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Specialty: Neurology
Infectious Disease: Lyme Disease
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Total 58 results found since Jan 2013.
Pediatric stroke related to Lyme neuroborreliosis: Data from the Swiss NeuroPaediatric Stroke Registry and literature review.
CONCLUSIONS: Lyme Neuroborreliosis accounts for a small proportion of paediatric stroke even in an endemic country. The strong predilection towards posterior cerebral circulation with clinical occurrence of brainstem signs associated with meningeal symptoms and CSF lymphocytosis are suggestive features that should rapidly point to the diagnosis. This can confirmed by appropriate serological testing in the serum and CSF. Clinicians must be aware of this rare neurological complication of Lyme disease that demands specific antibiotic treatment.
PMID: 29208342 [PubMed - as supplied by publisher]
Source: European Journal of Paediatric Neurology - November 24, 2017 Category: Neurology Authors: Monteventi O, Steinlin M, Regényi M, Roulet-Perez E, Weber P, Fluss J Tags: Eur J Paediatr Neurol Source Type: research
Neurological Complications of Lyme Disease
information page compiled by the National Institue of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research
Stroke-like Phenomena Revealing Multifocal Cerebral Vasculitis in Pediatric Lyme Neuroborreliosis
We report a previously healthy 12-year-old boy who presented with acute left hemiparesis and meningeal signs. Neuroimaging failed to reveal any cerebral infarction but demonstrated a multifocal cerebral vasculitis involving small, medium and large-sized vessels affecting both the anterior and posterior circulation. Concentric contrast enhancement of the basilar artery was also observed. Further investigations and laboratory findings were consistent with Lyme neuroborreliosis. A rapidly favorable clinical outcome was obtained with appropriate antibiotic treatment along with antiaggregants and steroids. Lyme neuroborreliosis...
Source: Journal of Child Neurology - July 16, 2015 Category: Neurology Authors: Kurian, M., Pereira, V. M., Vargas, M. I., Fluss, J. Tags: Brief Communication Source Type: research
Cerebral vasculitis and stroke due to Lyme neuroborreliosis: A favorable clinical outcome after early antibiotic treatment
Lyme neuroborreliosis (LNB) is a disease of the nervous system caused by the spirochete Borrelia burgdorferi sensu lato genospecies, which is transmitted by the bite of infected ticks. Approximately 15% of patients with Lyme borreliosis develop neurological manifestations; most frequently meningitis, cranial neuritis or polyradiculitis [1]. Ischemic stroke due to cerebral vasculitis is rarely (
Source: Journal of the Neurological Sciences - January 24, 2017 Category: Neurology Authors: Meinie Seelen, Ido R. van den Wijngaard, Rob S. Rundervoort Tags: Letter to the Editor Source Type: research
Streptococcus pneumoniae meningitis and intracranial vasculopathy: Clinical correlation with improving transcranial Doppler hemodynamics (P1.322)
Conclusions:Antibiotic treatment for S. pneumoniae meningitis correlated with improvement in clinical status and TCD hemodynamics. Serial TCDs may be a potentially useful strategy in the management of bacterial meningitis.Disclosure: Dr. Idris has nothing to disclose. Dr. Tai has nothing to disclose. Dr. Tan has nothing to disclose. Dr. Tan has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Idris, M. I., Tai, S. M. L., Tan, C. T., Tan, K. S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research
Lyme neuroborreliosis-associated cerebrovascular events in the Finnish endemic area
Neuroborreliosis is a rare cause of cerebral vasculitis and stroke. The incidence of Lyme borreliosis in Finland has been increasing in the last 20 years, so we expect that Lyme neuroborreliosis–associated vasculitis can be a more common cause of stroke in the future.
Source: Journal of the Neurological Sciences - June 16, 2021 Category: Neurology Authors: Maria Mironova, Elisa Kortela, Satu Kurkela, Mari Kanerva, Sami Curtze Source Type: research
A study on the association between infectious burden and Alzheimer's disease
ConclusionsIB consisting of CMV, HSV‐1, B. burgdorferi, C. pneumoniae and H. pylori is associated with AD. This study supports the role of infection/inflammation in the etiopathogenesis of AD.
Source: European Journal of Neurology - June 9, 2014 Category: Neurology Authors: X.‐L. Bu, X.‐Q. Yao, S.‐S. Jiao, F. Zeng, Y.‐H. Liu, Y. Xiang, C.‐R. Liang, Q.‐H. Wang, X. Wang, H.‐Y. Cao, X. Yi, B. Deng, C.‐H. Liu, J. Xu, L.‐L. Zhang, C.‐Y. Gao, Z.‐Q. Xu, M. Zhang, L. Wang, X.‐L. Tan, X. Xu, H.‐D. Zhou, Y. Tags: Original Article Source Type: research
Clinical Reasoning: A 28-year-old man with progressive gait disturbance and encephalopathy
A 28-year-old man with sickle cell disease presented with 7 months of difficulty walking. Initial examination 3 months prior to admission to our hospital was thought to be consistent with a polyneuropathy. He was areflexic, was unable to stand on toes or heels with decreased sensation on the left foot to light touch and vibration, had difficulty with heel to shin, and was unable to perform tandem gait. Laboratory tests revealed anemia (hemoglobin 7.2 g/dL) and elevated creatinine (1.49 g/dL). HIV, antinuclear antibodies, antineutrophil cytoplasmic antibodies, hepatitis serologies, rapid plasma reagin, thyroid-stimulating h...
Source: Neurology - December 8, 2014 Category: Neurology Authors: Massaro, A. M., Pruitt, A. Tags: Stroke in young adults, MRI, Gait disorders/ataxia, All Oncology RESIDENT AND FELLOW SECTION Source Type: research
Posterior spinal cord infarctions due to neurosyphilis
An 86-year-old patient with multiple vascular risk factors including 3 previous strokes woke up with a sensation of wet lower limbs, with bilateral loss of proprioception in legs on examination. Cervical MRI showed 2 acute medullary ischemic lesions in the posterior columns at level C3 and C4 (figure 1, A–D). Biological screening including HIV serology, Treponema pallidum hemagglutination assay (TPHA), Venereal Disease Research Laboratory test (VDRL), and Lyme disease serology showed an increased TPHA titer of 1:320, with a negative VDRL.
Source: Nature Clinical Practice - December 8, 2014 Category: Neurology Authors: Bill, O., Du Pasquier, R. A., Michel, P. Tags: CT, Parasitic infections, Clinical neurology examination, All Cerebrovascular disease/Stroke, Spinal cord infarction Cases Source Type: research
Amyotrophic Lateral Sclerosis (ALS) with Laboratory Abnormalities of Unknown Significance (LAUS) --Where Does It Begin and Where Does It End? (P4.144)
CONCLUSIONS: Further detailed analysis of progression rate by site of onset, sex, age, treatment will require assimilation of clinic-based datasets of properly analyzed ALS-LAUS patients from multiple clinic sites. The appropriate role of IVIg in ALS-LAUS patients requires further study following explication of the natural history of these patients compared with non-ALS-LAUS patients. The determination as to whether auto-antibodies to additional antigens may play a role in the progression rate of ALS-LAUS compared with sporadic ALS needs to be systematically studied. Study Supported by: Carolinas ALS Research FundDisclosur...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Brooks, B., Bravver, E., Langford, V., Alwan, M., Smith, N., Lucas, N., Nichols, M., Belcher, S., Lary, C., Nemeth, J., Russo, P., Wright, K., Ward, A., Holsten, S., Fischer, M., Bockenek, W., Desai, U., Lindblom, S. C., Pacicco, T., Sanjak, M. Tags: Neuroepidemiology: ALS Source Type: research
Cerebrovascular Events in Lyme Neuroborreliosis
Cerebrovascular events in neuroborreliosis are a rare condition described only in isolated or small case series. No specific clinical or radiological features have been identified, and diagnosis is based on very different criteria.
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2015 Category: Neurology Authors: Basile Wittwer, Sébastien Pelletier, Xavier Ducrocq, Louis Maillard, Gioia Mione, Sébastien Richard Source Type: research
Isolated Tongue Hemi-Atrophy from Hypoglossal-Vertebral Entrapment Syndrome (P3.377)
Conclusion: Hypoglossal vertebral entrapment syndrome from a structural vascular anomaly or anomalous vascular course is an extremely rare cause of isolated hypoglossal nerve palsy. Only a few cases have been reported in the literature. Imaging studies and careful exclusion of other potential etiologies is essential to establish the diagnosis.Disclosure: Dr. Roy has nothing to disclose. Dr. Bakradze has nothing to disclose. Dr. Ollenschleger has nothing to disclose. Dr. Felice has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Roy, B., Bakradze, E., Ollenschleger, M., Felice, K. Tags: General Neurology Source Type: research
The Evaluation and Management of Alternative Diagnoses in Amyotrophic Lateral Sclerosis (P5.091)
Conclusions: Treatment with intravenous steroids, immunoglobulin and surgical interventions prior to diagnosis of ALS is associated with a significantly prolonged mean ODI.Disclosure: Dr. Kannan has nothing to disclose. Dr. Glass has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kannan, M., Glass, J. Tags: Neuroepidemiology: Neuro-oncology and ALS Source Type: research
A Rare Case of Central Nervous System Tuberculosis Presenting as Transient Splenial Lesion: Case Report and Literature Review (P1.320)
Conclusions:Based on literature review, the transient splenial lesion of corpus callosum has never been reported in patients with CNS tuberculosis. The mechanisms underlying transient splenial lesions may due to intramyelinic edema and inflammatory cell infiltration. This hypothesis supported by the MR spectroscopy findings in our patient. Since early diagnosis and treatment can reduce mortality and morbidity, patients with isolated splenial lesion warrant diagnostic tests for CNS tuberculosis.Study Supported by:The authors report no disclosures relevant to the manuscript.Disclosure: Dr. Wu has nothing to disclose. Dr. Che...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wu, J.-W., Chen, S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research
Burden of Cerebrovascular Disease and its association in the clinical characteristics, Incidence and outcomes in the hospitalized patients with Community-Acquired Pneumonia in Louisville, KY (P1.321)
Conclusions:This study documents worse clinical outcomes and significantly increased mortality in the hospitalized patients with community acquired pneumonia and associated cerebrovascular disease.Disclosure: Dr. SirDeshpande has nothing to disclose. Dr. Kolikonda has nothing to disclose. Dr. Peyrani has nothing to disclose. Dr. Ramirez has nothing to disclose. Dr. Arnold has nothing to disclose. Dr. Wiemken has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: SirDeshpande, P., Kolikonda, M., Peyrani, P., Ramirez, J., Arnold, F., Wiemken, T. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research
