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Increased neuropil antibody prevalence in COVID-19 patients with acute ischemic stroke
CONCLUSION: Our results confirm the presence of neuropil antibodies in patients with COVID-19 infection and identify a putative antibody-driven association between AIS and COVID-19. The antigenic targets and potential pathogenic action of these antibodies need to be further explored.PMID:37634189 | DOI:10.1080/01616412.2023.2252282
Source: Neurological Research - August 27, 2023 Category: Neurology Authors: Birg ül Baştan Ece Erda ğ Turgeon Elif Şanlı Muhammet Duran Bayar Aysel B üşra Şişman Miray Atacan Ya şgüçlükal Cem I Smail K üçükali Erdem T üzün Sefer G ünaydın Source Type: research

Carotid free-floating thrombus in COVID-19: a cerebrovascular disorder of cytokine storm-related immunothrombosis
ConclusionsCOVID-19-induced immunothrombosis possibly played a significant pathogenic role in CFFT.
Source: Neurological Sciences - May 13, 2023 Category: Neurology Source Type: research

Blood-brain barrier function in response to SARS-CoV-2 and its spike protein
Neurol Neurochir Pol. 2023 Feb 22. doi: 10.5603/PJNNS.a2023.0014. Online ahead of print.ABSTRACTThe typical manifestation of coronavirus 2 (CoV-2) infection is a severe acute respiratory syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can also affect t he b rain, c ausing c hronic n eurological s ymptoms, variously known as long, post, post-acute, or persistent COVID-19 condition, and affecting up to 40% of patients. The symptoms (fatigue, dizziness, headache, sleep disorders, malaise, disturbances of memory and mood) usually are mild and resolve spontaneously. However, some patients develop acute ...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Łukasz Suprewicz Krzysztof Fiedoruk Agata Czarnowska Marcin Sadowski Agnieszka Strzelecka Peter A Galie Paul A Janmey Alina Ku łakowska Robert Bucki Source Type: research

Ischaemic stroke due to basilar artery occlusion in a puerperal patient with SARS-CoV-2 infection
CONCLUSION: Severe SARS-CoV-2 disease results in a prothrombotic state that correlates with the prognosis of the disease. The last trimester of pregnancy and the puerperium are known prothrombotic risk factors. Recommendations for anticoagulation management in pregnant patients with COVID-19 are based on limited evidence. This is the first case to be published in Spain involving cerebral arterial thrombosis in a pregnant patient with SARS-CoV-2 infection.PMID:35866535 | DOI:10.33588/rn.7504.2021373
Source: Revista de Neurologia - July 22, 2022 Category: Neurology Authors: M G ómez-Martí V Bosch ín F Puchades A Cerd án A Cunquero F Sanz J J Tamarit Source Type: research

Concurrent Cerebral, Splenic, and Renal Infarction in a Patient With COVID-19 Infection
Conclusion: In this case, a patient with multiple thrombotic events in the acute phase of COVID-19 infection, the delimitation of the inflammatory state through analytical markers as D-dimer helped to individualize the antithrombotic treatment (full anticoagulation or anticoagulation at intermediate doses plus antiplatelet treatment as used in our patient) and its duration. However, more data are needed to better understand the mechanisms and treatment of stroke in patients with COVID-19 infection.
Source: The Neurologist - May 1, 2022 Category: Neurology Tags: Case Report/Case Series Source Type: research

Ictogenesis of viral pneumonia: A comparison between SARS-CoV-2 and H1N1/H3N2
Epilepsy Behav. 2021 Dec 10;126:108470. doi: 10.1016/j.yebeh.2021.108470. Online ahead of print.ABSTRACTSeveral studies reported acute symptomatic seizures as a possible neurological complication of COVID-19 pneumonia. Apart from metabolic imbalances, hypoxia, and fever, other ictogenic mechanisms are likely related to an immune-mediated damage. The same mechanisms are shared by other respiratory viruses. Since neurotropic properties of SARS-CoV-2 have been questioned, we investigated whether SARS-CoV-2 has a similar ictogenic potential to other respiratory non-neurotropic viruses. We conducted a retrospective study identi...
Source: Epilepsy and Behaviour - December 13, 2021 Category: Neurology Authors: Chiara Milano Francesco Turco Chiara Pizzanelli Alessia Pascazio Enrico Tagliaferri Lorenzo Nesti Mauro Pistello Anna Lisa Capria Francesco Menichetti Francesco Forfori Enrica Bonanni Gabriele Siciliano Source Type: research

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