the predictive ability of conventional model. However, this result needs to be interpreted carefully in non-cardioembolic AIS patients.
Source: Frontiers in Immunology - July 7, 2021 Category: Allergy & Immunology Source Type: research

Analgecine regulates microglia polarization in ischemic stroke by inhibiting NF- κB through the TLR4 MyD88 pathway
Int Immunopharmacol. 2021 Jul 3;99:107930. doi: 10.1016/j.intimp.2021.107930. Online ahead of print.ABSTRACTTherapeutic strategies used to attenuate inflammation and to increase recovery of neurons after a stroke include microglia anti-inflammatory (M2) polarization and repression of proinflammatory (M1). Extracts isolated from Vaccina variola-inoculated rabbit skin, for example analgecine (AGC), have been used as a therapy for patients experiencing lower back pain associated with degenerative diseases of the spine for about twenty years. In the study presented here, neuroprotective effect associated with AGC was analyzed ...
Source: International Immunopharmacology - July 6, 2021 Category: Allergy & Immunology Authors: Cuicui Yang Shili Gong Xiaoping Chen Mingyang Wang Li Zhang Lan Zhang Chaoying Hu Source Type: research

Fraxetin protects rat brains from the cerebral stroke via promoting angiogenesis and activating PI3K/Akt pathway
CONCLUSION: Fraxetin has protective effects on the brain ischemia-reperfusion injury and promotes angiogenesis for cerebral repair via phosphorylation of PI3K and Akt.PMID:35285387 | DOI:10.1080/08923973.2022.2052893
Source: Immunopharmacology and Immunotoxicology - March 14, 2022 Category: Allergy & Immunology Authors: Yuhuan Cui Meihong Liu Li Zuo Haiyan Wang Jian Liu Source Type: research

The Role of the Gut Microbiota in the Development of Ischemic Stroke
An increasing number of studies have focused on the gut microbiota and its relationship with various neurological diseases. The gut microbiota can affect the metabolic status of the body, in addition to having an important impact on blood pressure, blood glucose, and atherosclerosis, all of which are risk factors for ischemic stroke. In this review, we summarized studies that included the physiological function of the gut microbiota and gut microbiota disorders related to the central nervous system, thus providing novel ideas for the prevention and treatment of ischemic stroke.
Source: Frontiers in Immunology - March 28, 2022 Category: Allergy & Immunology Source Type: research

Gut Dysbiosis Is Associated With the Severity of Cryptogenic Stroke and Enhanced Systemic Inflammatory Response
In conclusion, gut dysbiosis in CS patients was associated with the severity of CS and the systemic inflammation. Maintaining the intestinal homeostasis may be a potential strategy for the treatment of CS.
Source: Frontiers in Immunology - May 6, 2022 Category: Allergy & Immunology Source Type: research

Flu Vaccination Associated With Reduced Stroke Risk Flu Vaccination Associated With Reduced Stroke Risk
Researchers were surprised by the magnitude of the effect and the fact that it was observed in different adult age groups, for both sexes, and for those with and without stroke risk factors.Medscape Medical News
Source: Medscape Allergy Headlines - November 12, 2022 Category: Allergy & Immunology Tags: Cardiology News Source Type: news

Diagnostic model constructed by nine inflammation-related genes for diagnosing ischemic stroke and reflecting the condition of immune-related cells
ConclusionsTaken together, the diagnostic model constructed using the inflammation-related genes TNFSF10, ID1, PAQR8, OSR2, PDK4, PEX11B, TNIP1, FFAR2, and JUN exhibited high and specific diagnostic value for IS and reflected the condition of lymphocytes, monocytes, and neutrophils in the blood. The diagnostic model may contribute to the diagnosis of IS.
Source: Frontiers in Immunology - December 13, 2022 Category: Allergy & Immunology Source Type: research

Antiphospholipid antibodies in patients with stroke during COVID-19: A role in the signaling pathway leading to platelet activation
ConclusionsThis study demonstrates the presence of aPLs in a subgroup of COVID-19 patients who presented AIS, suggesting a role in the mechanisms contributing to hypercoagulable state in these patients. Detecting these antibodies as a serological marker to check and monitor COVID-19 may contribute to improve the risk stratification of thromboembolic manifestations in these patients.
Source: Frontiers in Immunology - March 2, 2023 Category: Allergy & Immunology Source Type: research

Integrated bioinformatics and machine-learning screening for immune-related genes in diagnosing non-alcoholic fatty liver disease with ischemic stroke and RRS1 pan-cancer analysis
ConclusionSix common candidate immune-related genes (PTGS2, FCGR1A, MMP9, VNN3, S100A12, and RRS1) of NAFLD and IS were identified, and a nomogram for diagnosing NAFLD with IS was established. RRS1 may serve as a candidate gene for predicting the prognosis of patients with cancer who have NAFLD complicated by IS, which could aid in their diagnosis and treatment.
Source: Frontiers in Immunology - April 5, 2023 Category: Allergy & Immunology Source Type: research

Orolingual angioedema associated with olmesartan use after recombinant tissue plasminogen activator treatment of acute stroke.
PMID: 24468260 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - February 1, 2014 Category: Allergy & Immunology Authors: Wang S, Bi X, Shan L, Zhou Y Tags: Ann Allergy Asthma Immunol Source Type: research